LEADER 03616nam 2200649Ia 450 001 9910458628003321 005 20200520144314.0 010 $a1-280-75151-7 010 $a9786610751518 010 $a0-08-046906-X 035 $a(CKB)1000000000364154 035 $a(EBL)285781 035 $a(OCoLC)476037267 035 $a(SSID)ssj0000206025 035 $a(PQKBManifestationID)11184718 035 $a(PQKBTitleCode)TC0000206025 035 $a(PQKBWorkID)10212583 035 $a(PQKB)11224393 035 $a(MiAaPQ)EBC285781 035 $a(Au-PeEL)EBL285781 035 $a(CaPaEBR)ebr10160337 035 $a(CaONFJC)MIL75151 035 $a(EXLCZ)991000000000364154 100 $a20060623d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHistory, wild mice, and genetics$b[electronic resource] /$fedited by James G. Fox ... [et al.] 205 $a2nd ed. 210 $aAmsterdam ;$aBoston, MA $cAcademic Press $cElsevier$dc2007 215 $a1 online resource (352 p.) 225 1 $aAmerican College of Laboratory Animal Medicine series 225 0 $aThe mouse in biomedical research ;$v1 300 $aDescription based upon print version of record. 311 $a0-12-369455-8 320 $aIncludes bibliographies and indexes. 327 $aFront Cover; The Mouse in Biomedical Research: History, Wild Mice, and Genetics; Copyright Page; Table of Contents; List of Reviewers; List of Contributors; Foreword; Preface; Chapter 1. Building a Better Mouse: One Hundred Years of Genetics and Biology; Chapter 2. Systematics of the genus Mus; Chapter 3. The Secret World of Wild Mice; Chapter 4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types; Chapter 5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide; Chapter 6. The Mouse Genome; Chapter 7. Gene Mapping; Chapter 8. Genetic Monitoring 327 $aChapter 9. CytogeneticsChapter 10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man; Chapter 11. Gamete and Embryo Manipulation; Chapter 12. Chemical Mutagenesis in Mice; Chapter 13. Gene-Specific Mutagenesis; Chapter 14. Gene Transfer Studies Using Mouse Models; Chapter 15. Mouse and Human Pluripotent Stem Cells; Chapter 16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics; Index; Colour Plates 330 $aHistory, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is descr 410 0$aAmerican College of Laboratory Animal Medicine series. 606 $aMice as laboratory animals 606 $aAnimal models in research 608 $aElectronic books. 615 0$aMice as laboratory animals. 615 0$aAnimal models in research. 676 $a616.027333 676 $a616.027334 701 $aFox$b James G$0874233 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910458628003321 996 $aHistory, wild mice, and genetics$91951940 997 $aUNINA