LEADER 05428nam 2200649 450 001 9910465054303321 005 20191016115245.0 010 $a1-908230-98-3 035 $a(CKB)3710000000083273 035 $a(EBL)1909042 035 $a(SSID)ssj0001154051 035 $a(PQKBManifestationID)11719222 035 $a(PQKBTitleCode)TC0001154051 035 $a(PQKBWorkID)11154191 035 $a(PQKB)10544179 035 $a(MiAaPQ)EBC1909042 035 $a(MiAaPQ)EBC5897856 035 $a(Au-PeEL)EBL5897856 035 $a(OCoLC)874146835 035 $a(EXLCZ)993710000000083273 100 $a20191016d2014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCampylobacter ecology and evolution /$fedited by Samuel K. Sheppard ; associate editor, Guillaume Me?ric 210 1$aNorfolk, England :$cCaister Academic Press,$d[2014] 210 4$dİ2014 215 $a1 online resource (377 p.) 300 $a"Medical microbiology and infectious diseases, Swansea University, Swansea UK." 311 $a1-908230-36-3 320 $aIncludes bibliographical references and index. 327 $aContents; Current books of interest; Contributors; Foreword; Preface; Part I: Mechanisms of Evolution; 1: A Candidate Hopeful Monster in the Genus Campylobacter; Introduction; Hybridization by horizontal gene transfer; 2: Learning About Recombination in Campylobacter; Introduction; Estimating recombination from population data; Estimating recombination from closely related isolates; Discussion; 3: Within-host Evolution of Campylobacter jejuni; Introduction; Phenotypic changes of Campylobacter jejuni after host passage; Genotypic changes of Campylobacter jejuni during host passage; Conclusions 327 $aFuture studies4: Concerted Evolution in Campylobacter jejuni and Campylobacter coli; Concerted evolution; Duplicated genes in Campylobacter; Unresolved questions; 5: Genome and Transcriptome Evolution in the Genus Campylobacter; Introduction; Characteristics of Campylobacter genome sequences; Transcriptome evolution in the genus Campylobacter; Conclusions; 6: Repetitive DNA: A Major Source of Genetic Diversity in Campylobacter Populations?; Introduction; Types, prevalence and mutability of SSRs in Campylobacter genomes; Variation in SSRs has functionally important phenotypic effects 327 $aCombinatorial consequences of multiple phase-variable genesInfluence of mutational, selective and population forces on the diversity of phase-variable genotypes; Modelling phase-variable genes and selection for mutational rates; Experimental issues connected with phase variation; Summary; Future perspectives; Part II: Adaptations to Host Colonization; 7: Campylobacter Strategies for Colonizing the Host Gastrointestinal Tract; Introduction; Carbon sources utilized by Campylobacter to support growth in vivo; Mucins and the mucous layer; Conclusions and future trends 327 $a8: The Intricate Relationship Between Campylobacter and MucusThe stucture and function of intestinal mucus; The ecology of C. jejuni in intestinal mucus; Mucus as a source of glycans; Campylobacter jejuni commensalism in chickens; Conclusions and future directions; 9: Campylobacter Association with the Human Host; Introduction; Adhesion, invasion and translocation; Bacterial factors influencing adhesion and invasion of C. jejuni; Do all campylobacters invade to the same extent?; Conclusion; 10: Siderophore-mediated Iron Acquisition for Campylobacter Infection; Introduction 327 $aIron sources in the intestine: an ecological viewEnterobactin-mediated iron acquisition; Salmochelin-mediated iron acquisition; Hydroxamate siderophore-mediated iron acquisition; Conclusion and future directions; 11: Genetic Mechanisms Involved in Campylobacter jejuni Survival Under Oxidative Stress Conditions; The C. jejuni survival conundrum; Oxidative stress overview; C. jejuni mechanisms for countering oxidative stress; Oxidative stress regulation in C. jejuni; Discussion and future perspectives; 12: Oxidative Stress Survival During Campylobacter Transmission and Infection 327 $aCampylobacter jejuni transmission and aerotolerance 330 $aMembers of the genus Campylobacter are commonly found in the gastrointestinal tract of mammals and birds, and can be commensal or pathogenic in nature. For example, Campylobacter jejuni can be a harmless commensal organism in poultry and other avian and animal hosts, but in humans, it is pathogenic and the most common cause of bacterial gastroenteritis worldwide. In recent years, the application of DNA sequencing and 'omics' technologies to large numbers of isolates has allowed Campylobacter research to advance rapidly, revealing fascinating new insights into the cellular biology and evolution 606 $aCampylobacter 606 $aCampylobacter$xEcology 606 $aCampylobacter$xEvolution 608 $aElectronic books. 615 0$aCampylobacter. 615 0$aCampylobacter$xEcology. 615 0$aCampylobacter$xEvolution. 676 $a616.0145 702 $aSheppard$b Samuel$c(Microbiologist), 702 $aMe?ric$b Guillaume 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910465054303321 996 $aCampylobacter ecology and evolution$91918473 997 $aUNINA