LEADER 02583oam 2200493 450 001 9910484521403321 005 20210515125432.0 010 $a3-030-62565-6 024 7 $a10.1007/978-3-030-62565-8 035 $a(CKB)4100000011610243 035 $a(MiAaPQ)EBC6407557 035 $a(DE-He213)978-3-030-62565-8 035 $a(EXLCZ)994100000011610243 100 $a20210515d2021 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOnce can be enough $edecisive experiments, no replication required /$fAllan Franklin, Ronald L. Laymon 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$d©2021 215 $a1 online resource (XII, 181 p. 51 illus.) 311 $a3-030-62564-8 327 $aIntroduction -- The Meselson-Stahl Experiment: ?The Most Beautiful Experiment in Biology? -- The Discovery of the Positron -- The Discovery of the Omega Minus Hyperon -- Once Should Have Been Enough: Gregor Mendel, ?Experiments in Plant Hybridization? -- Once Came Close To Being Enough: Electron Polarization and Parity Nonconservation -- The Discovery of Parity Nonconservation -- The Search for the Magnetic Monopole -- Conclusion. 330 $aThere has recently been considerable discussion of a ?replication crisis? in some areas of science. In this book, the authors argue that replication is not a necessary criterion for the validation of a scientific experiment. Five episodes from physics and genetics are used to substantiate this thesis: the Meselson-Stahl experiment on DNA replication, the discoveries of the positron and the omega minus hyperon, Mendel?s plant experiments, and the discovery of parity nonconservation. Two cases in which once wasn?t enough are also discussed, the nondiscovery of parity nonconservation and the search for magnetic monopoles. Reasons why once wasn?t enough are also discussed. 606 $aReplication (Experimental design) 606 $aScience$xExperiments$xHistory 606 $aScience$xExperiments 608 $aElectronic books. 615 0$aReplication (Experimental design) 615 0$aScience$xExperiments$xHistory. 615 0$aScience$xExperiments. 676 $a507.2 700 $aFranklin$b Allan$f1938-$052578 702 $aLaymon Ronald L 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bUtOrBLW 906 $aBOOK 912 $a9910484521403321 996 $aOnce can be enough$92847258 997 $aUNINA LEADER 00882nam0-22002771i-450 001 990005400780403321 005 20240220111519.0 035 $a000540078 035 $aFED01000540078 035 $a(Aleph)000540078FED01 035 $a000540078 100 $a19990530d1959----km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $a<>"castellaro" dell'eta del Ferro sopra Sestri Ponente$fGiuseppe Isetti 210 $a[Genova]$cIstituto Internazionale di Studi Liguri$d1959 215 $a2 p.$d29 cm 300 $aEstratto da.: "Studi Genuensi", 2, 1958-1959 700 1$aIsetti,$bGiuseppe$0207674 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990005400780403321 952 $aARCH. BM MISC. 158 (14)$bARCH. 14956$fFLFBC 959 $aFLFBC 996 $a"castellaro" dell'eta del Ferro sopra Sestri Ponente$9595713 997 $aUNINA LEADER 00960nam0 22002531i 450 001 UON00063985 005 20231205102321.530 100 $a20020107d1967 |0itac50 ba 101 $aurd 102 $aPK 105 $a|||| 1|||| 200 1 $aMasnavi Zahr-e Cisq aur us ke Naqqad$fMuhammad Hasan 210 $aKarachi$cMatbu'atu'l-Hasan$d1967 215 $a135 p.$d19 cm 620 $aPK$dKarachi$3UONL000094 686 $aSI VI DA$cSubcontinente indiano - Letteratura Urdu - Critica$2A 700 1$aHASAN$bMuhammad$3UONV016182$0656222 712 $aMatbu'atu'l-Hasan$3UONV256315$4650 801 $aIT$bSOL$c20250711$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00063985 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI SI VI DA 174 $eSI IND572 5 174 996 $aMasnavi Zahr-e Cisq aur us ke Naqqad$91171546 997 $aUNIOR