LEADER 02804nam 2200505 450 001 9910484315203321 005 20210227105304.0 010 $a981-15-8327-7 024 7 $a10.1007/978-981-15-8327-8 035 $a(CKB)4100000011493406 035 $a(DE-He213)978-981-15-8327-8 035 $a(MiAaPQ)EBC6370532 035 $a(PPN)25830491X 035 $a(EXLCZ)994100000011493406 100 $a20210227d2021 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDevelopment of implantable electronics as novel approaches to obstructive sleep apnea /$fJungmin Seo 205 $a1st ed. 2021. 210 1$aSingapore :$cSpringer,$d[2021] 210 4$dİ2021 215 $a1 online resource (XVII, 75 p. 46 illus., 34 illus. in color.) 225 1 $aSpringer theses 300 $a"Doctoral thesis accepted by Seoul National University, Korea." 311 $a981-15-8326-9 320 $aIncludes bibliographical references. 327 $aIntroduction -- Methods -- Results -- Discussions -- Conclusion. . 330 $aThis book addresses novel methods to treat a very popular disease, obstructive sleep apnea, based on a knowledge of an electrical engineering. Two approaches are given in the book using an upper-airway stimulation based on the pathogenesis of an obstructive sleep apnea. Implantable electronics are devised to control the tongue and the soft palate considering that they are the major pharyngeal muscles contributing to the apnea. First, for tongue control, a cuff electrode was designed and fabricated to stimulate the hypoglossal nerve, which innervates to the tongue muscle. Rare-earth magnets were embedded in the cuff for easy and repeatable installation of the electrode. For soft palate control, a palatal implant system was firstly developed to contract the soft palate muscle by applying electrical stimuli. Comprised of an implant, an intra-oral device, and an external controller, the palatal implant system is fully powered and controlled by means of wireless communication. The approaches were demonstrated in both in vitro and in vivo assessments, in collaboration with department of Otorhinolaryngology, Seoul National University Bundang Hospital. . 410 0$aSpringer theses. 606 $aSleep apnea syndromes 606 $aBiomedical engineering 615 0$aSleep apnea syndromes. 615 0$aBiomedical engineering. 676 $a616.209 700 $aSeo$b Jungmin$01226661 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484315203321 996 $aDevelopment of implantable electronics as novel approaches to obstructive sleep apnea$92848234 997 $aUNINA