LEADER 06049nam 22007572 450 001 9910457789403321 005 20151005020621.0 010 $a1-107-22024-6 010 $a1-107-08665-5 010 $a1-283-29614-4 010 $a9786613296146 010 $a1-139-12316-5 010 $a0-511-73617-7 010 $a1-139-11741-6 010 $a1-139-12807-8 010 $a1-139-11305-4 010 $a1-139-11524-3 035 $a(CKB)2550000000056560 035 $a(EBL)775115 035 $a(OCoLC)769341822 035 $a(SSID)ssj0000541735 035 $a(PQKBManifestationID)11368704 035 $a(PQKBTitleCode)TC0000541735 035 $a(PQKBWorkID)10514638 035 $a(PQKB)10920919 035 $a(UkCbUP)CR9780511736179 035 $a(MiAaPQ)EBC775115 035 $a(Au-PeEL)EBL775115 035 $a(CaPaEBR)ebr10502672 035 $a(CaONFJC)MIL329614 035 $a(EXLCZ)992550000000056560 100 $a20100329d2011|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSystems biology $esimulation of dynamic network states /$fBernhard Ø. Palsson$b[electronic resource] 210 1$aCambridge :$cCambridge University Press,$d2011. 215 $a1 online resource (xiii, 317 pages) $cdigital, PDF file(s) 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a1-107-00159-5 320 $aIncludes bibliographical references (p. 306-313) and index. 327 $aCover; Title; Copyright; Contents; Preface; 1 Introduction; 1.1 Biological networks; 1.2 Why build and study models?; 1.3 Characterizing dynamic states; 1.4 Formulating dynamic network models; 1.5 The basic information is in a matrix format; 1.6 Studying dynamic models; 1.7 Summary; 2 Basic concepts; 2.1 Properties of dynamic states; 2.2 Primer on rate laws; 2.3 More on aggregate variables; 2.4 Time-scale decomposition; 2.5 Network structure versus dynamics; 2.6 Physico-chemical effects; 2.7 Summary; Part I Simulation of dynamic states; 3 Dynamic simulation: the basic procedure 327 $a3.1 Numerical solutions3.2 Graphically displaying the solution; 3.3 Post-processing the solution; 3.4 Demonstration of the simulation procedure; 3.5 Summary; 4 Chemical reactions; 4.1 Basic properties of reactions; 4.2 The reversible linear reaction; 4.3 The reversible bilinear reaction; 4.4 Connected reversible linear reactions; 4.5 Connected reversible bilinear reactions; 4.6 Summary; 5 Enzyme kinetics; 5.1 Enzyme catalysis; 5.2 Deriving enzymatic rate laws; 5.3 Michaelis-Menten kinetics; 5.4 Hill kinetics for enzyme regulation; 5.5 The symmetry model; 5.6 Scaling dynamic descriptions 327 $a5.7 Summary6 Open systems; 6.1 Basic concepts; 6.2 Reversible reaction in an open environment; 6.3 Michaelis-Menten kinetics in an open environment; 6.4 Summary; Part II Biological characteristics; 7 Orders of magnitude; 7.1 Cellular composition and ultra-structure; 7.2 Metabolism; 7.2.1 What are typical concentrations?; 7.2.2 What are typical metabolic fluxes?; 7.2.3 What are typical turnover times?; 7.2.4 What are typical power densities?; 7.3 Macromolecules; 7.3.1 What are typical characteristics of a genome?; 7.3.2 What are typical protein concentrations?; 7.3.3 What are typical fluxes? 327 $a7.3.4 What are typical turnover times?7.4 Cell growth and phenotypic functions; 7.4.1 What are typical cell-specific production rates?; 7.4.2 Balancing the fluxes and composition in an entire cell; 7.5 Summary; 8 Stoichiometric structure; 8.1 Bilinear biochemical reactions; 8.2 Bilinearity leads to a tangle of cycles; 8.3 Trafficking of high-energy phosphate bonds; 8.3.1 The basic structure of the ``core'' module; 8.3.2 Buffering the energy charge; 8.3.3 Open system: long-term adjustment of the capacity; 8.4 Charging and recovering high-energy bonds; 8.5 Summary 327 $a9 Regulation as elementary phenomena9.1 Regulation of enzymes; 9.2 Regulatory signals: phenomenology; 9.3 The effects of regulation on dynamic states; 9.4 Local regulation with Hill kinetics; 9.4.1 Inhibition; 9.4.2 Activation; 9.5 Feedback inhibition of pathways; 9.6 Increasing network complexity; 9.6.1 Regulation of protein synthesis; 9.6.2 Tight regulation of enzyme activity; 9.7 Summary; Part III Metabolism; 10 Glycolysis; 10.1 Glycolysis as a system; 10.2 The stoichiometric matrix; 10.3 Defining the steady state; 10.4 Simulating mass balances: biochemistry 327 $a10.5 Pooling: towards systems biology 330 $aBiophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard Ø. Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dynamic models using metabolomic and fluxomic data. The Mass Action Stoichiometric Simulation (MASS) procedure can be used for any cellular process for which data is available and allows a scalable step-by-step approach to the practical construction of network models. Specifically, it can treat integrated processes that need explicit accounting of small molecules and protein, which allows simulation at the molecular level. The material has been class-tested by the author at both the undergraduate and graduate level. All computations in the text are available online in MATLAB and MATHEMATICA® workbooks, allowing hands-on practice with the material. 606 $aSystems biology 606 $aComputational biology 606 $aGenomics 606 $aBioinformatics 615 0$aSystems biology. 615 0$aComputational biology. 615 0$aGenomics. 615 0$aBioinformatics. 676 $a572.80285 700 $aPalsson$b Bernhard$0501629 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910457789403321 996 $aSystems biology$9726520 997 $aUNINA LEADER 03944nam 2200589Ia 450 001 996202850703316 005 20230421045217.0 010 $a1-282-31465-3 010 $a9786612314650 010 $a0-470-31481-8 010 $a0-470-31638-1 035 $a(CKB)1000000000687877 035 $a(EBL)702551 035 $a(OCoLC)769341613 035 $a(SSID)ssj0000715152 035 $a(PQKBManifestationID)11407937 035 $a(PQKBTitleCode)TC0000715152 035 $a(PQKBWorkID)10701289 035 $a(PQKB)10328662 035 $a(MiAaPQ)EBC702551 035 $a(EXLCZ)991000000000687877 100 $a19970429d1996 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 12$aA collection of papers presented at the 56th Conference on Glass Problems$b[electronic resource] $eOctober 24-25, 1995, Urbana, IL /$fsponsored by the Departments of Materials Science and Engineering at the University of Illinois at Urbana-Champaign and The Ohio State University; Gerald P. Wirtz, conference director 210 $aWesterville, OH $cAmerican Ceramic Society$dc1996 215 $a1 online resource (194 p.) 225 1 $aCeramic engineering & science proceedings ;$v17/2 300 $aDescription based upon print version of record. 311 $a0-470-37541-8 320 $aIncludes bibliographical references. 327 $aCeramic Engineering & Science Proceedings Volume 17, Issue 2, 1996; Table of Contents; A New Approach to Joint Research and Development: Determining the Potential for a Partnership Between the Glass Industry and the Federal Government; Title V Permits in the Glass Industry: Making Them Simple, Comprehensive, and Flexible; Glass Furnace NOx Control with Gas Reburn; Particulate Emissions in Oxy-Fuel Fired Glass Furnaces; Demonstration on an Ultra-Low-NOx Oxygen-Fuel Glass Melting System; Volatilization During Thermal Plasma Processing of Glass Melts Containing Heavy Metals 327 $aGlass Container Reuse: Refillables Hold Opportunity for Glass IndustryUse of Zinc Selenite in Glass Manufacture; Segregation Affects Glass Quality; Submerged Combustion Furnace for Glass Melts; Thermal Efficiencies of Float and Container Furnaces; Lift-Out Rolls and Lehr Rolls for Production of High-Quality Glass; Ongoing Investigation of Oxy-Fuel Firing Impact on Corrosion of Nonglass Contact Refractories, Part 2; Model-Based Evaluation of Oxy-Fuel Glass-Melting Furnace Performance; Design Modeling of Glass Furnace Oxy-Fuel Conversion Using Three-Dimensional Combustion Models 327 $aHeat Transfer Optimization in TV Glass FurnacesHigh-Performance Oxy-Fuel Melting: Three Flat Jet Burner Applications; Oxy-Fuel Economics Update Based on Case Histories; Is Your Glass Full of Water?; Corrosion of Silica and Mullite Refractories Used in Glass Furnaces Under 100% Oxy-Firing Process 330 $aThis volume is part of the Ceramic Engineering and Science Proceeding (CESP) series. This series contains a collection of papers dealing with issues in both traditional ceramics (i.e., glass, whitewares, refractories, and porcelain enamel) and advanced ceramics. Topics covered in the area of advanced ceramic include bioceramics, nanomaterials, composites, solid oxide fuel cells, mechanical properties and structural design, advanced ceramic coatings, ceramic armor, porous ceramics, and more. 410 0$aCeramic engineering and science proceedings ;$v17/2. 606 $aGlass$vCongresses 606 $aGlass manufacture$vCongresses 615 0$aGlass 615 0$aGlass manufacture 676 $a666.1 701 $aWirtz$b Gerald P$g(Gerald Paul),$f1937-$01344050 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996202850703316 996 $aA collection of papers presented at the 56th Conference on Glass Problems$93068628 997 $aUNISA LEADER 06458nam 22007695 450 001 9911001472903321 005 20240701121758.0 010 $a3-031-17918-8 024 7 $a10.1007/978-3-031-17918-1 035 $a(CKB)5580000000506602 035 $a(MiAaPQ)EBC7185850 035 $a(Au-PeEL)EBL7185850 035 $a(OCoLC)1369657366 035 $a(DE-He213)978-3-031-17918-1 035 $a(PPN)267809409 035 $a(EXLCZ)995580000000506602 100 $a20230124d2023 u| 0 101 0 $aeng 135 $aurcn#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCriminal Legalities and Minorities in the Global South $eRights and Resistance in a Decolonial World /$fedited by George B. Radics, Pablo Ciocchini 205 $a1st ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Palgrave Macmillan,$d2023. 215 $a1 online resource (303 pages) $cillustrations 225 1 $aPalgrave Socio-Legal Studies,$x2947-9282 311 08$a3-031-17917-X 320 $aIncludes bibliographical references and index. 327 $aPart I. Rebuilding after violence -- Chapter 1. The Caradiru Prison Massacre and Ongoing Military Repression in Brazil (Emilio Meyer, Marta Machado) -- Chapter 2. Politics before Law: The New Penal Code of 2017 and its Limited Protections for Ethnic Minorities in Post-Conflict Afghanistan (Bashir Mobasher, Nasiruddin Nezaami) -- Chapter 3. "Between denial and memory" a socio-legal reading of securitisation narratives in Transitional Colombia (Gustavo Rojas Paez). - Part II. Economic interest and the state -- Chapter 4. Enforcing Exclusion through the Law: The National Register of Citizens in India (Suraj Gogoi) -- Chapter 5. Colonial Legal Continuities in Post-Colonial Pakistan: A look at the construction of law, ownership and crime (Sabeen Kazmi) -- Chapter 6. (Cr)Immigration and Merit-Based Migration in the Global South: Policing "Alcoholic Indians" and "Bangladeshi Terrorists" in Singapore (George Radics) -- Chapter 7. Disciplining colonial subjects: Neoliberal Legalities, Disasters and the Criminalization of Protest in Puerto Rico (José Atiles Osoria) -- Part III. Entrenched cultural biases -- Chapter 8. "Truth" and "Consent" in Sexual Violence Reporting in Criminal Justice and Legal Contexts in Singapore (Dr Joseph Greener, Stacy Ooi). - Chapter 9. Between Toys and Behind Bars: Mothers in Jail in the State of Ceará, Brazil (Lara Nascimento Meneses, João Araújo Monteiro Neto, Nestor Eduardo Araruna Santiago) -- Chapter 10. The "War on Drugs" in Philippine Criminal Courts: Legal Professionals' Moral Discourse and Plea Bargaining in Drug-Related Cases (Pablo Ciocchini, Jayson Lamchek) -- Part IV. Criminalisation of Diversity. - Chapter 11. Circuits of Law: Everyday Criminalisation of Transgender Embodiment in Istanbul (Ezgi Ta?c?o?lu). - Chapter 12. Reaffirming Womanhood: Young transwomen and online sex work in Philippines (Veronica Gregorio) -- Chapter 13. A queer chinkhoswe: Reimagining the customary in Malawi (Nigel Timothy Mpemba Patel). 330 $a"Radics and Ciocchini have deftly curated the contributions of new and established scholars in a work that amply illustrates why scholarship from the Global South matters in building knowledge and shaping theory." -Dee Smythe, Professor and Director of the Centre for Law and Society at the University of Cape Town, South Africa "The editors and authors not only show us how violence manifests in the Global South but also what we can learn from the diverse ways in which these populations respond to oppressive conditions and engage with the law." -Lynette J. Chua, Associate Professor of Law at the National University of Singapore and President of the Asian Law & Society Association "Criminal Legalities' originality lies in the Southern perspective it adopts to document the specific forms that law and the criminal justice system take when they target disadvantaged groups in nations that are politically and culturally marginalized themselves." -Roberto Gargarella, Professor at the Universidad de Buenos Aires and Senior Researcher at National Research Center, Argentina This book explores how the law and the institutions of the criminal justice system expose minorities to different types of violence, either directly, through discrimination and harassment, or indirectly, by creating the conditions that make them vulnerable to violence from other groups of society. It draws on empirical insights across a broad array of communities and locales of the Global South. The book examines the challenges of protecting those at the margins of power, especially those whom the law is often used to oppress. George B. Radics is Senior Lecturer in the Department of Sociology and Anthropology at the National University of Singapore (NUS) and holds a joint appointment with NUS College. Pablo Ciocchini is Honorary Research Fellow in the Department of Sociology, Social Policyand Criminology at the University of Liverpool, UK, and Research Associate in the Institute for Legal Culture of the National University of La Plata, Argentina. 410 0$aPalgrave Socio-Legal Studies,$x2947-9282 606 $aLaw and the social sciences 606 $aHuman rights 606 $aCriminal law 606 $aCriminology 606 $aCritical criminology 606 $aSocial justice 606 $aSocio-Legal Studies 606 $aHuman Rights 606 $aCriminal Law and Criminal Procedure Law 606 $aCriminology in the Global South 606 $aCritical Criminology 606 $aSocial Justice 615 0$aLaw and the social sciences. 615 0$aHuman rights. 615 0$aCriminal law. 615 0$aCriminology. 615 0$aCritical criminology. 615 0$aSocial justice. 615 14$aSocio-Legal Studies. 615 24$aHuman Rights. 615 24$aCriminal Law and Criminal Procedure Law. 615 24$aCriminology in the Global South. 615 24$aCritical Criminology. 615 24$aSocial Justice. 676 $a364 676 $a345.124 702 $aRadics$b George B. 702 $aCiocchini$b Pablo Leandro$f1978- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911001472903321 996 $aCriminal Legalities and Minorities in the Global South$93058315 997 $aUNINA