LEADER 05560nam 2200625 450 001 9910463910003321 005 20200520144314.0 010 $a92-4-069172-3 035 $a(CKB)2670000000524345 035 $a(EBL)1612008 035 $a(SSID)ssj0001399223 035 $a(PQKBManifestationID)11867877 035 $a(PQKBTitleCode)TC0001399223 035 $a(PQKBWorkID)11450623 035 $a(PQKB)10983939 035 $a(MiAaPQ)EBC1612008 035 $a(Au-PeEL)EBL1612008 035 $a(CaPaEBR)ebr10931291 035 $a(OCoLC)870245961 035 $a(EXLCZ)992670000000524345 100 $a20140920h20132013 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aControl and surveillance of human African trypanosomiasis $ereport of a WHO Expert Committee /$fWorld Health Organization 210 1$aGeneva, Switzerland :$cWorld Health Organization,$d[2013] 210 4$dİ2013 215 $a1 online resource (249 p.) 225 1 $aWHO technical report series,$x0512-3054 ;$v984 300 $a"This report contains the collective views of an international group of experts and does not necessarily represent the decision or the stated policy of the World Health Organization"--T.p. 311 $a92-4-120984-4 320 $aIncludes bibliographical references. 327 $aCover; Contents; Abbreviations and acronyms; WHO Expert Committee on control and surveillance of human African trypanosomiasis; 1. Introduction; 2. Epidemiology of human African trypanosomiasis; 2.1 Two diseases, two parasites, two epidemiological patterns; 2.2 Transmission cycle; 2.2.1 Gambiense human African trypanosomiasis; 2.2.2 Rhodesiense human African trypanosomiasis; 2.3 Reservoirs of infection; 2.3.1 Gambiense human African trypanosomiasis; 2.3.2 Rhodesiense human African trypanosomiasis; 2.4 Risk factors for infection; 2.4.1 Gambiense human African trypanosomiasis 327 $a2.4.2 Rhodesiense human African trypanosomiasis2.5 Trends in numbers of cases reported; 2.5.1 Gambiense human African trypanosomiasis; 2.5.2 Rhodesiense human African trypanosomiasis; 2.6 Geographical distribution and population at risk; 2.7 Global environmental change; 2.8 References; 3. The parasite; 3.1 Taxonomy of human infectious African trypanosomes; 3.2 Morphology and cell structure; 3.3 Life-cycle; 3.4 The Trypanosoma brucei genome; 3.5 Immune evasion; 3.6 Biochemistry and modes of drug action; 3.7 Drug resistance; 3.8 References; 4. The vector; 4.1 Classification 327 $a4.1.1 Subgenus Nemorhina4.1.2 Subgenus Glossina s. str.; 4.1.3 Subgenus Austenina; 4.2 Reproductive system; 4.3 Reproduction; 4.4 Lifespan and population dynamics; 4.5 Diet; 4.6 Geographical distribution of the main vector species; 4.6.1 Vector species of the Nemorhina subgenus; 4.6.2 Vector species of the Glossina s. str. subgenus; 4.6.3 Vector species of the Austenina subgenus; 4.7 Tsetse flies in their natural environment; 4.7.1 Main habitats; 4.7.2 Movements; 4.7.3 Looking for hosts; 4.7.4 Feeding preferences; 4.7.5 Activity cycles; 4.7.6 Dispersal; 4.7.7 Resting places 327 $a4.8 Population genetics and geometric morphometrics4.9 Genomics of tsetse flies; 4.10 Tsetse flies as cyclical vectors; 4.11 Vector control strategies; 4.11.1 Control; 4.11.2 Eradication; 4.11.3 Preliminary surveys; 4.12 Tsetse fly control methods; 4.12.1 Bush clearing; 4.12.2 Elimination of wild animal hosts; 4.12.3 Biological control of tsetse flies; 4.12.4 Autonomous control of tsetse flies; 4.12.5 Indigenous tsetse fly control practices; 4.12.6 Ground and aerial insecticide spraying; 4.12.7 Protecting zero grazing units by insecticide-impregnated netting; 4.12.8 Bait methods 327 $a4.12.9 Olfactory baits (attractants) for tsetse flies4.12.10 Live baits; 4.12.11 Sterile insect technique; 4.13 New developments and outlook; 4.14 References; 5. The disease; 5.1 Gambiense human African trypanosomiasis: clinical signs and symptoms; 5.1.1 Lymphadenopathy; 5.1.2 Fever; 5.1.3 Headache; 5.1.4 Pruritus; 5.1.5 Musculoskeletal pain, hepatomegaly and splenomegaly; 5.1.6 Cardiac involvement; 5.1.7 Gastrointestinal symptoms; 5.1.8 Oedema; 5.1.9 Sleep disorder; 5.1.10 Neuropsychiatric symptoms and signs; 5.1.11 Endocrine disorders 327 $a5.2 Rhodesiense human African trypanosomiasis: clinical signs and symptoms 330 $aThis report provides information about new diagnostic approaches new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease.Human African Tryponosomiasis (HAT) is a disease that afflicts populations 410 0$aTechnical report series (World Health Organization) ;$v984. 606 $aTrypanosomiasis$zAfrica 608 $aElectronic books. 615 0$aTrypanosomiasis 676 $a614.5 676 $a614.533 712 02$aWHO Expert Committee on Control and Surveillance of Human African Trypanosomiasis, 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910463910003321 996 $aControl and surveillance of human African trypanosomiasis$92236359 997 $aUNINA