LEADER 05806nam 22008175 450 001 9910484447203321 005 20200702213403.0 010 $a3-642-04744-0 024 7 $a10.1007/978-3-642-04744-2 035 $a(CKB)1000000000784704 035 $a(SSID)ssj0000316718 035 $a(PQKBManifestationID)11246847 035 $a(PQKBTitleCode)TC0000316718 035 $a(PQKBWorkID)10275020 035 $a(PQKB)10849324 035 $a(DE-He213)978-3-642-04744-2 035 $a(MiAaPQ)EBC3064631 035 $a(PPN)139958932 035 $a(EXLCZ)991000000000784704 100 $a20100301d2009 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aComparative Genomics $eInternational Workshop, RECOMB-CG 2009, Budapest, Hungary, September 27-29, 2009, Proceedings /$fedited by Francesca D. Ciccarelli, István Miklós 205 $a1st ed. 2009. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2009. 215 $a1 online resource (VIII, 241 p.) 225 1 $aLecture Notes in Bioinformatics ;$v5817 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-642-04743-2 320 $aIncludes bibliographical references and index. 327 $aYeast Ancestral Genome Reconstructions: The Possibilities of Computational Methods -- Natural Parameter Values for Generalized Gene Adjacency -- Parking Functions, Labeled Trees and DCJ Sorting Scenarios -- Counting All DCJ Sorting Scenarios -- Minimal Conflicting Sets for the Consecutive Ones Property in Ancestral Genome Reconstruction -- Finding Nested Common Intervals Efficiently -- DCJ Median Problems on Linear Multichromosomal Genomes: Graph Representation and Fast Exact Solutions -- Rearrangement Models and Single-Cut Operations -- Aligning Two Genomic Sequences That Contain Duplications -- Inferring the Recent Duplication History of a Gene Cluster -- Pseudo Boolean Programming for Partially Ordered Genomes -- Computing the Summed Adjacency Disruption Number between Two Genomes with Duplicate Genes Using Pseudo-Boolean Optimization -- Reconstructing Histories of Complex Gene Clusters on a Phylogeny -- Co-evolutionary Models for Reconstructing Ancestral Genomic Sequences: Computational Issues and Biological Examples -- Whole-Genome Analysis of Gene Conversion Events -- A Statistically Fair Comparison of Ancestral Genome Reconstructions, Based on Breakpoint and Rearrangement Distances -- Comparative Genomics and Extensive Recombinations in Phage Communities -- Properties of Sequence Conservation in Upstream Regulatory and Protein Coding Sequences among Paralogs in Arabidopsis thaliana -- Transcription Factor Binding Probabilities in Orthologous Promoters: An Alignment-Free Approach to the Inference of Functional Regulatory Targets. 330 $aThis book constitutes the proceedings of the 7th RECOMB International Satellite Workshop on Comparative Genomics, RECOMB-CG 2009, Budapest, Hungary, in September 2009. This workshop is devoted to bringing together scientists working on all aspects of comparative genomics, from computer scientists, mathematicians and statisticians working on novel computational approaches for genome analysis and comparison, to biologists applying these computational tools to study the structure and the evolution of prokaryotic and eukaryotic genomes. The 19 papers presented were carefully reviewed and selected from 31 submissions. The papers illustrate the crucial role of comparative genomics in understanding genome function and address a broad variety of aspects, ranging from the inference of evolution in genetic regulatory networks to the divergent fates of gene and genome duplication events and to the importance of new computational approaches to unraveling the structural evolution of genomes. 410 0$aLecture Notes in Bioinformatics ;$v5817 606 $aLife sciences 606 $aBioinformatics 606 $aBioinformatics  606 $aComputational biology  606 $aComputer science?Mathematics 606 $aLife Sciences, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L00004 606 $aComputational Biology/Bioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23050 606 $aComputer Appl. in Life Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/L17004 606 $aBioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15001 606 $aSymbolic and Algebraic Manipulation$3https://scigraph.springernature.com/ontologies/product-market-codes/I17052 606 $aDiscrete Mathematics in Computer Science$3https://scigraph.springernature.com/ontologies/product-market-codes/I17028 608 $aBudapest (2009)$2swd 608 $aKongress.$2swd 615 0$aLife sciences. 615 0$aBioinformatics. 615 0$aBioinformatics . 615 0$aComputational biology . 615 0$aComputer science?Mathematics. 615 14$aLife Sciences, general. 615 24$aComputational Biology/Bioinformatics. 615 24$aComputer Appl. in Life Sciences. 615 24$aBioinformatics. 615 24$aSymbolic and Algebraic Manipulation. 615 24$aDiscrete Mathematics in Computer Science. 676 $a570 686 $aBIO 110f$2stub 686 $aBIO 180f$2stub 686 $aSS 4800$2rvk 702 $aCiccarelli$b Francesca D$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMiklós$b István$4edt$4http://id.loc.gov/vocabulary/relators/edt 712 12$aRECOMB-CG 2009 906 $aBOOK 912 $a9910484447203321 996 $aComparative Genomics$92849938 997 $aUNINA