LEADER 04758nam 22006734a 450 001 9910451688703321 005 20200520144314.0 010 $a1-281-86256-8 010 $a9786611862565 010 $a3-7643-8552-9 024 7 $a10.1007/978-3-7643-8552-1 035 $a(CKB)1000000000491476 035 $a(EBL)364338 035 $a(OCoLC)288473605 035 $a(SSID)ssj0000290243 035 $a(PQKBManifestationID)11234193 035 $a(PQKBTitleCode)TC0000290243 035 $a(PQKBWorkID)10409436 035 $a(PQKB)11253366 035 $a(DE-He213)978-3-7643-8552-1 035 $a(MiAaPQ)EBC364338 035 $a(PPN)128126450 035 $a(Au-PeEL)EBL364338 035 $a(CaPaEBR)ebr10245932 035 $a(CaONFJC)MIL186256 035 $a(EXLCZ)991000000000491476 100 $a20080124d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBone morphogenetic proteins$b[electronic resource] $efrom local to systemic therapeutics /$fSlobodan Vukicevic, Kuber T. Sampath, editors 205 $a1st ed. 2008. 210 $aBasel ;$aBoston $cBirkha?user$dc2008 215 $a1 online resource (348 p.) 225 1 $aProgress in inflammation research 300 $aDescription based upon print version of record. 311 $a3-7643-8551-0 320 $aIncludes bibliographical references and index. 327 $aDevelopment of a novel compression-resistant carrier for recombinant human bone morphogenetic protein-2 (rhBMP-2) and preliminary clinical results -- Use of recombinant human BMP-2 in orthopedic trauma -- The application of recombinant human bone morphogenetic protein on absorbable collagen sponge (rhBMP-2/ACS) to reconstruction of maxillofacial bone defects -- Clinical outcomes using rhBMP-2 in spinal fusion applications -- Bone morphogenetic protein signaling is fine-tuned on multiple levels -- Dissection of bone morphogenetic protein signaling using genome-engineering tools -- Alterations of BMP signaling pathway(s) in skeletal diseases -- Signaling cross-talk by bone morphogenetic proteins -- The role and mechanisms of bone morphogenetic protein 4 and 2 (BMP-4 and BMP-2) in postnatal skeletal development -- The role of bone morphogenetic protein 4 (BMP-4) in tooth development -- Bone morphogenetic protein antagonists and kidney -- Induction of cementogenesis and periodontal ligament regeneration by the bone morphogenetic proteins -- Control of bone mass by sclerostin: Inhibiting BMP- and WNT-induced bone formation -- Bone morphogenetic proteins in cartilage biology -- Systemic administration of bone morphogenetic proteins. 330 $aTissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs. In this volume, we summarize the advances made on the local and systemic use of BMPs including chapters covering the regulation of BMP-signalling pathways, biological actions of BMPs in bone, cartilage and teeth, as well as clinical applications and potential systemic use of BMPs for tissues beyond bone. This volume is of interest to researchers from immunology, cell biology, biochemistry, and clinicians from orthopedics and dentistry, as well as to research managers from biotech and pharmaceutical companies. 410 0$aPIR (Series) 606 $aBone morphogenetic proteins 606 $aBone morphogenetic proteins$xTherapeutic use 608 $aElectronic books. 615 0$aBone morphogenetic proteins. 615 0$aBone morphogenetic proteins$xTherapeutic use. 676 $a612.75 676 $a616.7/1061 701 $aVukicevic$b Slobodan$f1951-$01039570 701 $aSampath$b Kuber T$01039571 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451688703321 996 $aBone morphogenetic proteins$92461873 997 $aUNINA LEADER 06487oam 22008414a 450 001 996354143803316 005 20210915045639.0 010 $a0-8232-8733-5 024 7 $a10.1515/9780823287338 035 $a(CKB)4100000010105075 035 $a(DE-B1597)555015 035 $a(DE-B1597)9780823287338 035 $a(OCoLC)1129396968 035 $a(MiAaPQ)EBC5987168 035 $a(Au-PeEL)EBL5987168 035 $a(OCoLC)1142905880 035 $a(MdBmJHUP)muse82377 035 $a(EXLCZ)994100000010105075 100 $a20200228d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Letters of William Cullen Bryant$eVolume VI, 1872?1878 /$hVolume VI$i1872-1878 /$fedited by William Cullen Bryant II and Thomas G. Voss$i1872-1878 /$hVolume VI 205 $aFirst open access edition. 210 1$aBaltimore, Maryland :$cProject Muse,$d2020 210 4$d©2020 215 $a1 online resource (474 p.) $c9 300 $aOriginally published: 1992. 311 $a0-8232-0996-2 320 $aIncludes bibliographical references and indexes. 327 $tFrontmatter -- $tContents -- $tKey to Manuscript Sources Often Cited in Footnotes -- $tACKNOWLEDGMENTS -- $tBryant Chronology 1872-1878 -- $tBryant's Correspondents 1872-1878 -- $tXXXII. Mexico, and an Election 1872 -- $tXXXIII. Doctor of Laws 1873 -- $tXXXIV. Homage to an Octogenarian 1874 -- $tXXXV. Public Tributes 1875 -- $tXXXVI. An Agonizing Decision 1876 -- $tXXXVII. "Well of English Undefiled" 1877 -- $tXXXVIII .The Rights and Duties of Human Brotherhood 1878 -- $tAbbreviations and Short Titles -- $tIndex of Recipients. Volume VI -- $tIndex 330 $aOn April 26, 1865, as Abraham Lincoln's funeral cortege paused in Union Square, New York, before being taken by rail to Springfield, Illinois, William Cullen Bryant listened as his own verse elegy for the slain president was read to a great concourse of mourners by the Reverend Samuel Osgood. Only five years earlier and a few blocks downtown, at Cooper Union, Bryant had introduced the prairie candidate to his first eastern audience. There his masterful appeal to the conscience of the nation prepared the way for his election to the presidency on the verge of the Civil War. Now, Bryant stood below Henry Kirke Brown's equestrian statue of George Washington, impressing Osgood as if he were "the 19tth Century itself thinking over the nation and the age in that presence." Bryant's staunch support of the Union cause throughout the war, and of Lincoln's war efforts, no less than his known influence with the president, led several prominent public figures to urge that he write Lincoln's biography. Oliver Wendell Holmes wrote him, "No man combines the qualities for his biographer so completely as yourself and the finished task would be a noble crown to a noble literary life." But Bryant declined, declaring his inability to record impartially critical events in which he had taken so central a part. Furthermore, while preoccupied with the editorial direction of the New York Evening Post, he was just then repossessing and enlarging his family's homestead at Cummington, Massachusetts, where he hoped his ailing wife might, during long summers in mountain air, regain her health. But in July 1866, Frances died of recurrent rheumatic fever, and, Bryant confessed to Richard Dana, he felt as "one cast out of Paradise." After France's death Bryant traveled with his daughter Julia for nearly a year through Great Britain and the Continent, where he met British statesman and novelist Edward Bulwer Lytton and French literary critic Hyppolyte Taine, renewed his friendship with Spanish poet Carolina Coronado, Italian liberator Giuseppe Garibaldi, and British and American artists, and visited the family of the young French journalist Georges Clemenceau, as well as the graves of earlier acquaintances Francis Lord Jeffrey and Elizabeth Barrett Browning. In his spare moments Bryant sought solace by beginning the translation of Homer, and Longfellow had found relief after his wife's tragic death by rendering into English Dante's Divine Comedy. Home again in New York, Bryant bought and settled in a house at 24 West 16th Street which would be his city home for the rest of his life. Here he completed major publications, including the Iliad and Odyssey of Homer and an exhaustive Library of Poetry and Song, and added to published tributes to earlier friends, such as Thomas Cole, Fenimore Cooper, and Washington Irving, memorial discourses on Fitz-Greene Halleck and Gulian Verplanck. In addition to his continued direction of the New York Homeopathic Medical college and the American Free Trade League, he was elected to the presidency of the Williams College Alumni Association, the International Copyright Association, and the Century Association, the club of artists and writers of which, twenty years earlier, he had been a principal founder and which he would direct for the last decade of his life. 606 $aPoets, American$y19th century$vCorrespondence 608 $aElectronic books. 610 $aAmerican Library Association. 610 $aBryant Library. 610 $aCentral Park. 610 $aCummington, Massachusetts. 610 $aFitz-Greene Halleck. 610 $aGeorge Palmer Putnam. 610 $aGiuseppe Mazzini. 610 $aHorace Greeley. 610 $aJournalism. 610 $aLetters. 610 $aMexico City. 610 $aNew York City. 610 $aNew York Evening Post. 610 $aNew York Tribune. 610 $aOrations and Addresses. 610 $aPicturesque America. 610 $aPoetry. 610 $aPresident Benito Juarez. 610 $aPresidential Library. 610 $aPrinceton University. 610 $aRutherford Hayes. 610 $aSamuel Jones Tilden. 610 $aShakespeare. 610 $aState Charities Aid Association. 610 $aWalter Scott. 610 $aWilliam Cullen Bryant. 615 0$aPoets, American 676 $a811/.3 700 $aBryant$b William Cullen$f1794-1878,$0196361 701 $aVoss$b Thomas G$01022090 701 $aBryant$b William Cullen$f1908-1999.$01022091 801 0$bMdBmJHUP 801 1$bMdBmJHUP 906 $aBOOK 912 $a996354143803316 996 $aThe Letters of William Cullen Bryant$92427592 997 $aUNISA LEADER 11904 am 2203193 n 450 001 9910495994903321 005 20210721 010 $a979-1-280-13633-6 024 7 $a10.4000/books.aaccademia.8203 035 $a(CKB)4100000012014384 035 $a(FrMaCLE)OB-aaccademia-8203 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/87142 035 $a(EXLCZ)994100000012014384 100 $a20210903j|||||||| ||| 0 101 0 $aeng 135 $auu||||||m|||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aProceedings of the Seventh Italian Conference on Computational Linguistics CLiC-it 2020 $eBologna, Italy, March 1-3, 2021 /$fFelice Dell'Orletta, Johanna Monti, Fabio Tamburini 210 $aTorino $cAccademia University Press$d2021 215 $a1 online resource (487 p.) 225 1 $aCollana dell'Associazione Italiana di Linguistica Computazionale 330 $aOn behalf of the Program Committee, a very warm welcome to the Seventh Italian Conference on Computational Linguistics (CLiC-it 2020). This edition of the conference is held in Bologna and organised by the University of Bologna. The CLiC-it conference series is an initiative of the Italian Association for Computational Linguistics (AILC) which, after six years of activity, has clearly established itself as the premier national forum for research and development in the fields of Computational Linguistics and Natural Language Processing, where leading researchers and practitioners from academia and industry meet to share their research results, experiences, and challenges. 517 $aProceedings of the Seventh Italian Conference on Computational Linguistics CLiC-it 2020 606 $aLinguistics 606 $aComputational Linguistics 606 $aFine-grained sentiment analysis 606 $aDistributional Semantics 606 $aQuantitative Linguistic Investigations 606 $aGender Bias 606 $aDepression from Social Media 606 $aOnline Hate Speech 606 $aAutomatic Sarcasm Detection 606 $aTrAVaSI 606 $aAriEmozione 606 $aAEREST 606 $aCOVID-19 606 $aLinguistic Ostracism in Social Networks 606 $aMultilingual NLU 606 $aE3C Project 606 $aDistilBERT 606 $aTwitter 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Essential reading for anyone interested in Germany in Europe." --- Professor Hanns W. Maull, Senior Distinguished Fellow, German Institute for International and Security Affairs (SWP) "This book is highly recommended to anyone who wishes to understand how EU foreign policy emerges from the complex interaction between member states and EU institutions. I particularly hope it will find many readers in Russia, where experts and policy makers alike tend to frame Germany's changing role and policy in terms of traditional great power politics." --- Dr. Sabine Fischer, Team Leader, Public Diplomacy. EU and Russia project, Moscow This book contributes to the debate about a new German power in Europe with an analysis of Germany's role in European Russia policy. It provides an up-to-date account of Germany's "Ostpolitik" and how Germany has influenced EU-Russia relations since the Eastern enlargement in 2004 - partly along, partly against the interests and preferences of new member states. The volume combines a rich empirical analysis of Russia policy with a theory-based perspective on Germany's power and influence in the EU. The findings demonstrate that despite Germany's central role, exercising power within the EU is dependent on legitimacy and acceptance by other member states. Liana Fix is a historian and political scientist. In her work, she focuses on German foreign policy, Russia and Eastern Europe as well as European security and has published widely in academia, think tanks and national and international media. She completed a doctorate degree at the Justus Liebig University Giessen and a Master's degree at the London School of Economics and Political Science. 410 0$aNew Perspectives in German Political Studies,$x2947-6755 606 $aEurope$xPolitics and government 606 $aInternational relations 606 $aWorld politics 606 $aEuropean Politics 606 $aInternational Relations 606 $aForeign Policy 606 $aPolitical History 615 0$aEurope$xPolitics and government. 615 0$aInternational relations. 615 0$aWorld politics. 615 14$aEuropean Politics. 615 24$aInternational Relations. 615 24$aForeign Policy. 615 24$aPolitical History. 676 $a341.24220947 676 $a327.4047 700 $aFix$b Liana$0850483 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910483974203321 996 $aGermany's Role in European Russia Policy$91898845 997 $aUNINA