LEADER 04643nam 2200613Ia 450 001 9910465400103321 005 20200520144314.0 010 $a1-61761-914-0 035 $a(CKB)2560000000067903 035 $a(EBL)3017772 035 $a(SSID)ssj0000417830 035 $a(PQKBManifestationID)12110638 035 $a(PQKBTitleCode)TC0000417830 035 $a(PQKBWorkID)10380210 035 $a(PQKB)10866897 035 $a(MiAaPQ)EBC3017772 035 $a(Au-PeEL)EBL3017772 035 $a(CaPaEBR)ebr10654743 035 $a(OCoLC)923653658 035 $a(EXLCZ)992560000000067903 100 $a20090414d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aFlavonoids$b[electronic resource] $ebiosynthesis, biological effects and dietary sources /$fRaymond B. Keller, editor 210 $aNew York $cNova Science Publishers$dc2009 215 $a1 online resource (363 p.) 225 0$aNutrition and diet research progress series 300 $aDescription based upon print version of record. 311 $a1-60741-622-0 320 $aIncludes bibliographical references and index. 327 $a""FLAVONOIDS: BIOSYNTHESIS, BIOLOGICAL EFFECTS AND DIETARY SOURCES ""; ""FLAVONOIDS: BIOSYNTHESIS, BIOLOGICAL EFFECTS AND DIETARY SOURCES""; ""CONTENTS""; ""PREFACE ""; ""BIOAVAILABILITY AND METABOLISM OF DIETARY FLAVONOIDS a??? MUCH KNOWN a??? MUCH MORE TO DISCOVER ""; ""ABSTRACT""; ""INTRODUCTION ""; ""FLAVONOID ABSORPTION AND METABOLISM IN THE GASTROINTESTINAL TRACT ""; ""The Oral Cavity ""; ""The Stomach ""; ""The Small Intestine ""; ""The Colon and Microflora""; ""DISTRIBUTION OF FLAVONOID METABOLITES ROUND THE BODY ""; ""FLAVONOID BIOAVAILABILITY TO THE CENTRAL NERVOUS SYSTEM "" 327 $a""BIOLOGICAL ACTIVITY OF FLAVONOID METABOLITES """"Quercetin/Flavonols ""; ""Isoflavones ""; ""Catechins ""; ""Other Flavonoids""; ""CONCLUSION ""; ""REFERENCES ""; ""CYTOPROTECTIVE ACTIVITY OF FLAVONOIDS IN RELATION TO THEIR CHEMICAL STRUCTURES AND PHYSICOCHEMICAL PROPERTIES ""; ""ABSTRACT ""; ""INTRODUCTION""; ""CHEMICAL STRUCTURE OF FLAVONOIDS ""; ""PHYSICOCHEMICAL PROPERTIES OF FLAVONOIDS ""; ""The UV Absorption of Flavonoids ""; ""Physical Properties of Flavonoids ""; ""Bond Dissociation Energy (BDE)""; ""Lipophilicity (Log P) ""; ""HEALTH EFFECTS OF FLAVONOIDS "" 327 $a""CYTOPROTECTION ASSAY """"MATERIALS AND METHODS ""; ""Materials ""; ""Assessment of Cell Viability ""; ""Culture and Treatment of HT-29 Cells ""; ""Annexin V Staining and Flow Cytometric Analysis ""; ""Calculation of Results""; ""Cell Death Index (CDI)""; ""Quantum Chemical Calculations ""; ""Calculation of Heat of Formation ""; ""Calculation of Log P ""; ""RESULTS AND DISCUSSION""; ""Cytotoxic Effects of H2O2 ""; ""Cytotoxicity of Flavonoids ""; ""The Influence of Trolox on Cytotoxic Effects of H2O2 ""; ""Structural Related Cytoprotective Activity of Flavonoids "" 327 $a""Effects of Hydroxyl Groups in the B Ring """"Effect of the 3-OH Group, 2,3-Double Bond and 4-Keto Group ""; ""Effect of the Carbohydrate Moieties""; ""Cytoprotective Activities and Physicochemical Properties of Flavonoids ""; ""Correlation between O-H Bond Dissociation Enthalpy (BDE) and Cytoprotective Activity (EC50) of Flavonoids ""; ""Correlation between Partition Coefficient (Log P) and Cytoprotective Activity (EC50) of Flavonoids ""; ""Quantitative Structure-Activity Relationship (QSAR) Model ""; ""CONCLUSION""; ""ACKNOWLEDGMENTS ""; ""REFERENCES "" 327 $a"" OLIGOMERIC NATURE, COLLOIDAL STATE, RHEOLOGY, ANTIOXIDANT CAPACITY AND ANTIVIRAL ACTIVITY OF POLYFLAVONOIDS""""ABSTRACT""; ""INTRODUCTION""; ""THE OLIGOMERIC NATURE OF POLYFLAVONOIDS ""; "" Profisetinindin and Prorobinetinidin Type Polyflavonoids ""; ""Procyanidin and Prodelphinidin Type Polyflavonoids ""; ""Colloidal State of Polyflavonoid Extracts""; ""RHEOLOGY OF INDUSTRIAL POLYFLAVONOIDS ""; ""ANTI-OXYDANT CAPABILITY OF POLYFLAVONOIDS ""; ""ANTIVIRAL ACTIVITY OF POLYFLAVONOIDS ""; ""REFERENCES""; ""GRAPEFRUIT FLAVONOIDS: NARINGIN AND NARINGININ ""; ""ABSTRACT ""; ""INTRODUCTION "" 327 $a""REFERENCES "" 410 0$aNutrition and Diet Research Progress 606 $aFlavonoids 606 $aPlant pigments 608 $aElectronic books. 615 0$aFlavonoids. 615 0$aPlant pigments. 676 $a612/.0154 701 $aKeller$b Raymond B$0926944 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910465400103321 996 $aFlavonoids$92082489 997 $aUNINA