LEADER 03819oam 2200517 450 001 9910483953903321 005 20210529023240.0 010 $a3-030-58971-4 024 7 $a10.1007/978-3-030-58971-4 035 $a(OCoLC)1237357754 035 $a(CKB)5410000000054448 035 $a(MiAaPQ)EBC6417136 035 $a(DE-He213)978-3-030-58971-4 035 $a(PPN)252507533 035 $a(EXLCZ)995410000000054448 100 $a20210529d2021 uy 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMacromolecular protein complexes III $estructure and function /$fJ. Robin Harris, Jon Marles-Wright (editors) 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$d©2021 215 $a1 online resource (VIII, 577 p. 166 illus., 157 illus. in color.) 225 1 $aSubcellular Biochemistry,$x0306-0225 ;$v96 311 $a3-030-58970-6 320 $aIncludes bibliographical references. 327 $aChapter 1. Structure, Dynamics and Function of the 26S Proteasome -- Chapter 2. Factor VIII and Factor V Membrane Bound Complexes -- Chapter 3. An Overview of DPS: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties -- Chapter 4. Structure and Function of the Separase-Securin Complex -- Chapter 5. The DNA Replication Machine: Structure and Dynamic Function -- Chapter 6. Recent Progress in Structural Studies on the GT-C Superfamily of Protein Glycosyltransferases -- Chapter 7. How Structures of Complement Complexes Guide Therapeutic Design -- Chapter 8. Architecture and Assembly of the Bacterial Flagellar Motor Complex -- Chapter 9. Cellulosomes: Highly Efficient Cellulolytic Complexes -- Chapter 10. Leucine Dehydrogenase: Structure and Thermostability -- Chapter 11. Structure, Function and Physiology of 5-Hydroxytryptamine Receptors Subtype 3 -- Chapter 12. The SF3b Complex Is an Integral Component of the Spliceosome and Targeted by Natural Product-based Inhibitors -- Chapter 13. Interaction Networks of Ribosomal Expansion Segments in Kinetoplastids -- Chapter 14. Hepatitis B Core Protein Capsids -- Chapter 15. Fibrinogen and Fibrin -- Chapter 16. Structural Organization and Protein-protein Interactions in Human Adenovirus Capsid -- Chapter 17. A Structural Perspective on Gene Repression by Polycomb Repressive Complex 2 -- Chapter 18. Assembly and Function of the Anthrax Toxin Protein Translocation Complex. 330 $aThis book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein?protein interactions in the human adenovirus capsid, to mention but a few. The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License vialink.springer.com. 410 0$aSubcellular Biochemistry,$x0306-0225 ;$v96 517 3 $aMacromolecular protein complexes 3 517 3 $aMacromolecular protein complexes three 606 $aProteins$xStructure 615 0$aProteins$xStructure. 676 $a572.633 702 $aHarris$b J. Robin$g(James Robin), 702 $aMarles-Wright$b Jon 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bUtOrBLW 906 $aBOOK 912 $a9910483953903321 996 $aMacromolecular protein complexes III$92804507 997 $aUNINA