LEADER 03557nam  2200613   450 
001 9910463440103321
005 20200520144314.0
010   $a0-19-938980-2
010   $a0-19-935499-5
035   $a(CKB)2670000000491139
035   $a(EBL)1578262
035   $a(SSID)ssj0001061445
035   $a(PQKBManifestationID)12489667
035   $a(PQKBTitleCode)TC0001061445
035   $a(PQKBWorkID)11111123
035   $a(PQKB)11746435
035   $a(StDuBDS)EDZ0000242424
035   $a(MiAaPQ)EBC1578262
035   $a(Au-PeEL)EBL1578262
035   $a(CaPaEBR)ebr10816694
035   $a(CaONFJC)MIL550692
035   $a(OCoLC)865334622
035   $a(EXLCZ)992670000000491139
100   $a20131219d2014      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 04$aThe OMICs $eapplications in neuroscience /$fedited by Giovanni Coppola
210  1$aOxford, England :$cOxford University Press,$d2014.
210  4$dİ2014
215   $a1 online resource (385 p.)
300   $aDescription based upon print version of record.
311   $a0-19-985545-5 
320   $aIncludes bibliographical references and index.
327   $aCover; THE OMICs; Copyright; CONTENTS; CONTRIBUTORS; PART ONE: DNA; 1. Medical DNA Sequencing in Neuroscience; 2 . Epigenomics: An Overview; 3. The Role of Epigenomics in Genetically Identical Individuals; PART TWO: RNA; 4. Transcriptomics; 5. Decoding Alternative mRNAs in the "Omics" Age; 6. Transcriptomics: From Differential Expression to Coexpression; 7. High-Throughput RNA Interference as a Tool for Discovery in Neuroscience; 8. The Genetics of Gene Expression: Multiple Layers and Multiple Players; PART THREE: PROTEIN; 9. Proteomics
327   $a10. Focused Plasma Proteomics for the Study of Brain Aging and NeurodegenerationPART FOUR: CELLS AND CONNECTIONS; 11. Cellomics: Characterization of Neural Subtypes by High-Throughput Methods and Transgenic Mouse Models; 12. Neuroscience and Metabolomics; 13. Brain Connectomics in Man and Mouse; 14. Optogenetics; 15. Characterizing the Gut Microbiome: Role in Brain-Gut Function; PART FIVE: THERAPEUTICS; 16. OMICs in Drug Discovery: From Small Molecule Leads to Clinical Candidates; 17. Pharmacogenomics; PART SIX: OMICsOME: INTEGRATION OF OMICs DATA
327   $a18. Multidimensional Databases of Model Organisms19. Network Biology and Molecular Medicine in the Postgenomic Era: The Systems Pathobiology of Network Medicine; Links to Helpful Resources; Index
330   $aThe OMICs: Applications in Neuroscience summarizes the state of the art in high-throughput approaches (collectively known as 'OMICs') in neurology and neuroscience, and is of interest to both neurologists tracking the progress of these methods towards clinical applications, and neuroscientists curious about the most recent advances in this ever-changing field. The explosion of high-throughput assays has introduced large datasets, computational servers, and bioinformatics approaches to neuroscience, and medicine in general. The book includes a rich survey of the most relevant OMICs applications
606   $aBrain$xPhysiology
606   $aGenomics
608   $aElectronic books.
615  0$aBrain$xPhysiology.
615  0$aGenomics.
676   $a612.8/2
701   $aCoppola$b Giovanni$038910
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910463440103321
996   $aThe OMICs$92168552
997   $aUNINA