LEADER 05056nam 2200565 450 001 9910139000003321 005 20170816142656.0 010 $a3-527-67374-1 010 $a3-527-33596-X 010 $a3-527-67373-3 035 $a(CKB)2550000001127042 035 $a(EBL)1443914 035 $a(OCoLC)861080200 035 $a(MiAaPQ)EBC1443914 035 $a(EXLCZ)992550000001127042 100 $a20131029h20142014 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aMALDI MS $ea practical guide to instrumentation, methods and applications /$fedited by Franz Hillenkamp and Jasna Peter-Katalinic 205 $a2nd ed. 210 1$aWeinheim :$cWiley Blackwell,$d[2014] 210 4$d©2014 215 $a1 online resource (477 p.) 300 $aDescription based upon print version of record. 311 $a3-527-33331-2 311 $a1-299-96455-9 320 $aIncludes bibliographical references and index. 327 $aCover; Related Titles; Title page; Copyright page; Contents; Preface to the Second Edition; List of Contributors; 1: The MALDI Process and Method; 1.1 Introduction; 1.2 Analyte Incorporation; 1.3 Absorption of the Laser Radiation; 1.4 The Ablation/Desorption Process; 1.5 Ionization; 1.6 Fragmentation of MALDI Ions; 1.7 MALDI of Noncovalent Complexes; 1.8 The Optimal Choice of Matrix: Sample Preparation; 1.8.1 Surface Preparation; 1.8.2 Anchor Sample Plates; 1.8.3 Matrix Additives and Influence of the Sample Plate Surface; Abbreviations; References; 2: MALDI Mass Spectrometry Instrumentation 327 $a2.1 Introduction2.2 Lasers for MALDI-MS; 2.3 Fragmentation of MALDI Ions; 2.3.1 MALDI at Elevated Pressure; 2.3.2 Tandem Mass Spectrometry of MALDI Ions; 2.4 Mass Analyzers; 2.4.1 Axial TOF Mass Spectrometers; 2.4.2 Reflectron TOF Mass Spectrometers; 2.4.3 Tandem TOF Mass Spectrometers; 2.4.4 Orthogonal TOF Mass Analyzers; 2.4.5 Tandem Mass Spectrometry in oTOF Mass Analyzers; 2.4.6 Ion Detectors and Data Processing in MALDI-TOF Analyzers; 2.5 Fourier Transform Ion Cyclotron Resonance Mass Spectrometers; 2.5.1 Tandem Mass Spectrometry on FTICR Mass Spectrometers 327 $a2.6 Quadrupole Ion Trap Mass Spectrometers2.6.1 RF-Only Ion Guides and LIT Mass Spectrometers; 2.6.2 Tandem Mass Spectrometry on QIT Mass Spectrometers; 2.7 Hybrid Mass Spectrometers; 2.7.1 Quadrupole TOF Mass Spectrometers; 2.7.2 Quadrupole FT Mass Spectrometers; 2.7.3 QIT-TOF Mass Spectrometers; 2.7.4 Ion Mobility oTOF Mass Spectrometers; 2.7.5 Orbitrap; 2.8 Future Directions; Definitions and Acronyms; References; 3: MALDI-MS in Protein Chemistry and Proteomics; 3.1 Introduction; 3.2 Sample Preparation for Protein and Peptide Analysis by MALDI-MS 327 $a3.3 Strategies for Using MALDI-MS in Protein Biochemistry3.3.1 Peptide Mass Mapping of Purified Proteins; 3.3.2 Peptide Sequencing by MALDI-MS/MS; 3.3.3 Analysis of Post-Translational Modifications; 3.4 Applications of MALDI-MS in Proteomics; 3.4.1 Protein Identification by MALDI-MS Peptide Mass Mapping; 3.4.2 Quantitation of Proteins by MALDI-MS; 3.5 Computational Tools for Protein Analysis by MALDI-MS; 3.6 Clinical Applications of MALDI-MS; 3.7 Conclusions; Acknowledgments; References; 4: MALDI-Mass Spectrometry Imaging; 4.1 Introduction 327 $a4.2 History of Mass Spectrometry Imaging (MSI) and Microprobing Techniques4.3 MALDI in Micro Dimensions: Instruments and Mechanistic Differences; 4.4 Visualization of Mass Spectrometric Information; 4.5 Data Processing and Data Exchange; 4.6 Matrix Deposition for High-Resolution Imaging; 4.7 Organisms, Organs, and Tissues: MALDI Imaging at Various Lateral Resolutions; 4.7.1 Phospholipid Analysis; 4.7.2 Peptide Analysis; 4.7.3 Drug Monitoring; 4.8 Whole-Cell and Single-Cell Analysis; 4.8.1 Cellular Analysis; 4.8.2 Individually Isolated Cells; 4.8.3 Direct Cellular and Subcellular Imaging 327 $a4.9 Cell Sorting and Capturing 330 $aThis authoritative book on MALDI MS, now finally available in its second edition and edited by one of its inventors, gives an in-depth description of the many different applications, along with a detailed discussion of the technology itself.Thoroughly updated and expanded, with contributions from key players in the field, this unique book provides a comprehensive overview of MALDI MS along with itspossibilities and limitations.The initial chapters deal with the technology and the instrumental setup, followed by chapters on the use of MALDI MS in protein research (including proteomi 606 $aMatrix-assisted laser desorption-ionization 608 $aElectronic books. 615 0$aMatrix-assisted laser desorption-ionization. 676 $a547.70154365 701 $aHillenkamp$b F$0855863 701 $aPeter-Katalinic?$b Jasna$0855864 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139000003321 996 $aMALDI MS$91910721 997 $aUNINA LEADER 01917 am 2200517 n 450 001 9910495699403321 005 20200129 010 $a2-7574-2676-1 024 7 $a10.4000/books.septentrion.86948 035 $a(CKB)4100000011665479 035 $a(FrMaCLE)OB-septentrion-86948 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/86978 035 $a(PPN)252448073 035 $a(EXLCZ)994100000011665479 100 $a20201217j|||||||| ||| 0 101 0 $afre 135 $auu||||||m|||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 13$aLa crise du plaisir $e(1740-1830) /$fPeter Cryle 210 $aVilleneuve d'Ascq $cPresses universitaires du Septentrion$d2020 215 $a1 online resource (232 p.) 225 1 $aObjet 311 $a2-85939-792-2 330 $aLa fin du dix-neuvième siècle nous a appris une vérité douteuse : que la sexualité humaine est universelle. Depuis cette époque, nous nous sommes habitués à la singularité du plaisir, dans son principe toujours le même. Mais au dix-huitième siècle, on préférait parler de plaisirs au pluriel, et de l?art de les varier. Comment, dans les textes libertins et pornographiques, ce pluriel s?est-il transformé en singulier ? Cette transformation, historiquement, suppose une véritable crise. 606 $aLiterature (General) 606 $aromantisme 606 $alittérature 606 $aplaisir 606 $acrise 610 $aromantisme 610 $alittérature 610 $aplaisir 610 $acrise 615 4$aLiterature (General) 615 4$aromantisme 615 4$alittérature 615 4$aplaisir 615 4$acrise 700 $aCryle$b Peter$01307492 801 0$bFR-FrMaCLE 906 $aBOOK 912 $a9910495699403321 996 $aLa crise du plaisir$93028801 997 $aUNINA LEADER 01721nam 2200433 450 001 9910375785103321 005 20230809231557.0 035 $a(CKB)4100000004910100 035 $a(WaSeSS)IndRDA00104260 035 $a(EXLCZ)994100000004910100 100 $a20180905d2017 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aL@S '17 $eproceedings of the fourth (2017) ACM Conference on Learning @ Scale : April 20-21, 2017, Cambridge, MA, USA /$fsponsored by ACM 210 1$aNew York :$cACM,$d2017. 215 $a1 online resource (340 pages) 300 $aIncludes index. 311 $a1-4503-4450-X 517 1 $aLearning @ Scale '17 :$eproceedings of the fourth (2017) Association for Computing Machinery Conference on Learning @ Scale : April 20-21, 2017, Cambridge, Massachusetts, United States of America 517 1 $aLearning @ Scale 2017 517 1 $aProceedings of the fourth (2017) ACM Conference on Learning @ Scale 517 1 $aProceedings of the fourth (2017) Association for Computing Machinery Conference on Learning @ Scale 606 $aMOOCs (Web-based instruction)$vCongresses 606 $aDistance education$xComputer-assisted instruction$vCongresses 606 $aInternet in education$vCongresses 615 0$aMOOCs (Web-based instruction) 615 0$aDistance education$xComputer-assisted instruction 615 0$aInternet in education 676 $a371.3344678 712 02$aAssociation for Computing Machinery, 801 0$bWaSeSS 801 1$bWaSeSS 906 $aBOOK 912 $a9910375785103321 996 $aL@S '17$92158274 997 $aUNINA LEADER 03247nam 22007335 450 001 9910731459103321 005 20251009083529.0 010 $a9783031334269 010 $a3031334264 024 7 $a10.1007/978-3-031-33426-9 035 $a(MiAaPQ)EBC30602590 035 $a(Au-PeEL)EBL30602590 035 $a(DE-He213)978-3-031-33426-9 035 $a(PPN)272273481 035 $a(CKB)27106526200041 035 $a(OCoLC)1385326258 035 $a(EXLCZ)9927106526200041 100 $a20230618d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Physics of Planet Earth and Its Natural Wonders /$fby Dmitry Livanov 205 $a1st ed. 2023. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2023. 215 $a1 online resource (305 pages) 225 0 $aPhysics and Astronomy Series 311 08$aPrint version: Livanov, Dmitry The Physics of Planet Earth and Its Natural Wonders Cham : Springer,c2023 9783031334252 327 $a1 The Earth in the Solar System -- 2 The Earth and the Moon -- 3 The Depths and the Surface of the Earth -- 4 The Earth?s Atmosphere -- 5 The Ocean -- 6 Fresh Water on the Earth -- 7 The Weather and Climate. 330 $aFrom earthquakes to the northern lights and tsunamis to glacier movement, the author explains thousands of phenomena in the world around us. All of this is done using language that is simple and understandable, and at the same time this book does not try to deceive the reader, as materials of this nature often do, but uses exact physical formulas where they are needed. This book serves as an invaluable reference for physics teachers and should inspire high school students to study physics. Many of them will very likely be able to understand that riveting events and phenomena lie behind those very same formulas that just yesterday seemed so boring. This is an excellent and unique way of easily submerging oneself into the world of science and a non-stop intellectual challenge that lures the reader in much more than any game of chess. Sir Andre Geim, 2010 Nobel Prize Laureate in Physics. 606 $aGeophysics 606 $aPlanetary science 606 $aGravitation 606 $aClimatology 606 $aOceanography 606 $aAtmospheric science 606 $aGeophysics 606 $aPlanetary Science 606 $aNewtonian Physics 606 $aClimate Sciences 606 $aOcean Sciences 606 $aAtmospheric Science 615 0$aGeophysics. 615 0$aPlanetary science. 615 0$aGravitation. 615 0$aClimatology. 615 0$aOceanography. 615 0$aAtmospheric science. 615 14$aGeophysics. 615 24$aPlanetary Science. 615 24$aNewtonian Physics. 615 24$aClimate Sciences. 615 24$aOcean Sciences. 615 24$aAtmospheric Science. 676 $a550 700 $aLivanov$b Dmitry$01369399 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910731459103321 996 $aThe Physics of Planet Earth and Its Natural Wonders$93395549 997 $aUNINA