LEADER 00947nam0-22003011--450- 001 990006015120403321 005 20070118102412.0 035 $a000601512 035 $aFED01000601512 035 $a(Aleph)000601512FED01 035 $a000601512 100 $a20000112d1974----km-y0itay50------ba 101 0 $aita 102 $aIT 105 $ay-------001yy 200 1 $aRelazione programmatica$eai sensi dell'art. 10 della legge 22 dicembre 1956 n. 1589$fpresentata al Parlamento dal Ministro delle Partecipazioni Statali, Antonio Gullotti 210 $aRoma$cEd. Barbi$d1974 215 $a402 p.$d24 cm 676 $a351.082$v20$zita 702 1$aGullotti,$bAntonio 710 01$aItalia.$bMinistero delle partecipazioni statali$0354185 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990006015120403321 952 $aXVII 986$b99973$fFGBC 959 $aFGBC 996 $aRelazione programmatica$9579299 997 $aUNINA LEADER 03388nam 2200601 450 001 9910480192103321 005 20211029185421.0 010 $a0-8218-7597-3 010 $a0-8218-5012-1 035 $a(CKB)3240000000069536 035 $a(EBL)3112951 035 $a(SSID)ssj0000712578 035 $a(PQKBManifestationID)11407524 035 $a(PQKBTitleCode)TC0000712578 035 $a(PQKBWorkID)10644912 035 $a(PQKB)10578193 035 $a(MiAaPQ)EBC3112951 035 $a(WaSeSS)Ind00039539 035 $a(PPN)197103294 035 $a(EXLCZ)993240000000069536 100 $a19820707h19821982 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPlane ellipticity and related problems /$f[edited by Robert P. Gilbert] 210 1$aProvidence, Rhode Island :$cAmerican Mathematical Society,$d[1982] 210 4$dİ1982 215 $a1 online resource (255 p.) 225 1 $aContemporary mathematics,$x0271-4132 ;$vvolume 11 300 $a"Proceedings of the Special Session on Elliptic Systems in the Plane, 87th Annual Meeting of the American Mathematical Society, held in San Francisco, California, January 7-11, 1981"--Verso title page. 311 08$aPrint version: Special Session on Elliptic Systems in the Plane. Plane ellipticity and related problems. Providence, Rhode Island : American Mathematical Society, [1982] vii, 245 pages ; 26 cm. Contemporary mathematics ; v. 11 9780821850121 320 $aIncludes bibliographies. 327 $a""Contents""; ""Introduction""; ""The Finite Element Method and Non-Local Boundary Conditions for Scattering Problems""; ""Boundary Value Problems Associated with First Order Elliptic Systems in the Plane""; ""Coupled Variational Inequalities for Flow From a Non-Symmetric Ditch""; ""Bers-Vekua Equations of Two Complex Variables""; ""Fourier Analysis on the Unit Sphere: A Hypercomplex Approach""; ""Function Theory for Generalized Beltrami Systems""; ""On a Variational Inequality for the Hodograph Method""; ""Nonlinear Boundary Value Problems of Riemann-Hilbert Type"" 327 $a""Spinor Valued Regular Functions""""Approximate Solutions of an Elliptic Equation on Select Domains""; ""Gradient Bounds for a Class of Second Order Elliptic Equations""; ""Elliptic Systems in the Plane Associated with Certain Partial Differential Equations of Deformable Media""; ""A Homogeneous Linear PDE in the Plane, With Smooth Real Coefficients, Whose Only Solution is the Zero Function""; ""The Newtonian Potential For a Generalized Cauchy-Riemann Operator in Euclidean Space"" 410 0$aContemporary mathematics (American Mathematical Society) ;$v11. 606 $aDifferential equations, Elliptic$vCongresses 606 $aFunctions of complex variables$vCongresses 608 $aElectronic books. 615 0$aDifferential equations, Elliptic 615 0$aFunctions of complex variables 676 $a515.3/53 702 $aGilbert$b Robert P.$f1932- 712 02$aAmerican Mathematical Society.$bMeeting$d(87th :$f1981 :$eSan Francisco, Calif), 712 12$aSpecial Session on Elliptic Systems in the Plane 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910480192103321 996 $aPlane Ellipticity and Related Problems$9381458 997 $aUNINA LEADER 04185nam 22006855 450 001 9910506401703321 005 20251113211601.0 010 $a981-16-4521-3 024 7 $a10.1007/978-981-16-4521-1 035 $a(CKB)4950000000280385 035 $a(MiAaPQ)EBC6788058 035 $a(Au-PeEL)EBL6788058 035 $a(OCoLC)1280276097 035 $a(DE-He213)978-981-16-4521-1 035 $a(PPN)258302542 035 $a(EXLCZ)994950000000280385 100 $a20211020d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHereditary Breast and Ovarian Cancer $eMolecular Mechanism and Clinical Practice /$fedited by Seigo Nakamura, Daisuke Aoki, Yoshio Miki 205 $a1st ed. 2021. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2021. 215 $a1 online resource (324 pages) $cillustrations 311 08$a981-16-4520-5 327 $a1 History, Advancements, and Future Strategies -- 2 Molecular basis of BRCA1 and BRCA2 - Homologous recombination deficiency and tissue-specific carcinogenesis -- 3 Genetic Testing -- 4 Variants of uncertain significances in hereditary breast and ovarian cancer -- 5 Genetic counseling in Hereditary Breast and Ovarian Cancer -- 6 Hereditary Breast Cancer -- 7 Hereditary Ovarian Cancer -- 8 Risk-Based Breast Cancer Screening -- 9 Chemoprevention for Breast Cancer -- 10 Chemoprevention for Ovarian Cancer -- 11 Risk-Reducing Mastectomy (RRM) -- 12 Risk-reducing salpingo-oophorectomy (RRSO) -- 13 Panel Testing -- 14 Germline Findings through Precision Oncology for Ovarian Cancer -- 15 Germline Findings from Genetic Testing for Breast Cancer -- 16 Hereditary Breast and Ovarian Cancer (HBOC) Database -- 17 Ethical Issues: Overview in Genomic analysis and Clinical Context -- 18 PARP Inhibitors-Mechanism of action -- 19 PARPi - Efficacy in Hereditary Breast Cancer -- 20 Efficacy of Poly ADP-Ribose Polymerase Inhibitors for Hereditary Ovarian Cancer. 330 $aThis highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease.Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars. 606 $aInternal medicine 606 $aSurgery 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aMedical genetics 606 $aInternal Medicine 606 $aSurgery 606 $aBiomedical Research 606 $aMedical Genetics 606 $aBiomedical Research 615 0$aInternal medicine. 615 0$aSurgery. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aMedical genetics. 615 14$aInternal Medicine. 615 24$aSurgery. 615 24$aBiomedical Research. 615 24$aMedical Genetics. 615 24$aBiomedical Research. 676 $a616.99449042 702 $aAoki$b Daisuke 702 $aMiki$b Yoshio 702 $aNakamura$b Seigo 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910506401703321 996 $aHereditary breast and ovarian cancer$92567415 997 $aUNINA