LEADER 04624nam 22006735 450 001 9910483446203321 005 20251226203804.0 024 7 $a10.1007/11567752 035 $a(CKB)1000000000213308 035 $a(SSID)ssj0000320462 035 $a(PQKBManifestationID)11238883 035 $a(PQKBTitleCode)TC0000320462 035 $a(PQKBWorkID)10257807 035 $a(PQKB)10581384 035 $a(DE-He213)978-3-540-31661-9 035 $a(MiAaPQ)EBC3068327 035 $a(PPN)123098165 035 $a(BIP)13205893 035 $a(EXLCZ)991000000000213308 100 $a20100315d2005 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aTransactions on Computational Systems Biology II /$fedited by Alexander Zelikovsky 205 $a1st ed. 2005. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2005. 215 $a1 online resource (VIII, 156 p.) 225 1 $aTransactions on Computational Systems Biology ;$v3680 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$aPrinted edition: 9783540294016 320 $aIncludes bibliographical references and index. 327 $aWhat Makes the Arc-Preserving Subsequence Problem Hard? -- Profiling and Searching for RNA Pseudoknot Structures in Genomes -- A Class of New Kernels Based on High-Scored Pairs of k-Peptides for SVMs and Its Application for Prediction of Protein Subcellular Localization -- A Protein Structural Alphabet and Its Substitution Matrix CLESUM -- KXtractor: An Effective Biomedical Information Extraction Technique Based on Mixture Hidden Markov Models -- Phylogenetic Networks: Properties and Relationship to Trees and Clusters -- Minimum Parent-Offspring Recombination Haplotype Inference in Pedigrees -- Calculating Genomic Distances in Parallel Using OpenMP -- Improved Tag Set Design and Multiplexing Algorithms for Universal Arrays -- Virtual Gene: Using Correlations Between Genes to Select Informative Genes on Microarray Datasets. 330 $aIt gives me great pleasure to present the Special Issue of LNCS Transactions on Computational Systems Biology devoted to considerably extended versions of selected papers presented at the International Workshop on Bioinformatics Research and Applications (IWBRA 2005). The IWBRA workshop was a part of the International Conference on Computational Science (ICCS 2005) which took place in Emory University, Atlanta, Georgia, USA, May 22-24, 2005. See http://www.cs.gsu.edu/pan/ iwbra.htm for more details. The 10 papers selected for the special issue cover a wide range of bioinformatics research. The first papers are devoted to problems in RNA structure prediction: Blin et al. contribute to the arc-preserving subsequence problem and Liu et al. develop an efficient search of pseudoknots. The coding schemes and structural alphabets for protein structure prediction are discussed in the contributions of Lei and Dai, and Zheng and Liu, respectively. Song et al. propose a novel technique for efficient extraction of biomedical information. Nakhleh and Wang discuss introducing hybrid speciation and horizontal gene transfer in phylogenetic networks. Practical algorithms minimizing recombinations in pedigree phasing are proposed by Zhang et al. Kolliet al. propose a new parallel implementation in OpenMP for finding the edit distance between two signed gene permutations. The issue is concluded with two papers devoted to bioinformatics problems that arise in DNA microarrays: improved tag set design for universal tag arrays is suggested by Mandoiu et al. and a new method of gene selection is discussed by Xu and Zhang. 410 0$aTransactions on Computational Systems Biology ;$v3680 606 $aComputer science 606 $aBioinformatics 606 $aDatabase management 606 $aTheory of Computation 606 $aBioinformatics 606 $aDatabase Management 615 0$aComputer science. 615 0$aBioinformatics. 615 0$aDatabase management. 615 14$aTheory of Computation. 615 24$aBioinformatics. 615 24$aDatabase Management. 676 $a572.80285 701 $aPriami$b Corrado$01236801 701 $aZelikovsky$b Alexander$0919949 712 12$aInternational Workshop on Bioinformatics Research and Applications$f(2005 :$eAtlanta, Ga.) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910483446203321 996 $aTransactions on computational systems biology II$94184312 997 $aUNINA