LEADER 05577nam 2200721Ia 450 001 9910461812503321 005 20200520144314.0 010 $a1-283-63593-3 010 $a981-4343-60-9 035 $a(CKB)2670000000272699 035 $a(EBL)1044404 035 $a(OCoLC)811816466 035 $a(SSID)ssj0000737490 035 $a(PQKBManifestationID)11469221 035 $a(PQKBTitleCode)TC0000737490 035 $a(PQKBWorkID)10783517 035 $a(PQKB)11350778 035 $a(MiAaPQ)EBC1044404 035 $a(WSP)00002793 035 $a(Au-PeEL)EBL1044404 035 $a(CaPaEBR)ebr10607803 035 $a(CaONFJC)MIL394839 035 $a(EXLCZ)992670000000272699 100 $a20101224d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aFrom inflammation to cancer$b[electronic resource] $eadvances in diagnosis and therapy for gastrointestinal and hepatological diseases /$feditors: Chi Hin Cho, Jun Yu 210 $aHackensack, NJ $cWorld Scientific$dc2012 215 $a1 online resource (378 p.) 300 $aDescription based upon print version of record. 311 $a981-4343-59-5 320 $aIncludes bibliographical references and index. 327 $aAbout the Editors; Foreword; List of Main Contributors; Contents; Section I Inflammation and Cancer; Chapter 1 General Introduction Chung Wah Wu and Jun Yu; Introduction; How inflammation and cancer are linked; Inflammation conditions that are linked to specific GI cancers; Bowel cancer; Barrett's esophagus and esophageal cancer; Viral infections and hepatocellular carcinomas; H. pylori infection and gastric cancer; Conclusion; References; Chapter 2 General Mechanisms of Inflammation Liwei Lu and Min Yang; Categories of inflammation; Inflammatory process; Initiation of inflammation 327 $aInflux of leukocytesEffector mechanisms; Termination of inflammation and tissue repair; Regulatory mechanisms of inflammation; Conclusion; References; Chapter 3 Genetic and Epigenetic Alterations in Inflammation-Related Cancers - General Mechanisms of Cancers Yasuyuki Okamoto and Yutaka Kondo; Introduction; Signaling pathways; NF- ?B; STAT3; RAS; TNF- ?; TAM; Genetic instability; Epigenetic alterations; DNA methylation; Histone modifications; Perspectives; References; Chapter 4 From Inflammation to Cancer: The Molecular Basis Hongchuan Jin; Inflammation and cancer: a brief overview of history 327 $aCurrent model of tumorigenesis: interplay between tumor stem cells and tumor-permissive microenvironmentTumor microenvironment; Non-tumor cells in tumor microenvironment; Cancer-associated fibroblast (CAFs); Immune cells; Bioactive factors in tumor microenvironment; Chemokines; Growth factors; MMPs and TIMPs (tissue inhibitors of metalloproteinases); Other cytokines; Intracellular signaling pathways; NF- ?B (nuclear factor ?light chain polypeptide gene enhancer in B cells) pathway; STAT3 (signal transducer and activator of transcription 3) pathway; Conclusions; References 327 $aSection II Models of Chronic Inflammation-Induced Cancers and Their TreatmentsChapter 5 Advances in the Treatment of Helicobacter pylori Infection and Gastric Cancer Guy D. Eslick; Introduction; Treatment of Helicobacter pylori infection; Guidelines for the treatment of H. pylori; Alternative therapies for H. pylori infection; Treatment of gastric cancer; Future directions in gastric cancer treatment; Prevention of gastric cancer by treating H. pylori infection; Conclusions; Acknowledgments; Dedication; References 327 $aChapter 6 Inflammatory Bowel Disease and Colorectal Cancer and Their Treatment Crispin Corte and Rupert WL LeongIntroduction; Epidemiology; Pathological characteristics; Risk of dysplasia; Colitis CRC surveillance guidelines; 1. Timing of commencement of surveillance; 2. Surveillance interval; 3. Techniques in surveillance for CRC; Dye-spray chromoendoscopy; Narrow band imaging; Fluorescence imaging; Confocal endomicroscopy; Management of dysplasia; 1. Endoscopic management of dysplasia; 1.1. Visualised lesions; 1.2. Flat lesions; 2. Chemoprophylaxis; 2.1. 5-Aminosalicylatic acid 327 $a2.2. Ursodeoxycholic acid 330 $aInflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs. The authors in this book comprehensively discuss the different biomarkers for early diagnosis, and current therapeutic treatments for these diseases. All of these would allow us to better understand the pathogenesis of both diseases. As such, this book provides compreh 606 $aGastroenteritis$xDiagnosis 606 $aHepatitis$xDiagnosis 606 $aGastrointestinal system$xCancer 606 $aLiver$xCancer 608 $aElectronic books. 615 0$aGastroenteritis$xDiagnosis. 615 0$aHepatitis$xDiagnosis. 615 0$aGastrointestinal system$xCancer. 615 0$aLiver$xCancer. 676 $a616.3 676 $a616.3/30654 676 $a616.3307 701 $aCho$b C.-H$g(Chi-Hin)$0859651 701 $aYu$b Jun$0845687 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910461812503321 996 $aFrom inflammation to cancer$91918456 997 $aUNINA