LEADER 02973nam 2200565 450 001 9910484652503321 005 20230630111219.0 010 $a3-030-67403-7 024 7 $a10.1007/978-3-030-67403-8 035 $a(CKB)4100000011930441 035 $a(DE-He213)978-3-030-67403-8 035 $a(MiAaPQ)EBC6627551 035 $a(Au-PeEL)EBL6627551 035 $a(OCoLC)1255225151 035 $a(PPN)255881673 035 $a(EXLCZ)994100000011930441 100 $a20220122d2021 uy 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aInflammation and epilepsy $enew vistas /$fDamir Janigro, Astrid Nehlig, Nicola Marchi, editors 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$d©2021 215 $a1 online resource (VII, 237 p. 19 illus., 17 illus. in color.) 225 1 $aProgress in Inflammation Research ;$v88 311 $a3-030-67402-9 327 $aPro and Anti-Inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium -- Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders -- Glial Mechanisms of Inflammation during Seizures -- Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy -- Blood T cells and Cytokine Levels during Interictal-Ictal Transitions -- Autoantibodies, Encephalopathies and Epilepsy -- Tau Protein in Drug-Resistant Epilepsy and Cognitive Decline -- Ketogenic Diet, Inflammation and Epilepsy -- Role of Regulatory T cells in Epilepsy -- Inflammation at the Neurovascular Unit in Post-Traumatic Epilepsy. 330 $aThis book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways. 410 0$aPIR (Series) ; 88. 606 $aEpilepsy 606 $aInflamació$2thub 606 $aEpilèpsia$2thub 608 $aLlibres electrònics$2thub 615 0$aEpilepsy. 615 7$aInflamació 615 7$aEpilèpsia 676 $a616.853 702 $aJanigro$b Damir 702 $aNehlig$b Astrid 702 $aMarchi$b Nicola 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484652503321 996 $aInflammation and epilepsy$92583231 997 $aUNINA