LEADER 01558nam 2200445 450 001 9910480147103321 010 $a1-4704-4379-1 035 $a(CKB)4340000000264743 035 $a(MiAaPQ)EBC5347070 035 $a(PPN)225925001 035 $a(EXLCZ)994340000000264743 100 $a20180512d2018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aType II blow up manifolds for the energy supercritical semilinear wave equation /$fCharles Collot 210 1$aProvidence, RI :$cAmerican Mathematical Society,$d[2018] 210 4$dİ2018 215 $a1 online resource (176 pages) 225 1 $aMemoirs of the American Mathematical Society,$x0065-9266 ;$vVolume 252, Number 1205 311 $a1-4704-2813-X 320 $aIncludes bibliographical references and index. 410 0$aMemoirs of the American Mathematical Society ;$vVolume 252, Number 1205. 517 3 $aType two blow up manifolds for the energy supercritical semilinear wave equation 606 $aWave equation 606 $aManifolds (Mathematics) 608 $aElectronic books. 615 0$aWave equation. 615 0$aManifolds (Mathematics) 676 $a530.12/4 700 $aCollot$b Charles$f1990-$0871733 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910480147103321 996 $aType II blow up manifolds for the energy supercritical semilinear wave equation$91945820 997 $aUNINA LEADER 03969nam 22007815 450 001 9910743243003321 005 20251202170811.0 010 $a9789811660924 010 $a9811660921 010 $a9789811660917 010 $a9811660913 024 7 $a10.1007/978-981-16-6092-4 035 $a(MiAaPQ)EBC6887187 035 $a(Au-PeEL)EBL6887187 035 $a(CKB)21167330000041 035 $a(PPN)260831069 035 $a(BIP)83232379 035 $a(BIP)81250056 035 $a(DE-He213)978-981-16-6092-4 035 $a(EXLCZ)9921167330000041 100 $a20220211d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIntroduction to Toxicological Screening Methods and Good Laboratory Practice /$fby Saravana Babu Chidambaram, M. Mohamed Essa, M. Walid Qoronfleh 205 $a1st ed. 2022. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2022. 215 $a1 online resource (205 pages) 311 08$aPrint version: Chidambaram, Saravana Babu Introduction to Toxicological Screening Methods and Good Laboratory Practice Singapore : Springer Singapore Pte. Limited,c2022 9789811660917 311 08$a9811660913 320 $aIncludes bibliographical references. 327 $aChapter 1. Introduction to Toxicology -- Chapter 2. Laboratory Animal models -- Chapter 3. Toxicology Screening Methods -- Chapter 4. Toxicokinetics -- Chapter 5. Safety Pharmacology -- Chapter 6. Good Laboratory Practice. 330 $aThis book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ?Y?, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities. 606 $aToxicology 606 $aPharmacology 606 $aMedical sciences 606 $aDrug development 606 $aPharmacy 606 $aPharmaceutical chemistry 606 $aToxicology 606 $aPharmacology 606 $aPreclinical Research 606 $aPharmacy 606 $aPharmaceutics 615 0$aToxicology. 615 0$aPharmacology. 615 0$aMedical sciences. 615 0$aDrug development. 615 0$aPharmacy. 615 0$aPharmaceutical chemistry. 615 14$aToxicology. 615 24$aPharmacology. 615 24$aPreclinical Research. 615 24$aPharmacy. 615 24$aPharmaceutics. 676 $a615.9 700 $aChidambaram$b Saravana Babu$01427033 702 $aEssa$b M. Mohamed 702 $aQoronfleh$b M. Walid 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910743243003321 996 $aIntroduction to toxicological screening methods and good laboratory practice$93559739 997 $aUNINA