LEADER 04216nam 22008053u 450 001 9910458629703321 005 20210106221845.0 010 $a1-280-75153-3 010 $a9786610751532 010 $a0-08-046908-6 035 $a(CKB)1000000000364151 035 $a(EBL)285783 035 $a(OCoLC)476037278 035 $a(SSID)ssj0000206027 035 $a(PQKBManifestationID)11189284 035 $a(PQKBTitleCode)TC0000206027 035 $a(PQKBWorkID)10212795 035 $a(PQKB)11223366 035 $a(MiAaPQ)EBC285783 035 $a(EXLCZ)991000000000364151 100 $a20140113d2006|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe Mouse in Biomedical Research$b[electronic resource] $eImmunology 205 $a2nd ed. 210 $aBurlington $cElsevier Science$d2006 215 $a1 online resource (395 p.) 225 1 $aAmerican College of Laboratory Animal Medicine 300 $aDescription based upon print version of record. 311 $a0-12-369458-2 327 $aFront Cover; The Mouse in Biomedical Research: Immunology; Copyright Page; Table of Contents; List of Reviewers; List of Contributors; Foreword; Preface; Overview; Chapter 1. The Molecular Basis of Lymphoid Architecture in the Mouse; Chapter 2. The Biology of Toll-Like Receptors in Mice; Chapter 3. Genomic Organization of the Mouse Major Histocompatibility Complex; Chapter 4. Some Biological Features of Dendritic Cells in the Mouse; Chapter 5. Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes 327 $aChapter 6. Mouse Natural Killer Cells: Function and ActivationChapter 7. Cytokine-Activated JAK-STAT Signaling in the Mouse Immune System; Chapter 8. Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse; Chapter 9. Mouse Models of Negative Selection; Chapter 10. Peripheral Tolerance of T Cells in the Mouse; Chapter 11. The Genetics of Mouse Models of Systemic Lupus; Chapter 12. Inhibitory Receptors and Autoimmunity in the Mouse; Chapter 13. Mouse Models of Immunodeficiency; Chapter 14. Mouse Models to Study the Pathogenesis of Allergic Asthma 327 $aChapter 15. The Mouse Trap: How Well Do Mice Model Human Immunology?Index; Colour Plates 330 $aImmunology, the third volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, foll 410 0$aAmerican College of Laboratory Animal Medicine 606 $aMice as laboratory animals 606 $aMice as laboratory animals 606 $aMicrobiology & Immunology$2HILCC 606 $aAnimal Sciences$2HILCC 606 $aAgriculture$2HILCC 606 $aBiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 606 $aEarth & Environmental Sciences$2HILCC 608 $aElectronic books. 615 4$aMice as laboratory animals. 615 4$aMice as laboratory animals. 615 7$aMicrobiology & Immunology 615 7$aAnimal Sciences 615 7$aAgriculture 615 7$aBiology 615 7$aHealth & Biological Sciences 615 7$aEarth & Environmental Sciences 676 $a616.027333 676 $a616/.027333 700 $aFox$b James G$0874233 701 $aBarthold$b Stephen$0973148 701 $aDavisson$b Muriel$0973149 701 $aNewcomer$b Christian E$0973150 701 $aQuimby$b Fred W$0973151 701 $aSmith$b Abigail$0973152 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910458629703321 996 $aThe Mouse in Biomedical Research$92214086 997 $aUNINA