LEADER 06664nam 22011053u 450 001 9910462793303321 005 20210117142203.0 010 $a1-299-13218-9 010 $a1-119-94105-9 010 $a1-119-94266-7 035 $a(CKB)2670000000315452 035 $a(EBL)1108507 035 $a(OCoLC)823718924 035 $a(SSID)ssj0000803943 035 $a(PQKBManifestationID)11430592 035 $a(PQKBTitleCode)TC0000803943 035 $a(PQKBWorkID)10813780 035 $a(PQKB)10358576 035 $a(MiAaPQ)EBC1108507 035 $a(MiAaPQ)EBC4956632 035 $a(Au-PeEL)EBL4956632 035 $a(CaONFJC)MIL444468 035 $a(OCoLC)1027169054 035 $a(EXLCZ)992670000000315452 100 $a20131230d2013|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aExtreme Tissue Engineering$b[electronic resource] $eConcepts and Strategies for Tissue Fabrication 205 $a1st ed. 210 $aHoboken $cWiley$d2013 215 $a1 online resource (270 p.) 300 $aDescription based upon print version of record. 311 $a0-470-97446-X 327 $aExtreme Tissue Engineering; Contents; Preface: Extreme Tissue Engineering-a User's Guide; Chapter 1 Which Tissue Engineering Tribe Are You From?; 1.1 Why do we need to engineer tissues at all?; 1.1.1 Will the real tissue engineering and regenerative medicine please stand up?; 1.1.2 Other people's definitions; 1.1.3 Defining our tissue engineering: fixing where we are on the scale-hierarchy; 1.2 Bio-integration as a fundamental component of engineering tissues; 1.2.1 Bio-scientists and physical scientists/engineers: understanding diversity in TERM 327 $a1.3 What are the `tribes' of tissue engineering?1.3.1 Special needs for special characteristics: why is networking essential for TERM?; 1.4 Surprises from tissue engineering (Veselius to Vacanti); 1.5 So, really, is there any difference between tissue engineering and regenerative medicine?; 1.5.1 Questions never really asked: repair versus regeneration?; 1.5.2 Understanding the full spectrum: tissue replacement, repair and regeneration; 1.6 Conclusions; 1.7 Summarizing definitions; Annex 1 Other people's definitions of tissue engineering 327 $aAnnex 2 Other people's definitions of regenerative medicineFurther reading; Chapter 2 Checking Out the Tissue Groupings and the Small Print; 2.1 Checking the small print: what did we agree to engineer?; 2.2 Identifying special tissue needs, problems and opportunities; 2.3 When is `aiming high' just `over the top'?; 2.4 Opportunities, risks and problems; 2.4.1 Experimental model tissues (as distinct from spare-parts and fully regenerated tissues); 2.4.2 The pressing need for 3D model tissues; 2.4.3 Tissue models can be useful spin-offs on the way to implants 327 $a2.5 Special needs for model tissues2.5.1 Cell selection: constancy versus correctness; 2.5.2 Support matrices-can synthetics fake it?; 2.5.3 Tissue dimensions: when size does matter!; 2.6 Opportunities and sub-divisions for engineering clinical implant tissues; 2.6.1 Making physiological implants: spare parts or complete replacement?; 2.6.2 Making pathological and aphysiological constructs: inventing new parts and new uses; 2.6.3 Learning to use the plethora of tissue requirements as an opportunity; 2.7 Overall summary; Further reading; Chapter 3 What Cells `Hear' When We Say `3D' 327 $a3.1 Sensing your environment in three dimensions: seeing the cues3.2 What is this 3D cell culture thing?; 3.3 Is 3D, for cells, more than a stack of 2Ds?; 3.4 On, in and between tissues: what is it like to be a cell?; 3.5 Different forms of cell-space: 2D, 3D, pseudo-3D and 4D cell culture; 3.5.1 What has `3D' ever done for me?; 3.5.2 Introducing extracellular matrix; 3.5.3 Diffusion and mass transport; 3.5.4 Oxygen mass transport and gradients in 3D engineered tissues: scaling Mount Doom; 3.6 Matrix-rich, cell-rich and pseudo-3D cell cultures 327 $a3.7 4D cultures-or cultures with a 4th dimension? 330 $a Highly Commended at the BMA Book Awards 2013 Extreme Tissue Engineering is an engaging introduction to Tissue Engineering and Regenerative Medicine (TERM), allowing the reader to understand, discern and place into context the mass of scientific, multi-disciplinary data currently flooding the field. It is designed to provide interdisciplinary, ground-up explanations in a digestible, entertaining way, creating a text which is relevant to all students of TERM regardless of their route into the field. Organised into three main sections: chapters 1 to 3 introduce and e 606 $aCell Culture Techniques 606 $aRegenerative Medicine - methods 606 $aTissue Engineering 606 $aTissue Scaffolds 606 $aCulture Techniques 606 $aInvestigative Techniques 606 $aMedicine 606 $aCulture Media 606 $aProstheses and Implants 606 $aEquipment and Supplies 606 $aHealth Occupations 606 $aClinical Laboratory Techniques 606 $aAnalytical, Diagnostic and Therapeutic Techniques and Equipment 606 $aDisciplines and Occupations 606 $aMethods 606 $aTissue Scaffolds 606 $aRegenerative Medicine 606 $aCell Culture Techniques 606 $aTissue Engineering 606 $aHealth & Biological Sciences$2HILCC 606 $aBiomedical Engineering$2HILCC 608 $aElectronic books. 615 4$aCell Culture Techniques. 615 4$aRegenerative Medicine - methods. 615 4$aTissue Engineering. 615 4$aTissue Scaffolds. 615 2$aCulture Techniques 615 2$aInvestigative Techniques 615 2$aMedicine 615 2$aCulture Media 615 2$aProstheses and Implants 615 2$aEquipment and Supplies 615 2$aHealth Occupations 615 2$aClinical Laboratory Techniques 615 2$aAnalytical, Diagnostic and Therapeutic Techniques and Equipment 615 2$aDisciplines and Occupations 615 2$aMethods 615 2$aTissue Scaffolds 615 2$aRegenerative Medicine 615 2$aCell Culture Techniques 615 2$aTissue Engineering 615 7$aHealth & Biological Sciences 615 7$aBiomedical Engineering 676 $a571.538 700 $aBrown$b Robert A$0148987 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910462793303321 996 $aExtreme Tissue Engineering$92450368 997 $aUNINA