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010   $a3-540-29837-1
024 7 $a10.1007/3-540-29837-1
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035   $a(DE-He213)978-3-540-29837-3
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100   $a20110404d2002      u|             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aDrug Discovery and Evaluation: Pharmacological Assays$b[electronic resource] /$fedited by Hans G. Vogel
205   $a2nd ed. 2002.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2002.
215   $a1 online resource (1643 p.)
300   $aDescription based upon print version of record.
311   $a3-540-33360-6 
311   $a3-540-42396-6 
320   $aIncludes bibliographical references and index.
327   $a""Preface to the first edition""; ""Contributors""; ""Contents""; ""Introduction Strategies in drug discovery and evaluation""; ""Chapter A Cardiovascular activity""; ""Chapter B Activity on blood constituents""; ""Chapter C Activity on urinary tract""; ""Chapter E Psychotropic and neurotropic activity""; ""Chapter F Drug effects on learning and memory""; ""Chapter G Effects on peripheral nerve function""; ""Chapter J Activity on the gastrointestinal tract""; ""Chapter K Antidiabetic activity""; ""Chapter M Anti- atherosclerotic activity""; ""Chapter N Endocrinology""
327   $a""Chapter Q Guidelines for the care and use of laboratory animals""""Index""
330   $aNow expanded and updated to include molecular biology and genetic engineering techniques! The 2nd edition of this successful reference book contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic respiratory, renal and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. The enclosed and fully searchable CD-ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.
606   $aPharmacology
606   $aPharmacy
606   $aBiochemistry
606   $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007
606   $aPharmacy$3https://scigraph.springernature.com/ontologies/product-market-codes/F00008
606   $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005
615  0$aPharmacology.
615  0$aPharmacy.
615  0$aBiochemistry.
615 14$aPharmacology/Toxicology.
615 24$aPharmacy.
615 24$aBiochemistry, general.
676   $a615.10724
702   $aVogel$b Hans G$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910483681203321
996   $aDrug discovery and evaluation$9512478
997   $aUNINA