LEADER 03144nam 22005895 450 001 9910254143703321 005 20250609110049.0 010 $a3-319-54709-7 024 7 $a10.1007/978-3-319-54709-1 035 $a(CKB)3710000001100891 035 $a(DE-He213)978-3-319-54709-1 035 $a(MiAaPQ)EBC4822616 035 $a(PPN)199768277 035 $a(MiAaPQ)EBC6237377 035 $a(EXLCZ)993710000001100891 100 $a20170314d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFrederick Sanger $eTwo-Time Nobel Laureate in Chemistry /$fby Joe S. Jeffers 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (XI, 88 p. 70 illus., 23 illus. in color.) 225 1 $aHistory of Chemistry,$x2212-991X 311 08$a3-319-54707-0 320 $aIncludes bibliographical references and index. 327 $aIntroduction -- Early Life 1918-1943 -- Protein Period 1943-1962 -- Origins of the Medical Research Council Laboratory of Molecular Biology.- RNA Period 1962-1971 -- DNA Period 1969-1983 -- Life outside the Lab -- The Man and His Legacy. 330 $aIn this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger?s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger?s remarkable career, Jeffers describes Sanger?s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger?s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson. 410 0$aHistory of Chemistry,$x2212-991X 606 $aBioorganic chemistry 606 $aHistory 606 $aProteins 606 $aBioorganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19010 606 $aHistory of Science$3https://scigraph.springernature.com/ontologies/product-market-codes/731000 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 615 0$aBioorganic chemistry. 615 0$aHistory. 615 0$aProteins. 615 14$aBioorganic Chemistry. 615 24$aHistory of Science. 615 24$aProtein Science. 676 $a540 700 $aJeffers$b Joe S$4aut$4http://id.loc.gov/vocabulary/relators/aut$0767209 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254143703321 996 $aFrederick Sanger$91561801 997 $aUNINA LEADER 03800nam 22007815 450 001 9910484230403321 005 20251226203027.0 010 $a3-540-87536-0 024 7 $a10.1007/978-3-540-87536-9 035 $a(CKB)1000000000490345 035 $a(SSID)ssj0000715580 035 $a(PQKBManifestationID)11468966 035 $a(PQKBTitleCode)TC0000715580 035 $a(PQKBWorkID)10703156 035 $a(PQKB)11126973 035 $a(DE-He213)978-3-540-87536-9 035 $a(MiAaPQ)EBC3063389 035 $a(MiAaPQ)EBC6283301 035 $a(PPN)12906291X 035 $a(EXLCZ)991000000000490345 100 $a20100301d2008 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aArtificial Neural Networks - ICANN 2008 $e18th International Conference, Prague, Czech Republic, September 3-6, 2008, Proceedings Part I /$fedited by Jan Koutnik, Vera Kurkova-Pohlova, Roman Neruda 205 $a1st ed. 2008. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2008. 215 $a1 online resource (XXIX, 1026 p.) 225 1 $aTheoretical Computer Science and General Issues,$x2512-2029 ;$v5163 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a3-540-87535-2 320 $aIncludes bibliographical references and author index. 327 $aMathematical Theory of Neurocomputing -- Learning Algorithms -- Kernel Methods, Statistical Learning, and Ensemble Techniques -- Support Vector Machines -- Reinforcement Learning -- Evolutionary Computing -- Hybrid Systems -- Self-organization -- Control and Robotics -- Signal and Time Series Processing -- Image Processing -- Image Processing ? Recognition Systems. 330 $aThis two volume set LNCS 5163 and LNCS 5164 constitutes the refereed proceedings of the 18th International Conference on Artificial Neural Networks, ICANN 2008, held in Prague Czech Republic, in September 2008. The 200 revised full papers presented were carefully reviewed and selected from more than 300 submissions. The first volume contains papers on mathematical theory of neurocomputing, learning algorithms, kernel methods, statistical learning and ensemble techniques, support vector machines, reinforcement learning, evolutionary computing, hybrid systems, self-organization, control and robotics, signal and time series processing and image processing. 410 0$aTheoretical Computer Science and General Issues,$x2512-2029 ;$v5163 606 $aArtificial intelligence 606 $aComputer science 606 $aNeurosciences 606 $aPattern recognition systems 606 $aApplication software 606 $aArtificial Intelligence 606 $aTheory of Computation 606 $aNeuroscience 606 $aAutomated Pattern Recognition 606 $aComputer and Information Systems Applications 615 0$aArtificial intelligence. 615 0$aComputer science. 615 0$aNeurosciences. 615 0$aPattern recognition systems. 615 0$aApplication software. 615 14$aArtificial Intelligence. 615 24$aTheory of Computation. 615 24$aNeuroscience. 615 24$aAutomated Pattern Recognition. 615 24$aComputer and Information Systems Applications. 676 $a006.32 702 $aKurkova-Pohlova$b Vera$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKoutnik$b Jan$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aNeruda$b Roman$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484230403321 996 $aArtificial Neural Networks - ICANN 2008$9774018 997 $aUNINA