LEADER 03635nam  22007695  450 
001 9910473450103321
005 20230410202452.0
010   $a3-030-63277-6
024 7 $a10.1007/978-3-030-63277-9
035   $a(CKB)4100000011797531
035   $a(DE-He213)978-3-030-63277-9
035   $a(MiAaPQ)EBC6515583
035   $a(Au-PeEL)EBL6515583
035   $a(OCoLC)1249471205
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/64050
035   $a(PPN)254725457
035   $a(EXLCZ)994100000011797531
100   $a20210311d2021      u|             0
101 0 $aeng
135   $aurnn#008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$a70 Years of Levothyroxine$b[electronic resource] /$fedited by George J. Kahaly
205   $a1st ed. 2021.
210   $cSpringer Nature$d2021
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2021.
215   $a1 online resource (XVII, 129 p. 37 illus., 34 illus. in color.)
311   $a3-030-63276-8 
327   $aHistory Of Levothyroxine -- Pharmacokinetics Of Levothyroxine -- Pharmacodynamics Of Levothyroxine  -- Levothyroxine In Pregnancy -- Levothyroxine In Children -- Levothyroxine In The Elderly -- Levothyroxine And Heart -- Levothyroxine And Bone -- Levothyroxine And Cancer -- Potential Adverse Reactions Of Levothyroxine.
330   $aThis open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.
606   $aEndocrinology 
606   $aPharmacology
606   $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053
606   $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007
606   $aHormones tiroides$2thub
606   $aMedicaments$2thub
606   $aFarmacologia$2thub
606   $aMalalties de les glàndules endocrines$2thub
608   $aLlibres electrònics$2thub
610   $aEndocrinology
610   $aPharmacology/Toxicology
610   $aPharmacology
610   $aThyroid gland
610   $aHypothyroidism
610   $aTSH
610   $aThyroid disorders
610   $aMetabolism
610   $aOpen Access
615  0$aEndocrinology .
615  0$aPharmacology.
615 14$aEndocrinology.
615 24$aPharmacology/Toxicology.
615  7$aHormones tiroides
615  7$aMedicaments
615  7$aFarmacologia
615  7$aMalalties de les glàndules endocrines
676   $a616.4
700   $aKahaly$b George J$4edt$01234680
702   $aKahaly$b George J$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910473450103321
996   $a70 Years of Levothyroxine$93361625
997   $aUNINA