LEADER 04375nam 22006135 450 001 9910494563403321 005 20260206092144.0 010 $a981-16-3615-X 024 7 $a10.1007/978-981-16-3615-8 035 $a(CKB)5590000000549886 035 $a(MiAaPQ)EBC6711711 035 $a(Au-PeEL)EBL6711711 035 $a(OCoLC)1265347843 035 $a(PPN)257356975 035 $a(DE-He213)978-981-16-3615-8 035 $a(EXLCZ)995590000000549886 100 $a20210823d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHepatitis B Virus and Liver Disease /$fedited by Jia-Horng Kao 205 $a2nd ed. 2021. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2021. 215 $a1 online resource (507 pages) 225 1 $aMedicine Series 300 $aIncludes index. 311 08$a981-16-3614-1 327 $a1 Molecular Virology and Life Cycle of Hepatitis B Virus -- 2 Unmet Needs in Basic Research of Hepatitis B Virus Infection: In Vitro and In Vivo Models -- 3 Unmet Needs Clinical Research Hepatitis B -- 4 Immunopathogenesis of Hepatitis B Virus Infection -- 5 Pathology of Hepatitis B Virus (HBV) Infection and HBV-related Hepatocellular Carcinoma -- 6 Molecular Carcinogenesis of Hepatitis B Virus-Related Hepatocellular Carcinoma -- 7 Epidemiology and Natural History of Hepatitis B Virus Infection -- 8 Hepatitis B Vaccines -- 9 Viral and Host Factors Affecting Disease Progression of Hepatitis B Virus Infection -- 10 Novel Biomarkers for the Management of Chronic Hepatitis B Virus Infection -- 11 Chronic hepatitis B virus infection: Non-invasive assessment of liver disease -- 12 Chronic Hepatitis B Virus Infection: Interferon Therapy and Long-Term Outcomes -- 13 Nucleos(t)ide therapy and long-term outcomes -- 14 Combination therapy -- 15 Treatment of HCV, HDV or HIV Coinfections -- 16 Management ofChronic Hepatitis B Virus Infection in Children and Pregnant Women -- 17 Occult Hepatitis B Infection -- 18 Hepatitis B Virus Reactivation and Management of Patients undergoing Immunosuppression -- 19 Novel Therapy for Functional Cure of Chronic Hepatitis B Virus Infection -- 20 Is Cure of Hepatitis B infection a mission possible?. 330 $aThis book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, novel biomarkers, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments for possible functional cure of HBV infection. In this second edition, authors provides recent updates in epidemiology, biomarkers, antivirus therapy, and novel therapy for functional cure of chronic hepatitis B virus infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection. 410 0$aMedicine Series 606 $aInternal medicine 606 $aOncogenic viruses 606 $aInternal Medicine 606 $aTumour Virus Infections 606 $aVirus de l'hepatitis B$2thub 606 $aMalalties del fetge$2thub 608 $aLlibres electrònics$2thub 615 0$aInternal medicine. 615 0$aOncogenic viruses. 615 14$aInternal Medicine. 615 24$aTumour Virus Infections. 615 7$aVirus de l'hepatitis B 615 7$aMalalties del fetge 676 $a616.3623 702 $aKao$b Jia-Horng 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910494563403321 996 $aHepatitis B Virus and Liver Disease$92555165 997 $aUNINA