LEADER 01101nam a2200265 i 4500 001 991000872999707536 005 20020509180803.0 008 960614s1992 ||| ||| | ger 020 $a3923087195 035 $ab11422919-39ule_inst 035 $aPARLA217011$9ExL 040 $aDip.to scienze storiche$bita 082 0 $a271.1 100 1 $aBender, Wolfgang$0199682 245 10$aZisterzienser und stadte :$bstudien zu den Beziehungen zwischen den Zisterzienserklostern und den groben urbanen zentren des mittleren Moselraumes (12.-14. Jahrhundert) /$cWolfgang Bender 260 $aTrier :$bTHF,$c1992 300 $aXI, 402 p. ;$c24 cm. 490 0 $aTrierer historische forschungen / herausgegeben von Hans-Hubert Anton ... [et al.] ;$v20 610 24$aCistercensi$ySec. 12.-14. 907 $a.b11422919$b01-03-17$c01-07-02 912 $a991000872999707536 945 $aLE009 STOR.38-12$g1$i2009000028869$lle009$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i1161402x$z01-07-02 996 $aZisterzienser und stadte$9819181 997 $aUNISALENTO 998 $ale009$b01-01-96$cm$da $e-$feng$gxx $h0$i1 LEADER 00932nas 2200325-- 450 001 9910143792103321 005 20241216044001.0 035 $a(CKB)991042725958854 035 $a(CONSER)---77641910- 035 $a(EXLCZ)99991042725958854 100 $a20770901a19769999 --- a 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 200 00$aVia 210 $a[Berkeley, Calif.]$c[University of California, Berkeley] 215 $a1 online resource 311 08$aPrint version: Via. (DLC) 77641910 (OCoLC)3234853 0147-8184 606 $aLiterature$vPeriodicals 606 $aLiterature$2fast$3(OCoLC)fst00999953 608 $aPeriodicals.$2fast 615 0$aLiterature 615 7$aLiterature. 676 $a805 712 02$aUniversity of California, Berkeley. 906 $aJOURNAL 912 $a9910143792103321 920 $aexl_impl conversion 996 $aVia$9904003 997 $aUNINA LEADER 05281nam 2200685Ia 450 001 9911019614003321 005 20200520144314.0 010 $a9786611763985 010 $a9781281763983 010 $a1281763985 010 $a9783527612833 010 $a3527612831 010 $a9783527612840 010 $a352761284X 035 $a(CKB)1000000000377123 035 $a(EBL)482273 035 $a(OCoLC)261221906 035 $a(SSID)ssj0000222468 035 $a(PQKBManifestationID)11173248 035 $a(PQKBTitleCode)TC0000222468 035 $a(PQKBWorkID)10169544 035 $a(PQKB)11336229 035 $a(MiAaPQ)EBC482273 035 $a(Perlego)2773208 035 $a(EXLCZ)991000000000377123 100 $a20011203d2001 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPlasmids for therapy and vaccination /$fedited by M. Schleef 210 $aWeinheim ;$aNew York $cWiley-VCH$dc2001 215 $a1 online resource (308 p.) 300 $aDescription based upon print version of record. 311 08$a9783527302697 311 08$a3527302697 320 $aIncludes bibliographical references and index. 327 $aPlasmids for Therapy and Vaccination; Preface; Contents; List of Contributors; 1 The Biology of Plasmids; 1 Introduction: What are plasmids?; 2 General properties of plasmids; 2.1 Plasmid replication and its control; 2.2 The molecular basis of incompatibility; 2.3 Plasmid inheritance; 2.4 Mechanisms of plasmid spread; 2.4.1 Conjugation in gram-negative bacteria; 2.4.2 Conjugation in gram-positive bacteria; 3 Plasmid-encoded phenotypes; 3.1 Bacteriocin production and resistance; 3.2 The Ti plasmids; 3.3 Heavy metal resistance; 3.4 Other phenotypical traits 327 $a4 The clinical importance of plasmids4.1 The spread of antibiotic resistance and the evolution of multiple antibiotic resistance; 4.2 Transfer of antibiotic resistance genes; 4.3 Mechanisms of antibiotic resistance; 4.4 Bacterial virulence genes; 5 Plasmid cloning vectors; 6 Perspectives; References; 2 Structures of Plasmid DNA; 1 Introduction; 2 Topological structures of plasmids; 3 Supercoiling of DNA; 4 DNA intercalating dyes; 5 Analysis of plasmid structures; 5.1 Electron microscopy (EM); 5.2 Agarose gel electrophoresis (AGE); 5.3 Capillary gel electrophoresis (CGE) 327 $a5.4 Analytical chromatography6 Conclusion; References; 3 Genetic Vaccination with Plasmid Vectors; 1 Introduction; 2 Vector design; 2.1 Plasmid DNA; 2.2 Construction of simple transcription units; 2.3 Construction of complex transcription units; 3 Strategies for DNA delivery; 4 Priming humoral and cellular immune responses by DNA vaccines; 5 Experimental strategies facilitated by DNA vaccination; 6 Unique advantages of DNA vaccination; 7 DNA vaccines in preclinical animal models; 7.1 DNA vaccines to control infectious diseases; 7.2 Therapeutic tumor vaccines; 7.3 Autoimmune disease 327 $a7.4 Treatment of allergy by therapeutic DNA vaccination8 Proposed clinical applications of DNA vaccines; 9 Risks of nucleic acid vaccination; 10 Future perspectives; References; 4 A Liposomal iNOS-Gene Therapy Approach to Prevent Neointimal Lesion Formation in Porcine Femoral Arteries; 1 Introduction; 2 Results and discussion; 2.1 Therapeutic plasmid; 2.2 The gene therapy product has a clinically acceptable format; 2.3 Efficient gene transfer was established in a minipig femoral artery injury model; 2.4 Transfection efficiency is dose dependent 327 $a2.5 Non-viral iNOS gene transfer efficiently inhibits neointimal lesion formation3 Summary and perspectives; References; 5 lmmunotherapy of Chronic Hepatitis B by pCMV-S2.S DNA Vaccine; 1 Introduction; 1.1 Hepatitis B: the disease; 1.2 Hepatitis B: treatments; 1.3 Hepatitis B: immune response to infection; 1.4 What are DNA vaccines?; 1.5 Which DNA vaccines for hepatitis B?; 2 DNA vaccines for the prevention of hepatitis B; 2.1 The mouse model; 2.1.1 Humoral response; 2.1.2 Cell-mediated response; 2.1.3 Mechanisms of DNA-induced immune response to HBsAg; 2.1.4 The primate model 327 $a2.1.5 DNA-based vaccination of chimpanzees against HBV 330 $aThis is the first book specializing in plasmids and their biomedical use, including all relevant aspects of production, applications, quality, and regulations. Readers will discover clinical applications for the wide range of preventive and therapeutic applications using plasmid DNA. The book describes modified vector systems based on plasmids, as well as the potency of genomic research and vector design by informatics. Using the example of fish vaccination, the application of DNA vaccination in veterinary health care is reviewed, followed by a detailed overview of plasmid production technol 606 $aDNA vaccines 606 $aGene therapy 606 $aPlasmids 615 0$aDNA vaccines. 615 0$aGene therapy. 615 0$aPlasmids. 676 $a615/.3 701 $aSchleef$b M$g(Martin)$01663535 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019614003321 996 $aPlasmids for therapy and vaccination$94418471 997 $aUNINA LEADER 04448nam 2200805Ia 450 001 9910956380203321 005 20200520144314.0 010 $a9786610828135 010 $a9780905028057 010 $a0905028058 010 $a9781847699237 010 $a1847699235 010 $a9781280828133 010 $a1280828137 010 $a9781853596315 010 $a1853596310 024 7 $a10.21832/9781853596315 035 $a(CKB)111056487001918 035 $a(EBL)204122 035 $a(OCoLC)475918514 035 $a(SSID)ssj0000111474 035 $a(PQKBManifestationID)11124906 035 $a(PQKBTitleCode)TC0000111474 035 $a(PQKBWorkID)10075355 035 $a(PQKB)11281460 035 $a(DE-B1597)491409 035 $a(OCoLC)1046609558 035 $a(DE-B1597)9781853596315 035 $a(Au-PeEL)EBL204122 035 $a(CaPaEBR)ebr10051988 035 $a(CaONFJC)MIL82813 035 $a(MiAaPQ)EBC204122 035 $a(MiAaPQ)EBC31758998 035 $a(Au-PeEL)EBL31758998 035 $a(Perlego)571680 035 $a(EXLCZ)99111056487001918 100 $a20020909d2003 uy 0 101 0 $aeng 135 $aurnn#---|u||u 181 $ctxt 182 $cc 183 $acr 200 00$aBilingualism $ebeyond basic principles /$fedited by Jean-Marc Dewaele, Alex Housen, and Li Wei 205 $a1st ed. 210 $aClevedon ;$aBuffalo $cMultilingual Matters$dc2003 215 $a1 online resource (242 p.) 225 0 $aMultilingual Matters 300 $aIncludes index. 311 08$a9781853596254 311 08$a1853596256 311 08$a9781853596261 311 08$a1853596264 327 $tFront matter --$tContents --$tPreface --$tContributors --$tIntroduction and Overview --$t1. Who is Afraid of Bilingualism? --$t2. The Importance of Being Bilingual --$t3. Towards a More Language-centred Approach to Plurilingualism --$t4. Bilingual Education: Basic Principles --$t5. Bilingual Encounters in the Classroom --$t6. Language Planning: A Grounded Approach --$t7. Accepting Bilingualism as a Language Policy: An Unfolding Southeast Asian Story --$t8. Markets, Hierarchies and Networks in Language Maintenance and Language Shift --$t9. The Imagined Learner of Malay --$t10. Code-switching and Unbalanced Bilingualism --$t11. Code-switching: Evidence of Both Flexibility and Rigidity in Language --$t12. Rethinking Bilingual Acquisition --$tLaudatio: Hugo Baetens Beardsmore ? No Hyphen Please! --$tIndex 330 $aThe publication of Hugo Baetens Beardsmore?s book Bilingualism: Basic Principles by Multilingual Matters in 1982 coincided with an unprecedented upsurge of interest in bilingualism. A major reason for this was the acknowledgement that bilingualism is far more common than was previously thought, and perhaps even the norm. The number of bilinguals at the turn of the third millennium is probably greater than ever before and will continue to grow as a result of the combined forces of globalisation, automatisation, increased mobility and migration, and modernisation of foreign language teaching. The contributions in this book prove that, given the right conditions, bilingualism can confer distinct benefits like intellectual, psychological, social, cultural and economic improvement on the individual. The papers in this volume have been written by leading scholars in the field of bilingualism and deal with individual bilingualism, societal and educational phenomena, addressing issues such as bilingual usage, acquisition, teaching, and language planning and policy. The volume?s major asset lies in its diversity, not only in depth of investigation and in topical variety but also in the range of languages and geographical regions covered. Another important feature of the volume is its multidisciplinary perspective. Among the contributors are linguists, sociologists, psychologists and sociolinguists. 410 0$aMultilingual Matters S. 606 $aBilingualism 606 $aLanguage and languages 615 0$aBilingualism. 615 0$aLanguage and languages. 676 $a404/.2 701 $aDewaele$b Jean-Marc$f1962-$0769619 701 $aHousen$b Alex$f1964-$01801823 701 $aLi$b Wei$f1961 August 11-$01666121 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910956380203321 996 $aBilingualism$94475855 997 $aUNINA LEADER 03063nam 22006495 450 001 9910483773203321 005 20251225175053.0 010 $a3-030-68821-6 024 7 $a10.1007/978-3-030-68821-9 035 $a(CKB)4100000011774006 035 $a(MiAaPQ)EBC6484591 035 $a(PPN)253858631 035 $a(BIP)79253584 035 $a(BIP)78761269 035 $a(DE-He213)978-3-030-68821-9 035 $a(EXLCZ)994100000011774006 100 $a20210220d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPattern Recognition. ICPR International Workshops and Challenges $eVirtual Event, January 10?15, 2021, Proceedings, Part V /$fedited by Alberto Del Bimbo, Rita Cucchiara, Stan Sclaroff, Giovanni Maria Farinella, Tao Mei, Marco Bertini, Hugo Jair Escalante, Roberto Vezzani 205 $a1st ed. 2021. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2021. 215 $a1 online resource (706 pages) 225 1 $aImage Processing, Computer Vision, Pattern Recognition, and Graphics,$x3004-9954 ;$v12665 311 08$a3-030-68820-8 330 $aThis 8-volumes set constitutes the refereed of the 25th International Conference on Pattern Recognition Workshops, ICPR 2020, held virtually in Milan, Italy and rescheduled to January 10 - 11, 2021 due to Covid-19 pandemic. The 416 full papers presented in these 8 volumes were carefully reviewed and selected from about 700 submissions. The 46 workshops cover a wide range of areas including machine learning, pattern analysis, healthcare, human behavior, environment, surveillance, forensics and biometrics, robotics and egovision, cultural heritage and document analysis, retrieval, and women at ICPR2020. 410 0$aImage Processing, Computer Vision, Pattern Recognition, and Graphics,$x3004-9954 ;$v12665 606 $aImage processing$xDigital techniques 606 $aComputer vision 606 $aApplication software 606 $aArtificial intelligence 606 $aEducation$xData processing 606 $aComputer Imaging, Vision, Pattern Recognition and Graphics 606 $aComputer and Information Systems Applications 606 $aArtificial Intelligence 606 $aComputers and Education 615 0$aImage processing$xDigital techniques. 615 0$aComputer vision. 615 0$aApplication software. 615 0$aArtificial intelligence. 615 0$aEducation$xData processing. 615 14$aComputer Imaging, Vision, Pattern Recognition and Graphics. 615 24$aComputer and Information Systems Applications. 615 24$aArtificial Intelligence. 615 24$aComputers and Education. 676 $a006.4 702 $aDel Bimbo$b Alberto 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910483773203321 996 $aPattern Recognition. ICPR International Workshops and Challenges$92808746 997 $aUNINA LEADER 01361nas 2200373-a 450 001 9911049128303321 005 20240413024747.0 035 $a(CKB)110985646089649 035 $a(CONSER)---75642403- 035 $a(DE-599)ZDB3231960-5 035 $a(EXLCZ)99110985646089649 100 $a20751113b19741998 --- a 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBulletin of the New Zealand National Society for Earthquake Engineering 210 $a[Wellington] $cThe Society$d[1974-1998] 215 $a1 online resource 311 08$aPrint version: Bulletin of the New Zealand National Society for Earthquake Engineering. (DLC) 75642403 (OCoLC)2240743 0110-0718 531 $aBULL NZ NATL SOC EARTHQUAKE ENG 531 0 $aBull. N.Z. Natl. Soc. Earthq. 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