LEADER 03275nam 2200625 a 450 001 9910465104103321 005 20200520144314.0 010 $a1-282-88572-3 010 $a9786612885723 010 $a0-309-15905-9 035 $a(CKB)2560000000068395 035 $a(EBL)3564192 035 $a(SSID)ssj0000427987 035 $a(PQKBManifestationID)11291000 035 $a(PQKBTitleCode)TC0000427987 035 $a(PQKBWorkID)10413746 035 $a(PQKB)10456475 035 $a(MiAaPQ)EBC3564192 035 $a(Au-PeEL)EBL3564192 035 $a(CaPaEBR)ebr10425168 035 $a(CaONFJC)MIL288572 035 $a(OCoLC)681623253 035 $a(EXLCZ)992560000000068395 100 $a20101202d2010 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSequence-based classification of select agents$b[electronic resource] $ea brighter line /$fCommittee on Scientific Milestones for the Development of a Gene Sequence-Based Classification System for the Oversight of Select Agents, Board on Life Sciences, Division on Earth and Life Studies, National Research Council of the National Academies 210 $aWashington, D.C. $cNational Academies Press$d2010 215 $a1 online resource (236 p.) 300 $aDescription based upon print version of record. 311 $a0-309-15904-0 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Preface""; ""Acknowledgments""; ""Contents""; ""Summary""; ""1 The Select Agent Regulations""; ""2 Challenges of Predicting Pathogenicity from Sequence""; ""3 A Proposal for Consideration: Sequence-Based Classification of Select Agents""; ""4 Committee Findings and Conclusions""; ""References""; ""Appendix A: Statement of Task""; ""Appendix B: Committee Member and Staff Biographies""; ""Appendix C: HHS and USDA Select Agents and Toxins""; ""Appendix D: 2009 Workshop Agenda""; ""Appendix E: Applicability of the Select Agent Regulations to Issues of Synthetic Genomics"" 327 $a""Appendix F: Summary of Relevant Legislation, Regulation, and Guidance""""Appendix G: Influenza A and SARS-CoV""; ""Appendix H: Virus-Host Interactions""; ""Appendix I: Botulinum Neurotoxin, B. Anthracis and Variola Virus""; ""Appendix J: Pathogenicity Acquisition""; ""Appendix K: Interactions of Infectious Agents with the Host""; ""Appendix L: Near-Term Milestones for Consideration""; ""Appendix M: Executive Order: Optimizing the Security of Biological Select Agents and Toxins in the United States"" 606 $aPathogenic microorganisms 606 $aMicrobiological laboratories$zUnited States$xSafety measures 606 $aGenetic engineering 606 $aMolecular biology 608 $aElectronic books. 615 0$aPathogenic microorganisms. 615 0$aMicrobiological laboratories$xSafety measures. 615 0$aGenetic engineering. 615 0$aMolecular biology. 676 $a660.6 712 02$aNational Research Council (U.S.).$bBoard on Life Sciences. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910465104103321 996 $aSequence-based classification of select agents$92447244 997 $aUNINA