LEADER 05251nam 22006494a 450 001 9910458075103321 005 20210920114904.0 010 $a1-280-96696-3 010 $a9786610966967 010 $a0-08-047249-4 035 $a(CKB)1000000000363644 035 $a(EBL)288770 035 $a(OCoLC)298344317 035 $a(SSID)ssj0000137996 035 $a(PQKBManifestationID)11137518 035 $a(PQKBTitleCode)TC0000137996 035 $a(PQKBWorkID)10096548 035 $a(PQKB)10606027 035 $a(MiAaPQ)EBC288770 035 $a(Au-PeEL)EBL288770 035 $a(CaPaEBR)ebr10169732 035 $a(CaONFJC)MIL96696 035 $a(EXLCZ)991000000000363644 100 $a20060314d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDevelopment of the nervous system$b[electronic resource] /$fDan H. Sanes, Thomas A. Reh, William A. Harris 205 $a2nd ed. 210 $aAmsterdam ;$aBoston $cElsevier$d2006 215 $a1 online resource (388 p.) 300 $aDescription based upon print version of record. 311 $a0-12-618621-9 320 $aIncludes bibliographical references (p. 323-360). 327 $aCover; Contents; Preface to the First Edition; Preface to the Second Edition; Chapter 1: Neural Induction; Development and Evolution of Neurons; Early Embryology of Metazoans; Derivation of Neural Tissue; Interactions with Neighboring Tissues in Making Neural Tissue; The Molecular Nature of the Neural Inducer; Conservation of Neural Induction; Interactions Among the Ectodermal Cells in Controlling Neuroblast Segregation; Notch, Delta, and Achaete Scute Genes in Vertebrates; Linking Induction to Proneural Activity; Summary; Chapter 2: Polarity and Segmentation 327 $aRegional Identity of the Nervous SystemThe Anterior-Posterior Axis and HOX Genes; HOX Gene Function in the Nervous System; Signaling Molecules that Pattern the Anterior-Posterior Axis in Vertebrates: Heads or Tails; Organizing Centers in the Developing Brain; Forebrain Development, Prosomeres, and PAX Genes; Dorsal-Ventral Polarity in the Neural Tube; Dorsal Neural Tube and Neural Crest; Patterning the Cerebral Cortex; Summary; Chapter 3: Genesis and Migration; Cell-Cycle Genes Control the Number of Neurons Generated during Development 327 $aCell Interactions Control the Number of Cells Made by ProgenitorsThe Generation of Neurons and GLIA; Cerebral Cortex Histogenesis; The Subventricular Zone: A Secondary Zone of Neurogenesis; Cerebellar Cortex Histogenesis; Molecular Mechanisms of Neuronal Migration; Postembryonic and Adult Neurogenesis; Summary; Chapter 4: Determination and Differentiation; Transcriptional Hierarchies in Invariant Lineages; Spatial and Temporal Coordinates of Determination; Asymmetric Cell Divisions and Asymmetric Fate; Generating Complexity through Cellular Interactions 327 $aSpecification and Differentiation through Cellular Interactions and Interactions with the Local EnvironmentCompetence and Histogenesis; The Interplay of Intrinsic and Extrinsic Influences in Histogenesis; Interpreting Gradients and the Spatial Organization of Cell Types; Summary; Chapter 5: Axon Growth and Guidance; The Growth Cone; The Dynamic Cytoskeleton; What Do Growth Cones Grow On?; What Provides Directional Information to Growth Cones?; Cell Adhesion and Labeled Pathways; Repulsive Guidance; Chemotaxis, Gradients, and Local Information; The Optic Pathway; The Midline 327 $aAttraction and Repulsion: Desensitization and AdaptationSignal Transduction; Summary; Chapter 6: Target Selection; Defasiculation; Target Recognition and Entry; Slowing Down and Branching; Border Patrol and Prevention of Inappropriate Targeting; Topographic Mapping; Chemospecificity and Ephrins; Shifting and Fine Tuning of Connections; The Third Dimension, Lamina-Specific Termination; Cellular and Synaptic Targeting; Sniffing Out Targets; Summary; Chapter 7: Naturally Occurring Neuron Death; What does Neuron Death Look Like?; Early Elimination of Progenitor Cells 327 $aHow Many Differentiated Neurons Die? 330 $aDevelopment of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal 606 $aDevelopmental neurophysiology 608 $aElectronic books. 615 0$aDevelopmental neurophysiology. 676 $a612.8 700 $aSanes$b Dan Harvey$0749559 701 $aReh$b Thomas A$0749560 701 $aHarris$b William A$0749561 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910458075103321 996 $aDevelopment of the nervous system$92476513 997 $aUNINA