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101 0 $aeng
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181   $ctxt$2rdacontent
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200 10$aMultiscale modeling of cancer $ean integrated experimental and mathematical modeling approach /$fVittorio Cristini, John Lowengrub$b[electronic resource]
210  1$aCambridge :$cCambridge University Press,$d2010.
215   $a1 online resource (xix, 278 pages) $cdigital, PDF file(s)
300   $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
311   $a0-521-88442-X 
320   $aIncludes bibliographical references and index.
327   $aPart I. Theory: 1. Introduction; 2. Biological background; 3. Continuum tumor modeling: single phase; 4. Analysis and calibration of single-phase continuum tumor models; 5. Continuum tumor modeling: multiphase; 6. Discrete cell modeling; 7. Hybrid continuum -- discrete models; 8. Numerical schemes -- Part II. Applications: 9. Continuum tumor modeling: a multidisciplinary approach; 10. Agent-based cell modeling: application to breast cancer.
330   $aMathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
606   $aCancer$xResearch$xMathematical models
606   $aMultiscale modeling
615  0$aCancer$xResearch$xMathematical models.
615  0$aMultiscale modeling.
676   $a362.196/994
700   $aCristini$b Vittorio$f1970-$0748389
702   $aLowengrub$b John
801  0$bUkCbUP
801  1$bUkCbUP
906   $aBOOK
912   $a9910460059903321
996   $aMultiscale modeling of cancer$92456421
997   $aUNINA