LEADER 05620nam 2200685 a 450 001 9910458620303321 005 20200520144314.0 010 $a1-281-02327-2 010 $a9786611023270 010 $a0-08-052529-6 035 $a(CKB)1000000000364084 035 $a(EBL)300912 035 $a(OCoLC)476079912 035 $a(SSID)ssj0000252394 035 $a(PQKBManifestationID)11191557 035 $a(PQKBTitleCode)TC0000252394 035 $a(PQKBWorkID)10176173 035 $a(PQKB)10357422 035 $a(MiAaPQ)EBC300912 035 $a(Au-PeEL)EBL300912 035 $a(CaPaEBR)ebr10179838 035 $a(CaONFJC)MIL102327 035 $a(EXLCZ)991000000000364084 100 $a20060714d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aStress and addiction$b[electronic resource] $ebiological and psychological mechanisms /$fedited by Mustafa al'Absi 210 $aAmsterdam ;$aBoston $cAcademic Press$dc2007 215 $a1 online resource (453 p.) 300 $aDescription based upon print version of record. 311 $a0-12-370632-7 320 $aIncludes bibliographical references and indexes. 327 $aFront Cover; Stress and Addiction: Biological and Psychological Mechanisms; Copyright Page; Contents; Contributors; Foreword; Preface; Acknowledgments; SECTION I: NEUROBIOLOGY OF STRESS AND ADDICTION; Chapter 1. Biological Bases of the Stress Response; I. Introduction; II. Physiological Stress Research; III. Major Components of the Biological Stress Response System; IV. Other Stress-Responsive Hormone Axes; V. Other Stress-Responsive Systems; VI. Final Remarks; References; Chapter 2. The Hypothalamic-Pituitary-Adrenal Axis and Addiction; I. Introduction; II. Stress and the HPA Axis 327 $aIII. Stress, the HPA Axis, and the Acquisition of Drug TakingIV. Stress and Vulnerability to Addiction in Humans; V. The HPA Axis and the Maintenance of Drug Taking; VI. Relapse to Addiction; VII. Inconsistencies; VIII. Conclusions and Implications for the Treatment of Addiction; References; Chapter 3. Dopaminergic Reward Pathways and Effects of Stress; I. Defining Stress; II. The Mesencephalic Dopamine System; III. Dopamine and Addiction; IV. Dopamine and Stress; V. Conclusions; References; Chapter 4. Endogenous Opiates, Addiction, and the Stress Response; I. Introduction 327 $aII. The Endogenous Opioid SystemIII. The Endogenous Opioid System and Reward and Reinforcement; IV. Effect of Alcohol on Endogenous Opioid Activity; V. Effect of Alcohol on Endogenous Opioid Receptors; VI. Endogenous Opioid Activity and Receptors and Alcohol Preference; VII. Opioid Antagonists in the Treatment of Alcohol Addiction; VIII. Endogenous Opioid Activity and Receptors and Cocaine Preference; IX. Opioid Antagonists in the Treatment of Cocaine Addiction; X. Opioids and Risk for Alcoholism; XI. The ?-Opioid Receptor Gene; XII. Conclusions; References 327 $aChapter 5. Early Life Stress and Vulnerability to AddictionI. Introduction; II. Neurohormonal Mechanisms of Stress Relevant to Cocaine Addiction; III. Animal Models; IV. Neurohormonal Effects of Neonatal Isolation; V. Behavioral Effects of Neonatal Isolation; VI. Sex Differences and Estrous Stage Effects of Neonatal Isolation; VII. Maternal Care Hypothesis; VIII. Conclusions and Translation for Clinical Relevance; References; Chapter 6. Genetics, Stress, and the Risk for Addiction; I. Introduction; II. The Extent of the Problem: Prevalence of Addiction; III. Heritability of Addiction 327 $aIV. HPA AxisV. The "Reward" Pathway of Addiction: Interaction with Stress; VI. Reward Pathway and Stress Response: Key Neurotransporter Systems; VII. Limbic Regulation of Response to Stress; VIII. The Locus Coeruleus (LC)-Norepinephrine (NE) System; IX. Conclusions; References; Chapter 7. Neurobiology of Stress and Risk for Relapse; I. Overview; II. Animal Models for Studying the Effects of Stress on Relapse to Drug Seeking: The Reinstatement Procedure; III. The Neurobiology of Stress-Induced Reinstatement of Drug Seeking 327 $aIV. Long-Lasting Changes in the Responsivity of the Central Nervous System to CRF: Behavioral and Neuroanatomical Studies with Potential Implications for Reinstatement 330 $aStress is one of the most commonly reported precipitants of drug use and is considered the number one cause of relapse to drug abuse. For the past several decades, there have been a number of significant advances in research focusing on the neurobiological and psychosocial aspects of stress and addiction; along with this growth came the recognition of the importance of understanding the interaction of biological and psychosocial factors that influence risk for initiation and maintenance of addictive behaviors. Recent research has started to specifically focus on understanding the nature of how 606 $aDrug abuse$xPhysiological aspects 606 $aStress (Psychology)$xPhysiological aspects 606 $aDrug abuse$xPsychological aspects 606 $aStress (Psychology) 608 $aElectronic books. 615 0$aDrug abuse$xPhysiological aspects. 615 0$aStress (Psychology)$xPhysiological aspects. 615 0$aDrug abuse$xPsychological aspects. 615 0$aStress (Psychology) 676 $a616.86 701 $aAbsi$b Mustafa al$0962090 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910458620303321 996 $aStress and addiction$92181329 997 $aUNINA