LEADER 03738nam 2200613 450 001 9910484526703321 005 20230522095743.0 010 $a3-030-55920-3 024 7 $a10.1007/978-3-030-55920-5 035 $a(CKB)4100000011797530 035 $a(DE-He213)978-3-030-55920-5 035 $a(MiAaPQ)EBC6516174 035 $a(Au-PeEL)EBL6516174 035 $a(OCoLC)1245666109 035 $a(PPN)254720714 035 $a(EXLCZ)994100000011797530 100 $a20211009d2021 uy 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$a5-ht2b receptors $efrom molecular biology to clinical applications /$fedited by Luc Maroteaux, Laurent Monassier 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$d©2021 215 $a1 online resource (VIII, 401 p. 44 illus.) 225 1 $aThe Receptors,$x1048-6909 ;$v35 311 $a3-030-55919-X 320 $aIncludes bibliographical references and index. 327 $aGene structure, expression, and 5-HT2B receptor signaling.-Serotonin function during embryonic development: the 5-HT2B receptor contribution -- Stem cells to decipher the physiological roles of 5-HT2B receptor signaling.-The serotonergic system in hematopoiesis and hematopoietic disorders -- The 5-HT2B receptor, the immune system and neuroinflammation.-5-HT2B Receptor on Macrophages: What for?.-Bone and 2B Serotonin receptor.-Roles of 5-HT2B receptor in pain -- 5-HT2B receptor, the heart and blood vessels.-5-HT2B receptor in Cardiopulmonary Disease -- Serotonin and cardiac Valves Degeneration in dog -- The discovery of 5-HT2B receptor pharmacology through the understanding of drug- induced valvulopathy -- Serotonin and fibrosis -- 5-HT2B receptors in liver -- Metabolic Regulation: Insulin secretion and action -- Drugs of abuse affecting 5-HT2B receptors.-The Role of 5-HT2B receptor on Aggression and Drugs of Abuse -- Role of the serotonin 2B receptor in the reinforcing effects of psychostimulants -- Serotonin 2B receptor interactions with dopamine network: implications for therapeutics in schizophrenia -- A Role for the 5-HT2B receptor in the Neurobiology of Schizophrenia -- 5-HT2B receptors and antidepressants -- Serotonin and the 5-HT2B receptor in amyotrophic lateral sclerosis. 330 $aThis contributed volume provides a comprehensive assessment of the roles played by 5-HT2B receptors in humans. These receptors have been shown to play an important role is the cardiac, intestinal, and central nervous systems as well as in bone marrow formation and growth. In this book, expert researchers present their findings on molecular and physiological/pathological aspects of 5-HT2B receptors. The molecular section includes a discussion of the genetics of 5-HT2B receptors and impulse control. The physiological section covers their role in many biological systems including the nervous system, the heart, and the lungs. 410 0$aThe Receptors,$x1048-6909 ;$v35 606 $aNeurosciences 606 $aHuman physiology 606 $aReceptors de serotonina$2thub 606 $aFisiologia humana$2thub 606 $aNeurociències$2thub 608 $aLlibres electrònics$2thub 615 0$aNeurosciences. 615 0$aHuman physiology. 615 7$aReceptors de serotonina 615 7$aFisiologia humana 615 7$aNeurociències 676 $a612.8042 702 $aMaroteaux$b Luc 702 $aMonassier$b Laurent 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484526703321 996 $a5-ht2b receptors$91905768 997 $aUNINA