LEADER 03830nam 22007452 450 001 9910459474803321 005 20151005020624.0 010 $a1-107-21621-4 010 $a0-511-85306-8 010 $a1-282-93079-6 010 $a9786612930799 010 $a0-511-97393-4 010 $a0-511-93188-3 010 $a0-511-93054-2 010 $a0-511-92803-3 010 $a0-511-93324-X 010 $a0-511-92550-6 035 $a(CKB)2670000000059135 035 $a(EBL)604995 035 $a(OCoLC)693761195 035 $a(SSID)ssj0000440058 035 $a(PQKBManifestationID)11288446 035 $a(PQKBTitleCode)TC0000440058 035 $a(PQKBWorkID)10471018 035 $a(PQKB)10429282 035 $a(UkCbUP)CR9780511973932 035 $a(MiAaPQ)EBC604995 035 $a(PPN)159135486 035 $a(Au-PeEL)EBL604995 035 $a(CaPaEBR)ebr10436320 035 $a(CaONFJC)MIL293079 035 $a(EXLCZ)992670000000059135 100 $a20101011d2011|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNerve and muscle /$fRichard D. Keynes, David J. Aidley, Christopher L.-H. Huang$b[electronic resource] 205 $aFourth edition. 210 1$aCambridge :$cCambridge University Press,$d2011. 215 $a1 online resource (x, 183 pages) $cdigital, PDF file(s) 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-73742-7 311 $a0-521-51955-1 320 $aIncludes bibliographical references and index. 327 $aCover; Half-title; Title; Copyright; Contents; Preface; 1 Structural organization of the nervous system; 2 Resting and action potentials; 3 The ionic permeability of the nerve membrane; 4 Membrane permeability changes during excitation; 5 Voltage-gated ion channels; 6 Cable theory and saltatory conduction; 7 Neuromuscular transmission; 8 Synaptic transmission in the nervous system; 9 The mechanism of contraction in skeletal muscle; 10 The activation of skeletal muscle; 11 Contractile function in skeletal muscle; 12 Cardiac muscle; 13 Smooth muscle; Further reading; References; Index 330 $aWritten with undergraduate students in mind, the new edition of this classic textbook provides a compact introduction to the physiology of nerve and muscle. It gives a straightforward account of the fundamentals accompanied by some of the experimental evidence upon which this understanding is based. It first explores the nature of nerve impulses, clarifying their mechanisms in terms of ion flow through molecular channels in cell membranes. There then follows an account of the synaptic transmission processes by which one excitable cell influences activity in another. Finally, the emphasis turns to the consequences of excitable activity in the activation of contraction in skeletal, cardiac and smooth muscle, highlighting the relationships between cellular structure and function. This fourth edition includes new material on the molecular nature of ion channels, the activation of skeletal muscle and the function of cardiac and smooth muscle, reflecting exciting new developments in these rapidly growing fields. 517 3 $aNerve & Muscle 606 $aMyoneural junction 606 $aNeuromuscular transmission 606 $aMuscle contraction 615 0$aMyoneural junction. 615 0$aNeuromuscular transmission. 615 0$aMuscle contraction. 676 $a573.7/528 700 $aKeynes$b R. D.$01034385 702 $aAidley$b David J. 702 $aHuang$b Christopher L.-H 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910459474803321 996 $aNerve and muscle$92453478 997 $aUNINA