LEADER 01528nas 2200481-a 450 001 996398343903316 005 20230203213020.0 011 $a2042-8367 035 $a(DE-599)ZDB2479310-3 035 $a(OCoLC)276089708 035 $a(CKB)1000000000429488 035 $a(CONSER)--2008244011 035 $a(EXLCZ)991000000000429488 100 $a20080722b20082014 --- - 101 0 $aeng 181 $ctxt$2rdacontent 182 $cn$2rdamedia 200 00$aEthnicity and inequalities in health and social care 210 $aBrighton, East Sussex $cPavilion Pub 210 2 $aHove $cPier Professional 210 3 $aBingley, UK $cEmerald Group Pub 311 $a1757-0980 531 $aETHNICITY & INEQUALITIES IN HEALTH AND SOCIAL CARE 606 $aMinorities$xMedical care$vPeriodicals 606 $aEthnic groups$vPeriodicals 606 $aDelivery of Health Care 606 $aCultural Competency 606 $aEthnic Groups 606 $aEthnic groups$2fast$3(OCoLC)fst00915958 606 $aMinorities$xMedical care$2fast$3(OCoLC)fst01023194 608 $aPeriodical. 608 $aPeriodicals.$2fast 615 0$aMinorities$xMedical care 615 0$aEthnic groups 615 12$aDelivery of Health Care. 615 22$aCultural Competency. 615 22$aEthnic Groups. 615 7$aEthnic groups. 615 7$aMinorities$xMedical care. 906 $aJOURNAL 912 $a996398343903316 996 $aEthnicity and inequalities in health and social care$92032806 997 $aUNISA LEADER 04345nam 22006975 450 001 9910502666103321 005 20251113180011.0 010 $a3-030-85536-8 024 7 $a10.1007/978-3-030-85536-9 035 $a(CKB)4100000012026398 035 $a(MiAaPQ)EBC6726393 035 $a(Au-PeEL)EBL6726393 035 $a(OCoLC)1268325517 035 $a(PPN)258058609 035 $a(DE-He213)978-3-030-85536-9 035 $a(EXLCZ)994100000012026398 100 $a20210913d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCardiomyocytes in Health and Disease /$fby Chandrasekharan C. Kartha 205 $a1st ed. 2021. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2021. 215 $a1 online resource (356 pages) 225 1 $aBiomedical and Life Sciences Series 311 08$a3-030-85535-X 320 $aIncludes bibliographical references and index. 327 $aSection I: Normal Cardiomyocyte and its Growth -- 1. Structure and Function of Cardiomyocyte -- 2. Development of Cardiomyocyte -- 3. Cell Cycle Regulation in Cardiomyocytes -- 4. Cardiac Fibroblast and Cardiomyocyte Growth -- 5. Role of Endocardium and Epicardium in Generation of Cardiomyocytes -- Cardiomyocytes in the Mammalian Adult Heart -- 7. Energy Metabolism in Cardiomyocytes -- Section II: Cardiomyocyte Responses 8. Response of Cardiomyocytes to Mechanical Stress -- Cardiomyocyte Responses to Hormones 10. Sequelae of Genetic Defects in Cardiomyocytes -- 11. Response and Effects of Cardiomyocyte Progenitors in the Infarcted Heart -- Section III: Cardiomyocyte Aging and Death -- 12. Cardiomyocyte Senescence -- 13. Mechanisms of Cardiomyocyte Death -- 14. Cardiomyocyte Response to Ischemic Injury -- 15. Cardiomyocytes in Heart Failure -- Section IV: Cardiomyocyte Regeneration -- 16. Endogenous Mechanisms for Cardiomyocyte Regeneration -- 17. Mechanisms to Induce Cardiomyocyte Proliferation -- 18. Cell Sources of Cardiomyocytes for Heart Repair -- 19. Reprograming Fibroblasts for Cardiomyocytes and Progenitors -- Section V: Translational Aspects of Cardiomyocyte Biology -- 20. Clinical Translation of Discoveries in Cardiomyocyte Biology. 330 $aThis book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon. . 410 0$aBiomedical and Life Sciences Series 606 $aCardiovascular system 606 $aPhysiology 606 $aCardiology 606 $aRegenerative medicine 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCardiovascular Physiology 606 $aCardiology 606 $aRegenerative Medicine and Tissue Engineering 606 $aBiomedical Research 615 0$aCardiovascular system. 615 0$aPhysiology. 615 0$aCardiology. 615 0$aRegenerative medicine. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 14$aCardiovascular Physiology. 615 24$aCardiology. 615 24$aRegenerative Medicine and Tissue Engineering. 615 24$aBiomedical Research. 676 $a612.17 700 $aKartha$b C. Chandrasekharan$01242084 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910502666103321 996 $aCardiomyocytes in health and disease$92881108 997 $aUNINA