LEADER 05912nam 2200733Ia 450 001 9910462561703321 005 20211005013630.0 010 $a1-283-85336-1 010 $a1-4411-3450-6 010 $a1-4411-1300-2 035 $a(CKB)2670000000308459 035 $a(EBL)1080352 035 $a(OCoLC)820029337 035 $a(SSID)ssj0000832153 035 $a(PQKBManifestationID)11414354 035 $a(PQKBTitleCode)TC0000832153 035 $a(PQKBWorkID)10881960 035 $a(PQKB)10639326 035 $a(MiAaPQ)EBC1080352 035 $a(Au-PeEL)EBL1080352 035 $a(CaPaEBR)ebr10632566 035 $a(CaONFJC)MIL416586 035 $a(MiAaPQ)EBC6161826 035 $a(EXLCZ)992670000000308459 100 $a20121202d2013 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aContemporary computer-assisted language learning$b[electronic resource] /$fedited by Michael Thomas, Hayo Reinders and Mark Warschauer 210 $aLondon ;$aNew York $cBloomsbury Academic$d2013 215 $a1 online resource (417 p.) 225 0 $aContemporary studies in linguistics 300 $aDescription based upon print version of record. 311 $a1-4725-8607-7 311 $a1-4411-9362-6 320 $aIncludes bibliographical references and index. 327 $aCover; Half Title; Series; Title; Copyright; Dedication; Contents; Notes on contributors; Foreword; List of figures and tables; 1 Contemporary computer-assisted language learning: The role of digital media and incremental change; Summary; Introduction; Contemporary CALL: An exemplary case study; Aspects of contemporary CALL; Digital media and social CALL; Conclusion; PART ONE The CALL context; Section introduction; 2 Historical perspectives on CALL; Summary; Introduction; Origin of the term CALL; Early CALL: 1960's to 1970's; CALL and the microcomputer: The 1980's; Repositioning CALL: The 1990's 327 $aCALL and Web 2.0: The 2000's Conclusions; 3 Researching language learning in the age of social media; Summary; Introduction; Traditions; Environments, socio/affective dimensions and pedagogical processes; Conclusion, future directions; 4 Second language teacher education for CALL: An alignment of practice and theory; Summary; Introduction; The broad domain; Second language teacher education for CALL; The sociocultural in SLTE for CALL; Sociocultural theory; Activity theory; The Cambridge study; Conclusions; Acknowledgements; 5 Research on computers in language testing: Past, present and future 327 $aSummary Introduction; Overviews of CBLT; CBLT delivery; CBLT content; Example CBLT's; Conclusions; 6 Materials design in CALL: Social presence in online environments; Summary; Introduction; Social presence; The project: Set-up, participants, methodology and task design; Some findings; Conclusions; PART TWO CALL learning environments; Section introduction; 7 Telecollaboration and CALL; Summary; Introduction; The origins of telecollaboration; Models of telecollaborative exchange; Areas of telecollaborative research; Telecollaboration 2.0: Current approaches and research; Conclusions 327 $a8 Distance CALL online Summary; Introduction; What is distance CALL?; An integrated model of distance language learning; DCALL research seen through the integrated model; Current and future directions; 9 Language learning in virtual worlds: Research and practice; Summary; Introduction; A history and overview of VWs; Research on virtual worlds; Potential barriers to language learning in VWs; Primary education in virtual worlds: To Rez or not to Rez?; Conclusions; 10 Digital games and language learning; Summary; Introduction; Emerging initiatives on digital game-based learning 327 $aAdaption of commercial off the shelf (COTS) games Design of serious educational language learning games; Future development and research directions; 11 Mobile-assisted language learning; Summary; Introduction; Enabling aspects of mobile learning; Uses of mobile devices in language learning; Issues of concern with mobile learning; Emerging directions; Conclusions; 12 CALL in low-tech contexts; Summary; Introduction; Definition of low-technology contexts; Overview of how technology has been used in educational settings in the last few decades; CALL and low-tech environments 327 $aHow to use CALL in low-tech contexts 330 $aContemporary Computer-Assisted Language Learning (CALL) is a comprehensive, one-volume work written by leading international figures in the field focusing on a wide range of theoretical and methodological issues. It explains key terms and concepts, synthesizes the research literature and explores the implications of new and emerging technologies. The book includes chapters on key aspects for CALL such as design, teacher education, evaluation, teaching online and testing, as well as new trends such as social media. The volume takes a broad look at CALL and explores how a variety of theoretical 410 0$aContemporary Studies in Linguistics 606 $aLanguage and languages$xComputer-assisted instruction$xResearch 606 $aLanguage and languages$xResearch$xMethodology 606 $aLanguage acquisition$xResearch$xMethodology 608 $aElectronic books. 615 0$aLanguage and languages$xComputer-assisted instruction$xResearch. 615 0$aLanguage and languages$xResearch$xMethodology. 615 0$aLanguage acquisition$xResearch$xMethodology. 676 $a401.93 701 $aThomas$b Michael$f1969-$0864050 701 $aReinders$b Hayo$0864051 701 $aWarschauer$b Mark$0514234 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910462561703321 996 $aContemporary computer-assisted language learning$91928682 997 $aUNINA LEADER 05100nam 2200601Ia 450 001 9910145414903321 005 20170815114644.0 010 $a1-281-32244-X 010 $a9786611322441 010 $a0-470-75062-6 010 $a0-470-75167-3 035 $a(CKB)1000000000406326 035 $a(EBL)351004 035 $a(OCoLC)437214010 035 $a(SSID)ssj0000121987 035 $a(PQKBManifestationID)11147925 035 $a(PQKBTitleCode)TC0000121987 035 $a(PQKBWorkID)10109930 035 $a(PQKB)10343490 035 $a(MiAaPQ)EBC351004 035 $a(EXLCZ)991000000000406326 100 $a20010403d2001 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aChromatin and gene regulation$b[electronic resource] $emechanisms in epigenetics /$fBryan M. Turner 210 $aOxford ;$aMalden, MA $cBlackwell Science$d2001 215 $a1 online resource (298 p.) 300 $aDescription based upon print version of record. 311 $a0-86542-743-7 320 $aIncludes bibliographical references and index. 327 $aChromatin and Gene Regulation; Contents; Preface; Prologue; Chapter 1 Controlling Transcription: Shared Aims and Common Mechanisms; Introduction; Some general principles; Transcription in prokaryotes; Genetic switches in bacteria; Chapter 2 Transcription in Eukaryotes: The Problems of Complexity; Introduction; The emergence of eukaryotes; The transcription machinery in eukaryotes; General transcription factors, TAFs and the PolII pre-initiation complex; Transcription by PolI and PolIII; The elongation stage; Experimental considerations; Large genome problems: why are things so complicated? 327 $aChapter 3 The Nucleosome: Chromatin's Structural UnitIntroduction; Exploring how DNA is packaged in the nucleus; The structure of the nucleosome; Chapter 4 Histone Tails: Modifications and Epigenetic Information; Introduction; The histone tails; Histone modifications; Histone variants; Chapter 5 Higher-Order Chromatin Structures and Nuclear Organization; Introduction; The 30 nm fibre; DNA loops; The nuclear matrix and chromosome scaffolds; Scaffold/matrix associated regions (SARs and MARs); Chromosome bands and functional domains; Nuclear domains and structure in the interphase nucleus 327 $aChapter 6 Transcription in a Chromatin EnvironmentIntroduction; Genes are packaged into nucleosomes, even when they are being transcribed; Genetic experiments in yeast show the importance of histones for gene regulation; Changes in chromatin structure precede gene activation; Increased histone acetylation can precede or accompany the onset of transcription; DNaseI hypersensitive sites; Nucleosome positioning in vitro and in vivo; Chromatin domains; Chapter 7 How the Transcription Machinery Deals with Chromatin; Introduction; In vitro studies of transcription factor binding 327 $aA crowded nucleosome: Mouse Mammary Tumour Virus nucleosome BThe opportunities presented by DNA replication; Chromatin and the elongation stage of transcription; Chapter 8 Chromatin Remodelling Machines; Introduction; Nucleosome remodelling enzymes; Histone acetyltransferases (HATs); Histone deacetylases; The nuclear receptors; Chromatin and cancer; Chapter 9 Heterochromatin; Introduction; ? and ? heterochromatin in Drosophila; Facultative and constitutive heterochromatin; Heterochromatin DNA; Heterochromatin genes; Heterochromatin proteins; Position effect variegation 327 $aHeterochromatin and gene expression in mammalsChapter 10 Long-term Silencing of Gene Expression; Introduction; DNA methylation; Silencing at telomeres and mating type loci in yeast; Chapter 11 Cellular Memory and Imprinting; Introduction; Maintenance of transcriptional states; Imprinted genes; Chapter 12 Mechanisms of Dosage Compensation; Introduction; Methods of sex determination; Dosage compensation in mammals; Dosage compensation in Drosophila; Dosage compensation in C. elegans; Lessons from dosage compensation; Index 330 $aWritten in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by which cells respond to changes 606 $aChromatin 606 $aGenetic regulation 608 $aElectronic books. 615 0$aChromatin. 615 0$aGenetic regulation. 676 $a572.865 700 $aTurner$b Bryan M$0944682 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910145414903321 996 $aChromatin and gene regulation$92132538 997 $aUNINA