LEADER 02933nam 2200481 450 001 9910483500603321 005 20210117184905.0 010 $a1-4939-0694-1 024 7 $a10.1007/978-1-4939-0694-9 035 $a(CKB)3710000001127489 035 $a(DE-He213)978-1-4939-0694-9 035 $a(MiAaPQ)EBC6311295 035 $a(MiAaPQ)EBC5576242 035 $a(Au-PeEL)EBL5576242 035 $a(OCoLC)980301474 035 $a(PPN)199764492 035 $a(EXLCZ)993710000001127489 100 $a20201227d2017 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aHandbook of antimicrobial resistance /$fMatthias Gotte, editor-in-chief ; Albert Berghuis [and three others] (editors) 205 $a1st ed. 2017. 210 1$aNew York, New York :$cSpringer,$d[2017] 210 4$d©2017 215 $a1 online resource (73 illus., 42 illus. in color. eReference.) 311 $a1-4939-0693-3 327 $aBacteria -- Origins of antibiotic resistance (Resistome) -- Dissemination of antibiotic resistance -- Mechanisms of antibiotic resistance.-Strategies for combating antibiotic resistance.- Multiple-drug-resistant bacteria.- Resistant Tuberculosis -- MRSA.- Fungi -- Microevolution of drug resistance.- Environmental induction of azole resistance in medical molds -- Echinocandin resistance in medically relevant fungi -- Role of drug efflux in azole resistance.- Parasites.- Drug-resistant Leishmania -- Drug resistance in Helminth infections.- Drug resistance in Malaria -- Drug resistance in schistosome infections.- Drug resistance in trypanosome infections.- HIV.- Resistance to RT inhibitors.- Resistance to Integrase Inhibitors.- Resistance to Entry inhibitors.- Resistance Testing.- Virology -- Resistance to viral protease inhibitors: The substrate envelope.- Resistance to new Direct-Acting-Antivirals against HCV -- HBV Resistance.- Resistance to antiherpetic drugs -- Influenza Resistance. 330 $aThis is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution. 606 $aDrug resistance in microorganisms$vHandbooks, manuals, etc 615 0$aDrug resistance in microorganisms 676 $a616.90 702 $aBerghuis$b Albert 702 $aGo?tte$b Matthias 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910483500603321 996 $aHandbook of Antimicrobial Resistance$92079008 997 $aUNINA