LEADER 03346nam 2200637 450 001 9910463686403321 005 20200520144314.0 010 $a1-4511-2453-8 010 $a1-4698-7482-2 035 $a(CKB)3400000000000422 035 $a(EBL)2031972 035 $a(OCoLC)686682029 035 $a(SSID)ssj0000445972 035 $a(PQKBManifestationID)12158423 035 $a(PQKBTitleCode)TC0000445972 035 $a(PQKBWorkID)10491383 035 $a(PQKB)10211488 035 $a(MiAaPQ)EBC2031972 035 $a(Au-PeEL)EBL2031972 035 $a(CaPaEBR)ebr10824498 035 $a(EXLCZ)993400000000000422 100 $a20100607h20112011 uy| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCancer chemotherapy and biotherapy $eprinciples and practice /$fBruce A. Chabner, Dan L. Longo 205 $aFifth edition. 210 1$aPhiladelphia :$cWolters Kluwer Health/Lippincott Williams & Wilkins,$d[2011] 210 4$dİ2011 215 $a1 online resource (836 p.) 300 $aDescription based upon print version of record. 311 $a1-60547-431-2 320 $aIncludes bibliographical references and index. 327 $asection I. Basic principles of cancer treatment -- section II. Cytotoxic agents -- section III. Molecularly targeted therapies -- section IV. Immunologic agents -- section V. Hormonal therapy -- section VI. Supportive care -- section VII. Survivorship. 330 $a"Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. The previous edition was one of "Doody's Core Titles 2009." This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised"--Provided by publisher. 606 $aCancer$xChemotherapy 606 $aCancer$xImmunotherapy 606 $aAntineoplastic agents 606 $aBiological response modifiers 608 $aElectronic books. 615 0$aCancer$xChemotherapy. 615 0$aCancer$xImmunotherapy. 615 0$aAntineoplastic agents. 615 0$aBiological response modifiers. 676 $a616.99/4061 701 $aChabner$b Bruce$0872435 701 $aLongo$b Dan L$g(Dan Louis),$f1949-$0327601 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910463686403321 996 $aCancer chemotherapy and biotherapy$91947713 997 $aUNINA