LEADER 05230nam 22007215 450 001 9910467065003321 005 20190326051319.0 010 $a3-11-047952-4 010 $a3-11-047985-0 024 7 $a10.1515/9783110479850 035 $a(CKB)4100000001040907 035 $a(MiAaPQ)EBC5144649 035 $a(DE-B1597)466815 035 $a(OCoLC)1004886209 035 $a(OCoLC)1024010985 035 $a(DE-B1597)9783110479850 035 $a(EXLCZ)994100000001040907 100 $a20190326d2017 fg 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aIron-Sulfur Clusters in Chemistry and Biology. $hVolume 2, $iBiochemistry, Biosynthesis and Human Diseases /$fTracey Rouault 205 $a2. Aufl. 210 1$aBerlin ;$aBoston : $cDe Gruyter, $d[2017] 210 4$d©2017 215 $a1 online resource (492 pages) $cillustrations 225 0 $aIron-Sulfur Clusters in Chemistry and Biology ;$vVolume 2 311 $a3-11-047939-7 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $tFrontmatter -- $tPreface -- $tTracey A. Rouault biography -- $tContents -- $tList of contributing authors -- $t1 A retrospective on the discovery of [Fe-S] cluster biosynthetic machineries in Azotobacter vinelandii / $rDos Santos, Patricia C. / Dean, Dennis R. -- $t2 The ISC system and the different facets of Fe-S biology in bacteria / $rAussel, Laurent / Chareyre, Sylvia / Duverger, Yohann / Ezraty, Benjamin / Huguenot, Allison / Mandin, Pierre / Py, Béatrice / Zamarreno, Jordi / Barras, Frédéric -- $t3 A stress-responsive Fe-S cluster biogenesis system in bacteria - the suf operon of Gammaproteobacteria / $rOutten, F. Wayne -- $t4 Sensing the cellular Fe-S cluster demand: a structural, functional, and phylogenetic overview of Escherichia coli IscR / $rMettert, Erin L. / Perna, Nicole T. / Kiley, Patricia J. -- $t5 Fe-S assembly in Gram-positive bacteria / $rDos Santos, Patricia C. -- $t6 Fe-S cluster assembly and regulation in yeast / $rPain, Debkumar / Dancis, Andrew -- $t7 The role of Fe-S clusters in regulation of yeast iron homeostasis / $rOutten, Caryn E. -- $t8 Biogenesis of Fe-S proteins in mammals / $rRouault, Tracey -- $t9 Delivery of iron-sulfur clusters to recipient proteins: the role of chaperone and cochaperone proteins / $rMaio, Nunziata / Rouault, Tracey A. -- $t10 Iron-sulfur proteins and human diseases / $rTong, Wing Hang -- $t11 Friedreich ataxia / $rKnight, Simon A. B. / Wilson, Robert B. -- $t12 Connecting the biosynthesis of the molybdenum cofactor, Fe-S clusters, and tRNA thiolation in humans / $rLeimkühler, Silke -- $t13 Iron-sulphur proteins and genome stability / $rGari, Kerstin -- $t14 Eukaryotic iron-sulfur protein biogenesis and its role in maintaining genomic integrity / $rLill, Roland / Uzarska, Marta A. / Wohlschlegel, James -- $t15 DNA signaling by iron-sulfur cluster proteins / $rBartels, Phillip L. / O'Brien, Elizabeth / Barton, Jacqueline K. -- $t16 Iron-sulfur cluster assembly in plants / $rYe, Hong -- $t17 Origin and evolution of Fe-S proteins and enzymes / $rBoyd, Eric S. / Schut, Gerrit J. / Shepard, Eric M. / Broderick, Joan B. / Adams, Michael W. W. / Peters, John W. -- $tIndex 330 $aThis volume on iron-sulfur proteins includes chapters that discuss how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of iron sulfur proteins. In addition to their vital importance in mitochondrial respiration, numerous iron sulfur proteins are important in maintenance of DNA integrity. Multiple rare human diseases with different clinical presentations are caused by mutations of genes in the iron sulfur cluster biogenesis pathway. Understanding iron sulfur proteins is important for understanding a rapidly expanding group of metabolic pathways important in all kingdoms of life, and for understanding processes ranging from nitrogen fixation to human disease. 606 $aIron-sulfur proteins 608 $aElectronic books. 615 0$aIron-sulfur proteins. 676 $a574.19245 701 $aAdams$b Michael W.W$01053477 701 $aBoyd$b Eric S$01053478 701 $aBroderick$b Joan B$01053479 701 $aDancis$b Andy$01053480 701 $aDean$b Dennis$01053481 701 $aDos Santos$b Patricia$01053482 701 $aGari$b Kerstin$01053483 701 $aKiley$b Patricia$01053484 701 $aLeimkühler$b Silke$01053485 701 $aLill$b Roland$01053486 701 $aMaio$b Nunziata$01053487 701 $aMettert$b Erin L$01053488 701 $aOutten$b Caryn$01053489 701 $aOutten$b Wayne$01053490 701 $aPeters$b John$01053491 701 $aShepard$b Eric M$01053492 701 $aTong$b Wing Hang$01053493 701 $aWohlschlegel$b James$01053494 701 $aYe$b Hong$01053495 702 $aRouault$b Tracey, 801 0$bDE-B1597 801 1$bDE-B1597 906 $aBOOK 912 $a9910467065003321 996 $aIron-Sulfur Clusters in Chemistry and Biology$92485401 997 $aUNINA