LEADER 04888nam 2200709Ia 450 001 9910484447203321 005 20200520144314.0 010 $a3-642-04744-0 024 7 $a10.1007/978-3-642-04744-2 035 $a(CKB)1000000000784704 035 $a(SSID)ssj0000316718 035 $a(PQKBManifestationID)11246847 035 $a(PQKBTitleCode)TC0000316718 035 $a(PQKBWorkID)10275020 035 $a(PQKB)10849324 035 $a(DE-He213)978-3-642-04744-2 035 $a(MiAaPQ)EBC3064631 035 $a(PPN)139958932 035 $a(EXLCZ)991000000000784704 100 $a20091007d2009 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aComparative genomics $einternational workshop, RECOMB-CG 2009, Budapest, Hungary, September 27-29, 2009 : proceedings /$fFrancesca D. Ciccarelli, Istvan Miklos (eds.) 205 $a1st ed. 2009. 210 $aBerlin ;$aNew York $cSpringer$dc2009 215 $a1 online resource (VIII, 241 p.) 225 1 $aLecture notes in computer science,$x0302-9743 ;$v5817.$aLecture notes in bioinformatics 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-642-04743-2 320 $aIncludes bibliographical references and index. 327 $aYeast Ancestral Genome Reconstructions: The Possibilities of Computational Methods -- Natural Parameter Values for Generalized Gene Adjacency -- Parking Functions, Labeled Trees and DCJ Sorting Scenarios -- Counting All DCJ Sorting Scenarios -- Minimal Conflicting Sets for the Consecutive Ones Property in Ancestral Genome Reconstruction -- Finding Nested Common Intervals Efficiently -- DCJ Median Problems on Linear Multichromosomal Genomes: Graph Representation and Fast Exact Solutions -- Rearrangement Models and Single-Cut Operations -- Aligning Two Genomic Sequences That Contain Duplications -- Inferring the Recent Duplication History of a Gene Cluster -- Pseudo Boolean Programming for Partially Ordered Genomes -- Computing the Summed Adjacency Disruption Number between Two Genomes with Duplicate Genes Using Pseudo-Boolean Optimization -- Reconstructing Histories of Complex Gene Clusters on a Phylogeny -- Co-evolutionary Models for Reconstructing Ancestral Genomic Sequences: Computational Issues and Biological Examples -- Whole-Genome Analysis of Gene Conversion Events -- A Statistically Fair Comparison of Ancestral Genome Reconstructions, Based on Breakpoint and Rearrangement Distances -- Comparative Genomics and Extensive Recombinations in Phage Communities -- Properties of Sequence Conservation in Upstream Regulatory and Protein Coding Sequences among Paralogs in Arabidopsis thaliana -- Transcription Factor Binding Probabilities in Orthologous Promoters: An Alignment-Free Approach to the Inference of Functional Regulatory Targets. 330 $aThis book constitutes the proceedings of the 7th RECOMB International Satellite Workshop on Comparative Genomics, RECOMB-CG 2009, Budapest, Hungary, in September 2009. This workshop is devoted to bringing together scientists working on all aspects of comparative genomics, from computer scientists, mathematicians and statisticians working on novel computational approaches for genome analysis and comparison, to biologists applying these computational tools to study the structure and the evolution of prokaryotic and eukaryotic genomes. The 19 papers presented were carefully reviewed and selected from 31 submissions. The papers illustrate the crucial role of comparative genomics in understanding genome function and address a broad variety of aspects, ranging from the inference of evolution in genetic regulatory networks to the divergent fates of gene and genome duplication events and to the importance of new computational approaches to unraveling the structural evolution of genomes. 410 0$aLecture notes in computer science ;$v5817. 410 0$aLecture notes in computer science.$pLecture notes in bioinformatics. 517 3 $aRECOMB-CG 2009 606 $aBioinformatics$vCongresses 606 $aComputational biology$vCongresses 606 $aGene mapping$xStatistical methods$vCongresses 606 $aGenomics$vCongresses 606 $aPhysiology, Comparative$vCongresses 615 0$aBioinformatics 615 0$aComputational biology 615 0$aGene mapping$xStatistical methods 615 0$aGenomics 615 0$aPhysiology, Comparative 676 $a570 686 $aBIO 110f$2stub 686 $aBIO 180f$2stub 686 $aSS 4800$2rvk 701 $aCiccarelli$b Francesca D$01756281 701 $aMiklos$b Istvan$01756282 712 12$aRECOMB-CG 2009 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484447203321 996 $aComparative genomics$94193485 997 $aUNINA