LEADER 05008nam 2200589 450 001 9910462572903321 005 20191011093702.0 010 $a1-908230-70-3 035 $a(CKB)2670000000420692 035 $a(EBL)1938085 035 $a(SSID)ssj0001058907 035 $a(PQKBManifestationID)12444022 035 $a(PQKBTitleCode)TC0001058907 035 $a(PQKBWorkID)11071766 035 $a(PQKB)11441955 035 $a(MiAaPQ)EBC1938085 035 $a(MiAaPQ)EBC5897809 035 $a(Au-PeEL)EBL5897809 035 $a(OCoLC)1128725764 035 $a(EXLCZ)992670000000420692 100 $a20191011d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBacterial toxins $egenetics, cellular biology and practical applications /$fEdited by Thomas Proft 210 1$aNorfolk, England :$cCaister Academic Press,$d[2013] 210 4$dİ2013 215 $a1 online resource (249 p.) 300 $aDescription based upon print version of record. 311 $a1-908230-28-2 320 $aIncludes bibliographical references and index. 327 $aTable of Contents; Chapter 1. Receptor-related Risk Factors for Verotoxin Pathogenesis; Verotoxins and their receptors; Receptor glycolipid; B subunit receptor-binding sites; VT signalling and internalization; Cholesterol masking of VT receptors; New model for VTB subunit pentamer binding plasma membrane Gb3; Cholesterol is key for VT-Gb3 retrograde transport; Regulation of Gb3 biosynthesis; Soluble GSL mimics; Conclusions; References; Chapter 2. The Helicobacter pylori CagA Protein: A Multifunctional BacterialToxin Delivered by Type IV Secretion; Introduction 327 $aThe cag pathogenicity island and its effector protein CagAThe Cag type IV secretion system as a toxin delivery system; CagA interaction partners and associated effects in host cells; Conclusions; Chapter 3. Pore-forming Toxins; Introduction; Introduction to Staphylococcus aureus ?-haemolysin; Nomenclature and early observations; Primary structure and regulation of toxin production; Three-dimensional structure and function; Role in disease pathogenesis; Summary and future perspectives - ?-toxin 327 $aIntroduction to the cholesterol-dependent cytolysins and membrane attack complex/perforin (MACPF) family proteinsGeneral features of the CDC primary structure; The CDC monomer crystal structure; Secretion of the CDCs; Cellular recognition; The CDC membrane anchoring system; The CDC allosteric pathway; Formation of the prepore oligomer; Formation of the pore complex; Ring versus arc oligomers; The CDCs and bacterial pathogenesis; The membrane attack complex/perforin (MACPF) proteins; Summary and futureperspectives - CDCs andMACPF proteins; References 327 $aChapter 4. Bacterial Enterotoxins as Immunomodulators and Vaccine AdjuvantsIntroduction; Cholera toxin: the prototype for ADP-ribosylating holotoxin adjuvants; LT: a more complex family of holotoxin adjuvants; Are ADP-ribosylating toxins in general good adjuvants?; Taking toxin adjuvant immunomodulation one step further; Concluding remarks; References; Chapter 5. Mobile Genetic Elements as Carriers for Bacterial Virulence Genes; Core and adaptive genome; The mobile bacterial genome; Mobile genetic elements and their role in virulence; Why MGEs encode exotoxins and other virulence factors? 327 $aRole of SOS inductionBacteriophage-encoding toxins and other virulence factors; Plasmids encoding toxins; Pathogenicity islands encoding toxins; Open questions; Web resources; References; Chapter 6. The Staphylococcal Superantigen-like Toxins; Introduction; The SSLs - an introduction; Genetics of the ssls; Molecular biology of the SSLs; SSL-related S. aureus immune evasion molecules; Mechanisms of immune evasion mediated by SSLs; Novel SSL-associated applications; Concluding remarks; References; Chapter 7. Botulinum Neurotoxins as Therapeutics; Introduction 327 $aMechanistic basis of BoNTs as therapeutics 330 $aToxins are virulence determinants that play an important role in microbial pathogenicity and/or evasion of the host immune response. This makes them ideal targets for the development of novel antimicrobial strategies. The potential applications of toxin research extend beyond simply combating microbial pathogens, and include use as novel anti-cancer drugs and other front-line medicines and as tools in neurobiology. In the field of cellular biology, toxins have become invaluable as tools for the manipulation and investigation of fundamental cellular and physiological processes. Research in this 606 $aBacterial toxins 608 $aElectronic books. 615 0$aBacterial toxins. 676 $a615.95293 702 $aProft$b Thomas 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910462572903321 996 $aBacterial toxins$92087346 997 $aUNINA LEADER 06779nam 22007575 450 001 9910495221903321 005 20251113184614.0 010 $a9783030710248 010 $a3030710246 024 7 $a10.1007/978-3-030-71024-8 035 $a(CKB)4100000012009579 035 $a(MiAaPQ)EBC6713995 035 $a(Au-PeEL)EBL6713995 035 $a(PPN)257355383 035 $a(DE-He213)978-3-030-71024-8 035 $a(EXLCZ)994100000012009579 100 $a20210826d2021 u| 0 101 0 $aeng 135 $aurcn#---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCrime, Mental Health and the Criminal Justice System in Africa $eA Psycho-Criminological Perspective /$fedited by Heng Choon (Oliver) Chan, Samuel Adjorlolo 205 $a1st ed. 2021. 210 1$aCham :$cSpringer International Publishing :$cImprint: Palgrave Macmillan,$d2021. 215 $a1 online resource (XXVIII, 411 pages) $c2 illustrations 311 08$aPrinted edition: 9783030710255 311 08$aPrinted edition: 9783030710262 311 08$aPrinted edition: 9783030710231 311 08$a3030710238 320 $aIncludes bibliographical references and index. 327 $aChapter 1: Introduction; Heng Choon (Oliver) Chan and Samuel Adjorlolo -- Part One: Theory and Research -- Chapter 2: Suicide, Suicidal Ideation, and Behavior among African Youths: A Psycho-social and Criminological Analysis; Richard A. Aborisade -- Chapter 3: Situating Suicide Attempt within the Notion of ?Social Suffering?: A New Public Mental Health Approach for Addressing a Psycho-criminological Problem in Ghana; Johnny Andoh Arthur -- Chapter 4: A Review of the Violent Nature of Criminal Victimization in South Africa; By: Johan van Graan -- Chapter 5: An Exploratory Study of Kidnapping as an Emerging Crime in Nigeria; By: Alaba Oludare -- Chapter 6: ?What is the Problem?? Citizen?s Experiences with the Police and Court in Ghana; Akosua A. Adu-Poku -- Chapter 7: ?Before I could, say Jack, I was in the Grip of the Police?: Experiences of Persons who Use Drugs and Their Encounters with the Police in Ghana; Feikoab Parimah, Charlotte O. Kwakye-Nuako, Maria Goretti Ane-Loglo, Mary Eyram Ashinyo, Timothy P. Debrah, & Samuel Hanu -- Chapter 8: Evaluating the Predictors of Stress among Police Officers in Nigeria: A Psychosocial Analysis; Oluwagbenga (Michael) Akinlabi -- Chapter 9: Job Satisfaction and Organizational Commitment among Prison Officers in Ghana: A Qualitative Exploration;Thomas D. Akoensi -- Part Two: Policy and Practice -- Chapter 10: An Overview of Serial Murder and its Investigation in South Africa; Gerard N. Labuschagne -- Chapter 11: The Constitutional Imperative, Common Law Position and Domestic Legislation in the Context of Mental Health Care in South Africa; Magdalen Swanepoel -- Chapter 12: Issues of Competence, Experience, and Psychological Awareness among Police Prosecutors Working on Cases of Child Sexual Abuse in Ghana; Charlotte O. Kwakye-Nuako -- Chapter 13: Mental Health of Prison Inmates within the Nigerian Criminal Justice System; Chiedu Eseadi -- Chapter 14: Crossing the Social Boundary: Black FemaleOffenders inside South African Institutions of Incarceration; NP Dastile -- Chapter 15: Conclusion; Samuel Adjorlolo and Heng Choon (Oliver) Chan. 330 $a?This book is a timely contribution towards infusing Afrocentric perspectives in African scholarship by indigenous scholars. I highly recommend it.? ? Emmanuel Onyeozili, Professor, Department of Criminal Justice, University of Maryland Eastern Shore, USA ?This edited volume has given a refreshing voice to psycho-criminological narratives in the continent. It is recommended for its breadth of coverage and the multi-disciplinary outlook of its authors.? ? Adegboyega Ogunwale, Consultant Psychiatrist, Neuropsychiatric Hospital, Aro, Nigeria ?This collection represents a significant step in the study of mental health, crime and criminal justice in Africa. The breadth of topics covered is impressive.? ? Justice Tankebe, Lecturer, Institute of Criminology, University of Cambridge, UK ?The editors did well to coordinate the efforts of the contributors. I highly recommend it for all who are interested in the nexus between crime, mental health, and criminal justice systems.? ? Francis D. Boateng, Assistant Professor, Department of Criminal Justice and Legal Studies, University of Mississippi, USA This book aims to serve as a comprehensive resource for a myriad of crime and mental health topics and issues in the African criminal justice system from a psycho-criminological perspective. Crime, Mental Health and the Criminal Justice System in Africa: A Psycho-Criminological Perspective is an ideal primary text for courses in criminology, criminal justice, and forensic psychology, as well as a source of reference for practitioners who deal with offenders or victims. Heng Choon (Oliver) Chan is Associate Professor of Criminology at City University of Hong Kong, Hong Kong, SAR. His research focuses on psycho-criminology of crimes and criminal behaviour, violent sexual offending, stalking behaviour, and Asian criminology. He is the author of several books and more than 90 peer-reviewed journal articles and book chapters. Samuel Adjorlolo is Senior Lecturer in the Department of Mental Health Nursing, University of Ghana, Ghana. His research interests centre on forensic mental health, child and adolescent mental health and maternal mental health. He has published over 30 articles in peer-reviewed journals. 606 $aCritical criminology 606 $aForensic psychology 606 $aCriminology 606 $aClinical psychology 606 $aPublic health 606 $aCritical Criminology 606 $aForensic Psychology 606 $aCrime Control and Security 606 $aCriminology in the Global South 606 $aClinical Psychology 606 $aPublic Health 615 0$aCritical criminology. 615 0$aForensic psychology. 615 0$aCriminology. 615 0$aClinical psychology. 615 0$aPublic health. 615 14$aCritical Criminology. 615 24$aForensic Psychology. 615 24$aCrime Control and Security. 615 24$aCriminology in the Global South. 615 24$aClinical Psychology. 615 24$aPublic Health. 676 $a364.968 676 $a364.30968 702 $aChan$b Heng Choon$f1981- 702 $aAdjorlolo$b Samuel 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910495221903321 996 $aCrime, Mental Health and the Criminal Justice System in Africa$91896782 997 $aUNINA