LEADER 05731nam 22008893u 450 001 9910462660803321 005 20210108083325.0 035 $a(CKB)2670000000332619 035 $a(EBL)1667676 035 $a(SSID)ssj0000585051 035 $a(PQKBManifestationID)12264174 035 $a(PQKBTitleCode)TC0000585051 035 $a(PQKBWorkID)10593137 035 $a(PQKB)10642477 035 $a(MiAaPQ)EBC3329148 035 $a(EXLCZ)992670000000332619 100 $a20140414d2005|||| u|| | 101 0 $aeng 135 $aurcnu---unuuu 181 $ctxt 182 $cc 183 $acr 200 00$aCentral Nervous System Tumours of Childhood /$fedited by Eddy Estlin and Stephen Lowis 210 $aLondon $cMac Keith Press$d2005 215 $a1 online resource (372 p.) 225 1 $aClinics in developmental medicine,$x0069-4835 ;$vno.166 300 $aDescription based upon print version of record. 311 $a1-898683-38-7 327 $aCONTENTS; AUTHORS' APPOINTMENTS; 1. INTRODUCTION Eddy Estlin and Stephen Lowis; REFERENCES; 2. THE EPIDEMIOLOGY OF PAEDIATRIC CNS TUMOURS GA Amos Burke; Incidence of primary CNS tumours; Age and site distribution of primary brain and spinal tumours; Incidence of secondary and metastatic tumours; Epidemiological evidence for aetiological factors in primary childhood brain; Tumour syndromes; Summary; REFERENCES; 3. PAEDIATRIC CNS TUMOURS: NEUROIMAGING Shelley Renowden; Neuroimaging techniques; Tumour types; REFERENCES 327 $a4. PATHOLOGY AND MOLECULAR ONCOLOGY OF CHILDHOOD CNS TUMOURS Lucy B Rorke-Adams and Jaclyn A Biegel Neuroepithelial tumours; Non-neuroepithelial tumours; REFERENCES; 5. MOLECULAR APPROACHES TO THE UNDERSTANDING AND TREATMENT OF CHILDHOOD CNS TUMOURS Richard J Gilbertson; Advances in molecular biology techniques; Advances in pre-clinical disease models; Application of molecular biology to disease management; REFERENCES; Summary; 6. SURGICAL MANAGEMENT OF CNS TUMOURS IN THE PAEDIATRIC POPULATION Jerard Ross and John Thorne; General care; Perioperative management 327 $aSurgical roles in common tumoursAdjuncts to surgical management; The role of neuroendoscopy in tumour management; Epilepsy surgery; REFERENCES; 7. GENERAL PRINCIPLES OF RADIOTHERAPY Eddy Estlin and Stephen Lowis; Radiotherapy physics and biology; Techniques of radiotherapy administration; Side-effects of radiotherapy; Radiotherapy and the treatment of CNS tumours of childhood; Stereotactic radiosurgery in recurrent ependymoma; Conclusions and future directions; REFERENCES; 8. GENERAL PRINCIPLES OF CHEMOTHERAPY Eddy Estlin; Pharmacology and tumours of the CNS; Chemosensitivity and CNS tumours 327 $aClinical trials involving paediatric CNS tumoursRelationship between pharmacology, chemosensitivity and clinical effect; Summary and conclusions; REFERENCES; 9. MANAGEMENT OF COMPLICATIONS AT PRESENTATION FOR CHILDREN WITH CNS TUMOURS Stephen Lowis; Impaired consciousness, encephalopathy; Spinal cord compression; Electrolyte and endocrine disturbance; REFERENCES; 10. LOW-GRADE AND HIGH-GRADE ASTROCYTOMA Eddy Estlin and Stephen Lowis ; Low-grade glioma; High-grade astrocytoma; Conclusions; REFERENCES; 11. EPENDYMOMA Ute Bartels, Douglas J Hyder, Annie Huang and Eric Bouffet 327 $aHistopathological featuresMolecular biology and cytogenetic studies; Diagnostic features of intracranial ependymomas; Risk factors and prognostic considerations; Treatment; Recurrent ependymoma; Conclusions and further directions; REFERENCES; 12. BRAINSTEM TUMOURS Carolyn R Freeman and Jean-Pierre Farmer; Clinical presentation and imaging findings; Management; Prognosis; Controversies; REFERENCES; 13. PRIMITIVE NEUROECTODERMAL TUMOURS Stephen Lowis ; Pathology; Presentation; Assessment and staging; Prognostic factors; Therapy; Supratentorial PNET; Relapsed PNET; REFERENCES 327 $a14. INTRACRANIAL GERM CELL TUMOURS Susanne J Rogers and Frank H Saran 330 $aCovers all clinical aspects of central nervous system (CNS) tumours in children, including epidemiology and neuroimaging, the general principles of surgery and radiotherapy/chemotherapy as well as palliative care and quality of life. It also includes diagnosis and management, important areas of research which are important for clinical practice. 410 0$aClinics in developmental medicine ;$vno. 166. 606 $aTumors in children$xTumors 606 $aCentral nervous system 606 $aNervous System Neoplasms 606 $aAge Groups 606 $aNeoplasms by Site 606 $aPersons 606 $aNervous System Diseases 606 $aDiseases 606 $aNamed Groups 606 $aNeoplasms 606 $aCentral Nervous System Neoplasms 606 $aChild 606 $aMedicine$2HILCC 606 $aHealth & Biological Sciences$2HILCC 606 $aOncology$2HILCC 608 $aElectronic books. 615 0$aTumors in children$xTumors 615 0$aCentral nervous system 615 2$aNervous System Neoplasms 615 2$aAge Groups 615 2$aNeoplasms by Site 615 2$aPersons 615 2$aNervous System Diseases 615 2$aDiseases 615 2$aNamed Groups 615 2$aNeoplasms 615 2$aCentral Nervous System Neoplasms 615 2$aChild 615 7$aMedicine 615 7$aHealth & Biological Sciences 615 7$aOncology 676 $a618.92/994 702 $aEstlin$b Eddy 702 $aLowis$b Stephen 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910462660803321 996 $aCentral Nervous System Tumours of Childhood$92277651 997 $aUNINA