LEADER 06427nam 22007455 450 001 9910484159603321 005 20230203070524.0 010 $a3-642-40708-0 024 7 $a10.1007/978-3-642-40708-6 035 $a(CKB)3710000000019149 035 $a(SSID)ssj0001010861 035 $a(PQKBManifestationID)11551950 035 $a(PQKBTitleCode)TC0001010861 035 $a(PQKBWorkID)11004090 035 $a(PQKB)10629420 035 $a(DE-He213)978-3-642-40708-6 035 $a(MiAaPQ)EBC3093029 035 $a(PPN)172429862 035 $a(EXLCZ)993710000000019149 100 $a20130918d2013 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aComputational Methods in Systems Biology $e11th International Conference, CMSB 2013, Klosterneuburg, Austria, September 22-24, 2013, Proceedings /$fedited by Ashutosh Gupta, Thomas A. Henzinger 205 $a1st ed. 2013. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2013. 215 $a1 online resource (XX, 284 p. 58 illus.) 225 1 $aLecture Notes in Bioinformatics,$x2366-6331 ;$v8130 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-642-40707-2 327 $aOn the Use of the Moment Equations for Parameter Inference, Control and Experimental Design in Stochastic Biochemical Reaction Networks -- Numerical Approximation of Rare Event Probabilities in Biochemically Reacting Systems -- An Approximate Execution of Rule-Based Multi-level Models -- Computing Cumulative Rewards Using Fast Adaptive Uniformisation -- Linking Discrete and Stochastic Models: The Chemical Master Equation as a Bridge between Process Hitting and Proper Generalized Decomposition -- Coarse-Grained Brownian Dynamics Simulation of Rule-Based Models -- Modelling and Analysis of Phase Variation in Bacterial Colony Growth -- Using Probabilistic Strategies to Formalize and Compare ?-Synuclein Aggregation and Propagation under Different Scenarios -- Dynamic Image-Based Modelling of Kidney Branching Morphogenesis -- Statistical Model Checking Based Calibration and Analysis of Bio-pathway Models -- Constraint Programming in Community-Based Gene Regulatory Network Inference -- ABC?Fun: A Probabilistic Programming Language for Biology -- A Temporal Logic Approach to Modular Design of Synthetic Biological Circuits -- A Lattice-Theoretic Framework for Metabolic Pathway Analysis -- On the Hybrid Composition and Simulation of Heterogeneous Biochemical Models -- On the Verification and Correction of Large-Scale Kinetic Models in Systems Biology -- Context-Sensitive Flow Analyses: A Hierarchy of Model Reductions -- Posters   Backmatter) -- ARNI: Abductive Inference of Complex Regulatory Network Structures -- A Systems Biology and Ecology Framework for POPs Bioaccumulation in Marine Ecosystems -- A Symbolic Approach Based on Model Checking and Constraint Solving Techniques for Reverse Engineering of Thomas Networks Parameters -- Compositionality Results for Cardiac Cell Dynamics -- Quantification of Biological Network Perturbations: Impact Assessment Using Causal Biological Networks -- Deciphering the Transcriptional Landscape of Caulobacter crescentus at Base Pair Resolution -- Identifiablity Analysis and Improved Parameter Estimation of a Human Blood Glucose Control System Model -- RNA Interference in Cancer and Cell Cycle Networks: A Case Study of E2F Proteins -- A Balancing Act: Parameter Estimation for Biological Models with Steady-State Measurements -- A Fusion Approach Linking Signaling Logic and Metabolic Mass-Flow Kinetics in Hepatocytes -- Esther: Introducing an Online Platform for Parameter Identification of Boolean Networks -- Identifying Latent Dynamic Components in Biological Systems -- Next-Newtomics: The Next Generation Repository for Bioinformatical Interpreted Omics Datasets from the Newt Notophthalmus viridescens -- MiRNA Expression Analysis during Heart Regeneration of N. viridescens -- Algorithm to Predict G-Quadruplex Folding through Score Computing -- Optimization Based Inference of Metabolic Networks from Metabolome Data -- PHISTO: A New Web Platform for Pathogen-Human Interactions -- Frameshift Correction in De Novo Assembled Transcriptome Data Using Peptide Data, Blast Sequence Alignments and Hidden Markov Models -- From Prokaryote Genome Sequencing to Pan-Genomic Modeling -- A Simulation Approach to Detect Oscillating Behaviour in Stochastic Population Models -- On Bistability Causing Structures in Escherichia Coli?s Metabolism -- Mathematical Modelling of the Function of Ubiquitylation in TNFR1-MediatedNF-?B Signalling -- Organizing SIV Gene Network Modules into Graph Database. 330 $aThis book constitutes the proceedings of the 11th International Conference on Computational Methods in Systems Biology, CMSB 2013, held in Klosterneuburg, Austria, in September 2013. The 15 regular papers included in this volume were carefully reviewed and selected from 27 submissions. They deal with computational models for all levels, from molecular and cellular, to organs and entire organisms. 410 0$aLecture Notes in Bioinformatics,$x2366-6331 ;$v8130 606 $aBioinformatics 606 $aComputer science 606 $aComputer simulation 606 $aSoftware engineering 606 $aComputer science?Mathematics 606 $aComputational and Systems Biology 606 $aTheory of Computation 606 $aComputer Modelling 606 $aSoftware Engineering 606 $aSymbolic and Algebraic Manipulation 615 0$aBioinformatics. 615 0$aComputer science. 615 0$aComputer simulation. 615 0$aSoftware engineering. 615 0$aComputer science?Mathematics. 615 14$aComputational and Systems Biology. 615 24$aTheory of Computation. 615 24$aComputer Modelling. 615 24$aSoftware Engineering. 615 24$aSymbolic and Algebraic Manipulation. 676 $a572.80285 702 $aGupta$b Ashutosh$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHenzinger$b Thomas A$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910484159603321 996 $aComputational Methods in Systems Biology$92907803 997 $aUNINA