LEADER 03241nam 2200505 450 001 9910484471603321 005 20210324151035.0 010 $a3-030-61663-0 024 7 $a10.1007/978-3-030-61663-2 035 $a(CKB)4100000011746955 035 $a(DE-He213)978-3-030-61663-2 035 $a(MiAaPQ)EBC6469432 035 $a(PPN)253862450 035 $a(EXLCZ)994100000011746955 100 $a20210324d2021 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCannabinoids and sleep $emolecular, functional and clinical aspects /$fJaime M. Monti, S. R. Pandi-Perumal, Eric Murillo-Rodriguez, editors 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$dİ2021 215 $a1 online resource (XXII, 181 p. 37 illus., 21 illus. in color.) 225 1 $aAdvances in experimental medicine and biology ;$vVolume 1297 311 $a3-030-61662-2 327 $aConstituents of Cannabis Sativa -- Synthetic and Natural Derivatives of Cannabidiol -- Clinical Pharmacokinetics of Cannabinoids and Potential Drug-Drug Interactions -- Cannabinoid Receptors and Ligands: Lessions from CNS Disorders and the Quest for Novel Treatment Venues -- Sleep-Wake Neurobiology -- Cannabinoids and Sleep/Wake Control -- Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals -- Modulation of Noradrenergic and Serotonergic Systems by Cannabinoids: Electrophysiological, Neurochemical and Behavioral Evidence -- Natural Cannabinoids as Templates for Sleep Disturbances Treatment -- The Effect of Cannabinoids on the Brain´s Circadian Clock -- Effects of Cannabis Consumption on Sleep -- Addiction and Sleep Disorders -- Cannabis for Restless Legs Syndrome. 330 $aResearch on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology. 410 0$aAdvances in experimental medicine and biology ;$vVolume 1297. 606 $aMolecular biology 606 $aNeurosciences 615 0$aMolecular biology. 615 0$aNeurosciences. 676 $a572.8 702 $aMonti$b Jaime M. 702 $aPandi-Perumal$b S. R. 702 $aMurillo-Rodri?guez$b Eric 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484471603321 996 $aCannabinoids and sleep$92803919 997 $aUNINA