LEADER 05322nam 2200661Ia 450 001 9910458428503321 005 20200520144314.0 010 $a1-281-79558-5 010 $a9786611795580 010 $a0-08-054214-X 035 $a(CKB)1000000000384946 035 $a(EBL)369469 035 $a(OCoLC)476204787 035 $a(SSID)ssj0000254073 035 $a(PQKBManifestationID)12087430 035 $a(PQKBTitleCode)TC0000254073 035 $a(PQKBWorkID)10207047 035 $a(PQKB)11347342 035 $a(MiAaPQ)EBC369469 035 $a(PPN)132105063 035 $a(Au-PeEL)EBL369469 035 $a(CaPaEBR)ebr10251257 035 $a(CaONFJC)MIL179558 035 $a(EXLCZ)991000000000384946 100 $a20000609d2001 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSurgical research$b[electronic resource] /$fedited by Wiley W. Souba, Douglas W. Wilmore 210 $aSan Diego, CA $cAcademic Press$d2001 215 $a1 online resource (1489 p.) 300 $aDescription based upon print version of record. 311 $a0-12-655330-0 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Surgical Research; Copyright Page; Contents; Contributors; Foreword; Preface; Chapter 1. Getting Started; Text; Chapter 2. Assessing Available Information; I. Introduction; II. Sources of Information; III. Assessing Published Studies: External Measures of Quality; IV. How to Read and Evaluate Published Studies; V. Suggestions for the Future; References; Chapter 3. Organizing and Preliminary Planning for Surgical Research; I. Research as the Foundation of an Academic Surgical Career; II. Research Training; III. Choosing a Research Mentor; IV. Choosing a Research Topic 327 $aV. General Preparation VI. Experimental Preparation; VII. Grant Preparation; References; Chapter 4. Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents; I. Introduction; II. Research Utilizing Laboratory Animals; III. Human Subject Research; IV. Institutional Safety Committees; V. Summary; References; Chapter 5. Grantsmanship; I. Introduction; II. Common Myths, Misconceptions, and Mistruths; III. Grant Preparation-General Comments; IV. Grant Preparation-Specific Comments; V. Other Considerations; VI. Conclusions; References 327 $aChapter 6. Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations I. History of Informed Consent; II. United States Regulations Governing Informed Consent; III. Conclusion; References; Chapter 7. Animal Care and Maintenance; I. Introduction; II. Ethical and Regulatory Overview; III. Available Resources; IV. Surgical Facility Design; V. Anesthesia; VI. Anesthetic Recommendations by Species; VII. Analgesia; VIII. Resources; References; Chapter 8. Funding Strategies and Agencies: Academic-Industrial Relationships 327 $aIntellectual Property I. Introduction; II. Academic Agencies; III. Industry; IV. State Incubators and Local University Incubators; V. Intellectual Property; Chapter 9. Statistical Considerations; I. Introduction; II. Hypothesis Testing; III. Sample Size Calculations; IV. Summary; References; Chapter 10. Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment; I. Introduction; II. Dimensions of Risk; III. Data Sources; IV. Multivariate Modeling Framework; V. Incorporating Risk in Multivariate Models 327 $aVI. Approaches for Improved Estimates of Treatment Effectiveness in Nonexperimental Studies: The Propensity Score and Instrumental VariablesVII. Conclusions; References; Chapter 11. Measuring Surgical Outcomes; I. Introduction; II. Generic Measures of Health Status; III. Specific Measures of Health Status; IV. Utilities; V. Patient Satisfaction; References; Appendix: The SF-36V2 Health Survey Questionnaire; Chapter 12. Design of Clinical Trials; I. Introduction; II. Hypotheses, Specific Aims, and Endpoints; III. Patient Eligibility; IV. Structure of Clinical Trials; V. Treatment Plan 327 $aVI. Data Collection and Quality Assurance 330 $aWith the recent changes in the health care industry, surgeons face increasing pressure to devote their time to their clinical activities, thus limiting their research efforts. It is essential that young and creative individuals are encouraged to perform research and are given incentives to participate in research under the mentorship of more experienced research investigators.Surgical Research is the first book to include all the information necessary for the surgical scientist to perform a research experiment. 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