LEADER 05346nam 22005895 450 001 9910478902803321 005 20200630133702.0 010 $a1-4757-9427-4 024 7 $a10.1007/978-1-4757-9427-4 035 $a(CKB)2660000000024863 035 $a(SSID)ssj0000922489 035 $a(PQKBManifestationID)11520692 035 $a(PQKBTitleCode)TC0000922489 035 $a(PQKBWorkID)10848445 035 $a(PQKB)10264394 035 $a(DE-He213)978-1-4757-9427-4 035 $a(MiAaPQ)EBC3087101 035 $a(EXLCZ)992660000000024863 100 $a20130509d1998 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aBiochemistry$b[electronic resource] /$fby J. Stenesh 205 $a1st ed. 1998. 210 1$aNew York, NY :$cSpringer US :$cImprint: Springer,$d1998. 215 $a1 online resource (XXVII, 568 p. 1405 illus., 1327 illus. in color.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-306-45732-6 311 $a1-4757-9429-0 320 $aIncludes bibliographical references and index. 327 $aI. Foundation of Biochemistry -- 1. Frameworks of Biochemistry -- II. Biomolecules -- 2. Amino Acids and Peptides -- 3. Proteins -- 4. Enzymes -- 5. Carbohydrates -- 6. Lipids and Membranes -- 7. Nucleic Acids -- III. Metabolism -- 8. Introduction to Metabolism -- 9. Bioenergetics -- 10. Carbohydrate Metabolism -- 11. The Citric Acid Cycle -- 12. Electron Transport and Oxidative Phosphorylation -- 13. Lipid Metabolism -- 14 Amino Acid and Nucleotide Metabolism -- 15. Photosynthesis -- IV. Transfer of Genetic Information -- 16. Introduction to Molecular Biology -- 17. Replication?The Synthesis of DNA -- 18. Transcription?The Synthesis of RNA -- 19. Translation?The Synthesis of Protein -- Appendix A. Acid?Base Calculations -- A.1. Ionic Strength -- A.2. pH -- A.3. Henderson?Hasselbalch Equation -- A.4. Buffers -- Appendix B. Principles of Organic Chemistry -- B.1. Functional Groups -- B.2. Polar Reactions -- B.3. Chirality -- B.4. Optical Isomerism -- B.5. Conformation and Configuration -- Appendix C. Tools of Biochemistry -- C.1. Spectrophotometry -- C.2. Chromatography -- C.2.1. Adsorption Chromatography -- C.2.2. Ion-Exchange Chromatography -- C.2.3. Partition Chromatography -- C.2.4. Gel-Filtration Chromatography -- C.3. Centrifugation -- C3.1. Analytical Ultracentrifugation -- C.3.2. Density Gradient Centrifugation -- C.4. Electrophoresis -- C.5. Radioactivity -- C.6. Recombinant DNA Technology -- C.6.1. Selection of Target DNA Fragment -- C.6.2. Production of Recombinant DNA -- C.6.3. Insertion of Recombinant DNA into Host Cells -- C.6.4. Selection of Cells Containing Cloned DNA -- C.6.5. Polymerase Chain Reaction -- Appendix D. Oxidation?Reduction Reactions -- D.1. Half-Reactions -- D.2. Direction of Redox Reactions -- D.2.1. Standard Conditions -- D.2.2. Actual Conditions -- Answers to Problems. 330 $aThis text is intended for an introductory course in bio­ metabolism concludes with photosynthesis. The last sec­ chemistry. While such a course draws students from vari­ tion of the book, Part IV, TRANSFER OF GENETIC INFOR­ ous curricula, all students are presumed to have had at MATION, also opens with an introductory chapter and then least general chemistry and one semester of organic chem­ explores the expression of genetic information. Replica­ istry. tion, transcription, and translation are covered in this or­ My main goal in writing this book was to provide stu­ der. To allow for varying student backgrounds and for pos­ sible needed refreshers, a number of topics are included as dents with a basic body of biochemical knowledge and a thorough exposition of fundamental biochemical con­ four appendixes. These cover acid-base calculations, principles of cepts, including full definitions of key terms. My aim has of organic chemistry, tools biochemistry, and been to present this material in a reasonably balanced oxidation-reduction reactions. form by neither deluging central topics with excessive de­ Each chapter includes a summary, a list of selected tail nor slighting secondary topics by extreme brevity. readings, and a comprehensive study section that consists Every author of an introductory text struggles with of three types of review questions and a large number of the problem of what to include in the coverage. My guide­ problems. 606 $aBiochemistry 606 $aEvolutionary biology 606 $aChemistry 606 $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005 606 $aEvolutionary Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L21001 606 $aChemistry/Food Science, general$3https://scigraph.springernature.com/ontologies/product-market-codes/C00004 615 0$aBiochemistry. 615 0$aEvolutionary biology. 615 0$aChemistry. 615 14$aBiochemistry, general. 615 24$aEvolutionary Biology. 615 24$aChemistry/Food Science, general. 676 $a572 700 $aStenesh$b J$4aut$4http://id.loc.gov/vocabulary/relators/aut$0531255 906 $aBOOK 912 $a9910478902803321 996 $aBiochemistry$92279995 997 $aUNINA