LEADER 03354nam 22006134a 450 001 9910458163303321 005 20200520144314.0 010 $a1-280-75813-9 010 $a0-19-151381-4 010 $a1-4294-2155-X 035 $a(CKB)1000000000400801 035 $a(EBL)422479 035 $a(OCoLC)437108718 035 $a(SSID)ssj0000182978 035 $a(PQKBManifestationID)11166913 035 $a(PQKBTitleCode)TC0000182978 035 $a(PQKBWorkID)10173472 035 $a(PQKB)10905270 035 $a(MiAaPQ)EBC422479 035 $a(Au-PeEL)EBL422479 035 $a(CaPaEBR)ebr10233692 035 $a(CaONFJC)MIL75813 035 $a(EXLCZ)991000000000400801 100 $a20041227d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIntroduction to the cellular and molecular biology of cancer$b[electronic resource] /$fMargaret A. Knowles, Peter J. Selby 205 $a4th ed. 210 $aNew York $cOxford University Press$d2005 215 $a1 online resource (555 p.) 300 $a"Oxford bioscience"--Cover. 311 $a0-19-852563-X 311 $a0-19-856853-3 327 $aContents; Contributors; 1 What is cancer?; 2 The causes of cancer; 3 Inherited susceptibility to cancer; 4 DNA repair and cancer; 5 Epigenetic events in cancer; 6 Molecular cytogenetics of cancer; 7 Oncogenes; 8 Tumour suppressor genes; 9 The cancer cell cycle; 10 Cellular immortalization and telomerase activation in cancer; 11 Growth factors and their signalling pathways in cancer; 12 Apoptosis: molecular physiology and significance for cancer therapeutics; 13 Mechanisms of viral carcinogenesis; 14 Cytokines and cancer; 15 Hormones and cancer; 16 The spread of tumours; 17 Tumour angiogenesis 327 $a18 Stem cells, haemopoiesis, and leukaemia19 Animal models of cancer; 20 The immunology of cancer; 21 The molecular pathology of cancer; 22 From transcriptome to proteome; 23 Local treatment of cancer; 24 Chemotherapy; 25 Radiotherapy and molecular radiotherapy; 26 Monoclonal antibodies and therapy; 27 Immunotherapy of cancer; 28 Cancer gene therapy; 29 Screening; 30 Conclusions and prospects; Index 330 $a. What is cancer?, L.M. Franks and Margaret A. Knowles. 2. The causes of cancer, Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3. Inherited Susceptibility to Cancer, D. Timothy Bishop. 4. DNA Repair and Cancer, Beate Koberle, John P. Wittschieben, and Richard D. Wood. 5. Epigenetic Events in Cancer, Jonathan C. Cheng and Peter A. Jones. 6. Molecular Cytogenetics of Cancer, Denise. Sheer and Janet Shipley. 7. Oncogenes, Margaret A. Knowles. 8. Tumour suppressor genes, Sonia Lain and David P. Lane. 9. The cancer cell cycle, Chris J. Norbury. 606 $aCancer$xMolecular aspects 606 $aCancer cells 608 $aElectronic books. 615 0$aCancer$xMolecular aspects. 615 0$aCancer cells. 676 $a616.99/4071 700 $aKnowles$b Margaret A$0982283 701 $aSelby$b P$g(Peter)$0982284 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910458163303321 996 $aIntroduction to the cellular and molecular biology of cancer$92242035 997 $aUNINA