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100   $a20190129d2019      uy             0
101 0 $aeng
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181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aData monitoring committees in clinical trials $ea practical perspective /$fSusan S. Ellenberg, Thomas R. Fleming, David I. DeMets
205   $aSecond edition.
210  1$aHoboken, NJ :$cWiley,$d2019.
215   $a1 online resource (493 pages)
225 1 $aStatistics in practice
300   $aPreceded by Data monitoring in committees in clinical trials : a practical perspective / Susan S. Ellenberg, Thomas R. Fleming, David L. DeMets. 2002.
311   $a1-119-51265-4 
320   $aIncludes bibliographical references and index.
327   $aResponsibilities of the data monitoring committee and motivating illustrations -- Composition of a data monitoring committee -- Independence of the data monitoring committee : avoiding conflicts of interest -- Confidentiality issues relating to the data monitoring committee -- Data monitoring committee meetings -- Data monitoring committee interactions with other trial components or related groups -- Statistical, philosophical and ethical issues in data monitoring -- Determining when a data monitoring committee is needed -- Regulatory considerations for the operation of data monitoring committees -- Legal considerations for DMCs.
410  0$aStatistics in practice.
608   $aElectronic books.
676   $a610.72/4
700   $aEllenberg$b Susan Smith$0850872
702   $aFleming$b Thomas R.
702   $aDeMets$b David L.$f1944-
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910467635603321
996   $aData monitoring committees in clinical trials$91899789
997   $aUNINA