LEADER 03263oam 2200517 450 001 9910483314303321 005 20210416123857.0 010 $a3-030-54391-9 024 7 $a10.1007/978-3-030-54391-4 035 $a(CKB)4100000011513458 035 $a(DE-He213)978-3-030-54391-4 035 $a(MiAaPQ)EBC6381389 035 $a(PPN)269151346 035 $a(EXLCZ)994100000011513458 100 $a20210416d2021 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 04$aThe spectrum of neuroendocrine neoplasia $ea practical approach to diagnosis, classification and therapy /$fedited by Sylvia L. Asa, Stefano La Rosa, Ozgur 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$d©2021 215 $a1 online resource (XI, 478 p.) 300 $aIncludes index. 311 $a3-030-54390-0 327 $aHistorical Background and Terminologies -- Clinical, Radiological and Biochemical Diagnosis of NENs -- Pituitary NENs -- NENs of the upper respiratory tract -- Thyroid NENs -- Parathyroid NENs -- Thoracic NENs (Lung/thymus) -- NENs of the tubular gut -- Pancreatic NENs -- Paragangliomas and tumors of the Adrenal Medulla -- Breast NENs -- Genitourinary NENs -- Skin NENs -- Metastatic NENs of unknown primary -- Cytology of NENs: Bongiovanni, Schmitt (Bern) -- Inherited NEN syndromes -- Management of the NEN patient. 330 $aNeuroendocrine neoplasms comprise a large family of proliferative lesions that involve almost every part of the body. Our understanding of their cells of origin as well as the pathology, pathophysiology and genetics of these neoplasms has made tremendous advances in the last few decades. While they are often discussed as separate entities in textbooks of gastroenteropancreatic pathology and pulmonary pathology, their scope is much broader. The book conveys the similarities and differences of these fascinating tumors that may be found from the hypothalamus and pituitary to the rectum, and in soft tissue as well as in many organs. Written by experts in the field, the authors emphasize their structural, functional, predictive and prognostic features and attempt to provide the clinical context that allows improved diagnosis and therapy while building on the genetics that clarifies patterns of inheritance and predisposition to tumor development through precursor lesions. The Spectrum of Neuroendocrine Neoplasia provides a broad overview of neuroendocrine neoplasms using a practical approach to diagnosis, histological classification and therapy, and presents the most important and significant developments of the technologies used to diagnose, classify and treat them. 606 $aEndocrinology 606 $aOncology 606 $aPathology 615 0$aEndocrinology. 615 0$aOncology. 615 0$aPathology. 676 $a016.6151 702 $aLa Rosa$b Stefano 702 $aAsa$b Sylvia L. 702 $aMete$b Ozgur 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bUtOrBLW 906 $aBOOK 912 $a9910483314303321 996 $aThe spectrum of neuroendocrine neoplasia$92571676 997 $aUNINA