LEADER 05417nam 22006855 450 001 9910482868703321 005 20240209132410.0 010 $a3-030-65768-X 024 7 $a10.1007/978-3-030-65768-0 035 $a(CKB)5590000000474039 035 $a(MiAaPQ)EBC6628607 035 $a(Au-PeEL)EBL6628607 035 $a(OCoLC)1252918887 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/70785 035 $a(DE-He213)978-3-030-65768-0 035 $a(PPN)255881894 035 $a(EXLCZ)995590000000474039 100 $a20210520d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Heterogeneity of Cancer Metabolism /$fedited by Anne Le 205 $a2nd ed. 2021. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2021. 215 $a1 online resource (281 pages) 225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1311 311 $a3-030-65767-1 327 $aPart I. Basic Metabolism of Cancer Cells -- Glucose Metabolism in Cancer the Warburg effect and Beyond -- Glutamine Metabolism in Cancer -- The Heterogeneity of Lipid Metabolism in Cancer -- Part II. Heterogeneity of Cancer Metabolism -- The Multifaceted Glioblastoma: from Genomic Alterations to Metabolic Adaptions -- The Intricate Metabolism of Pancreatic Cancers -- The heterogeneity of breast cancer metabolism for therapy -- Non-Hodgkin Lymphoma Metabolism -- The Heterogeneity Metabolism of Renal Cell Carcinomas -- The Heterogeneity Metabolism of Liver Cancer -- Different Tumor Microenvironments Lead to Different Metabolic Phenotypes -- The Intratumoral Heterogeneity of Cancer Metabolism -- Cancer Stem Cells Metabolism -- Metabolism of Immune cells in the Tumor Microenvironment -- Part III. Relationship between Cancer Cells and Cancer-Associated Fibroblasts -- Metabolic Relationship between Cancer-Associated Fibroblasts and Cancer Cells -- Targeting Metabolic Cross Talk between Cancer Cells and Cancer-Associated Fibroblasts -- Part IV. The metabolic interplay between cancer and other diseases -- Diabetes and Cancer: the Epidemiological and Metabolic Associations -- Bridging the Metabolic Parallels between Neurological Diseases and Cancer -- Metabolic Intersection of Cancer and Cardiovascular Diseases: Opportunities for Cancer Therapy -- Index. 330 $aThis open access volume will introduce recent discoveries in the field of cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, etc. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students. . 410 0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1311 606 $aCancer 606 $aMetabolism 606 $aCancer$xTreatment 606 $aCancer Metabolism 606 $aCancer Therapy 606 $aCancer Biology 606 $aCāncer$2thub 606 $aTrastorns del metabolisme$2thub 608 $aLlibres electrōnics$2thub 615 0$aCancer. 615 0$aMetabolism. 615 0$aCancer$xTreatment. 615 14$aCancer Metabolism. 615 24$aCancer Therapy. 615 24$aCancer Biology. 615 7$aCāncer 615 7$aTrastorns del metabolisme 676 $a571.978 676 $a572.4 700 $aLe$b Anne$0978317 702 $aLe$b Anne$4oth 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910482868703321 996 $aThe Heterogeneity of Cancer Metabolism$92229545 997 $aUNINA