LEADER 05905nam 22009015 450 001 9910484907103321 005 20251226200227.0 010 $a1-280-90212-4 010 $a9786610902125 010 $a3-540-48540-6 024 7 $a10.1007/978-3-540-48540-7 035 $a(CKB)1000000000284021 035 $a(SSID)ssj0000310932 035 $a(PQKBManifestationID)11232994 035 $a(PQKBTitleCode)TC0000310932 035 $a(PQKBWorkID)10290173 035 $a(PQKB)10335444 035 $a(DE-He213)978-3-540-48540-7 035 $a(MiAaPQ)EBC3036645 035 $a(MiAaPQ)EBC6414077 035 $a(PPN)123139465 035 $a(BIP)46036442 035 $a(BIP)13973015 035 $a(EXLCZ)991000000000284021 100 $a20100301d2006 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aSystems Biology and Regulatory Genomics $eJoint Annual RECOMB 2005 Satellite Workshops on Systems Biology and on Regulatory Genomics, San Diego, CA, USA, December 2-4, 2005, Revised Selected Papers /$fedited by Eleazar Eskin, Trey Ideker, Ben Raphael, Christopher Workman 205 $a1st ed. 2006. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2006. 215 $a1 online resource (X, 261 p.) 225 1 $aLecture Notes in Bioinformatics,$x2366-6331 ;$v4023 300 $aIncludes index. 311 08$a3-540-48293-8 320 $aIncludes bibliographical references and index. 327 $aAn Interactive Map of Regulatory Networks of Pseudomonas aeruginosa Genome -- The Pathalyzer: A Tool for Analysis of Signal Transduction Pathways -- Decomposition of Overlapping Protein Complexes: A Graph Theoretical Method for Analyzing Static and Dynamic Protein Associations -- Comparison of Protein-Protein Interaction Confidence Assignment Schemes -- Characterization of the Effects of TF Binding Site Variations on Gene Expression Towards Predicting the Functional Outcomes of Regulatory SNPs -- Comparative Systems Biology of the Sporulation Initiation Network in Prokaryotes -- Improvement of Computing Times in Boolean Networks Using Chi-square Tests -- Build a Dictionary, Learn a Grammar, Decipher Stegoscripts, and Discover Genomic Regulatory Elements -- Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes -- Examination of the tRNA Adaptation Index as a Predictor of Protein Expression Levels -- Improved Duplication Models for Proteome Network Evolution -- Application of Expectation Maximization Clustering to Transcription Factor Binding Positions for cDNA Microarray Analysis -- Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data -- Topological Robustness of the Protein-Protein Interaction Networks -- A Bayesian Approach for Integrating Transcription Regulation and Gene Expression: Application to Saccharomyces Cerevisiae Cell Cycle Data -- Probabilistic in Silico Prediction of Protein-Peptide Interactions -- Improved Pattern-Driven Algorithms for Motif Finding in DNA Sequences -- Annotation of Promoter Regions in Microbial Genomes Based on DNA Structural and Sequence Properties -- An Interaction-Dependent Model for Transcription Factor Binding -- Computational Characterization and Identification of Core Promotersof MicroRNA Genes in C. elegans, H. sapiens and A. thaliana -- A Comprehensive Kinetic Model of the Exocytotic Process: Evaluation of the Reaction Mechanism. 330 $aThis book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2005 satellite events - the First Annual Workshop on Systems Biology, RSB 2005, and the Second Annual Workshop on Regulatory Genomics, RRG 2005, held in San Diego, CA, USA in December 2005. The 23 revised full papers presented were carefully reviewed and selected for inclusion in the book. The papers address a broad variety of topics in systems biology and regulatory genomics including inference of gene regulatory and protein signaling networks, model prediction of drug mechanism, pathway mapping and evolution in protein interaction networks, multi-scale methods which bridge abstract and detailed models, systematic design of genome-scale experiments, modeling and recognition of regulatory elements, identification and modeling of cis-regulatory regions, modeling the structure and function of the regulatory region, and comparative genomics of regulation. 410 0$aLecture Notes in Bioinformatics,$x2366-6331 ;$v4023 606 $aBiochemistry 606 $aAlgorithms 606 $aComputer science$xMathematics 606 $aDiscrete mathematics 606 $aArtificial intelligence$xData processing 606 $aDatabase management 606 $aBioinformatics 606 $aBiochemistry 606 $aAlgorithms 606 $aDiscrete Mathematics in Computer Science 606 $aData Science 606 $aDatabase Management 606 $aBioinformatics 615 0$aBiochemistry. 615 0$aAlgorithms. 615 0$aComputer science$xMathematics. 615 0$aDiscrete mathematics. 615 0$aArtificial intelligence$xData processing. 615 0$aDatabase management. 615 0$aBioinformatics. 615 14$aBiochemistry. 615 24$aAlgorithms. 615 24$aDiscrete Mathematics in Computer Science. 615 24$aData Science. 615 24$aDatabase Management. 615 24$aBioinformatics. 676 $a572.865 702 $aEskin$b Eleazar 712 12$aRECOMB Satellite Workshop on Systems Biology$f(2005 :$eSan Diego, Calif.) 712 12$aRECOMB Satellite Workshop on Regulatory Genomics. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484907103321 996 $aSystems Biology and Regulatory Genomics$9772143 997 $aUNINA