LEADER 03456nam 2200637Ia 450 001 9910457437703321 005 20200520144314.0 010 $a1-280-70785-2 010 $a9786610707850 010 $a0-08-046550-1 035 $a(CKB)1000000000357890 035 $a(EBL)281987 035 $a(OCoLC)171113756 035 $a(SSID)ssj0000292454 035 $a(PQKBManifestationID)11213986 035 $a(PQKBTitleCode)TC0000292454 035 $a(PQKBWorkID)10269183 035 $a(PQKB)11602742 035 $a(MiAaPQ)EBC281987 035 $a(Au-PeEL)EBL281987 035 $a(CaPaEBR)ebr10151407 035 $a(CaONFJC)MIL70785 035 $a(OCoLC)935262545 035 $a(EXLCZ)991000000000357890 100 $a20061110d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCongenital and other related infectious diseases of the newborn$b[electronic resource] /$feditor: Isa K. Mushahwar 210 $aAmsterdam ;$aLondon $cElsevier$d2007 215 $a1 online resource (287 p.) 225 1 $aPerspectives in medical virology,$x0168-7069 ;$vv. 13 300 $aDescription based upon print version of record. 311 $a0-444-52073-2 320 $aIncludes bibliographical references and index. 327 $aCover; Congenital and Other Related Infectious Diseases of the Newborn; Copyright Page; Dedication; Contents; List of Contributors; Preface; Diagnosis of Maternal and Congenital Cytomegalovirus Infection; Herpes Simplex Virus Infections of the Newborn; Epidemiology of Herpes Viruses 6 and 7 in Children; Varicella-Zoster Virus Infections during Pregnancy; Human Immunodeficiency Viruses: Molecular Virology, Pathogenesis, Diagnosis and Treatment; Mother-to-Child Transmission of Human Immunodeficiency Virus Type 1; Hepatitis B Virus and Hepatitis C Virus: Molecular Biology and Diagnosis 327 $aPerinatal Hepatitis B Virus Infection in JapanHepatitis C in Pregnancy and Mother-to-Infant Transmission of HCV; Human Parvovirus B19: Molecular Virology, Clinical Features, Prevalence, Diagnosis and Control; Rubella Virus: Molecular Composition, Pathogenesis, Diagnosis, and Control; Congenital Chagas Disease; Color Section; Index 330 $aThis book is directed toward the molecular composition, pathogenesis, diagnosis, treatment and control of congenital and other related diseases of the newborn that are caused by a variety of viruses. These viruses comprise several families that include Herpesviridae (HSV-1, HSV-2, HSV-6, HSV-7, CMV and varcilla-zoster); Parvoviridae (parvovirus B19); Lentiviridae (HIV); Hepadnaviridae (HBV); Flaviviridae (HCV); and Togaviridae (RV). Leading researchers in childhood diseases and virology from Brazil, Germany, Ireland, Italy, Japan, Spain, and the United States of America report on the up-t 410 0$aPerspectives in medical virology ;$vv. 13. 606 $aCommunicable diseases in pregnancy 606 $aNeonatal infections 606 $aFetus$xDiseases 608 $aElectronic books. 615 0$aCommunicable diseases in pregnancy. 615 0$aNeonatal infections. 615 0$aFetus$xDiseases. 676 $a616.043 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910457437703321 996 $aCongenital and other related infectious diseases of the newborn$91919486 997 $aUNINA LEADER 03986nam 2200685Ia 450 001 9910144739703321 005 20170815151020.0 010 $a1-282-12387-4 010 $a9786612123870 010 $a0-470-98557-7 010 $a0-470-98556-9 035 $a(CKB)1000000000377303 035 $a(EBL)470483 035 $a(OCoLC)609849407 035 $a(SSID)ssj0000360016 035 $a(PQKBManifestationID)11244187 035 $a(PQKBTitleCode)TC0000360016 035 $a(PQKBWorkID)10317795 035 $a(PQKB)10624946 035 $a(MiAaPQ)EBC470483 035 $a(EXLCZ)991000000000377303 100 $a20070626d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aFatty acids and lipotoxicity in obesity and diabetes$b[electronic resource] /$feditors: Gregory Bock and Jamie Goode 210 $aLondon $cJohn Wiley$d2007 215 $a1 online resource (223 p.) 225 1 $aNovartis Foundation symposium ;$v286 300 $aDescription based upon print version of record. 311 $a0-470-05764-5 320 $aIncludes bibliographical references and index. 327 $aFATTY ACIDS AND LIPOTOXICITY IN OBESITY AND DIABETES; Contents; Chair's introduction; Transcriptional control of energy homeostasis through the PGC1 coactivators; DISCUSSION; Human obesity and insulin resistance: lessons from experiments of nature; DISCUSSION; Lipid-induced metabolic dysfunction in skeletal muscle; DISCUSSION; Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes; DISCUSSION; The role of lipin 1 in adipogenesis and lipid metabolism; DISCUSSION; The role of the AMP-activated protein kinase in the regulation of energy homeostasis; DISCUSSION 327 $aEndoplasmic reticulum stress and inflammation in obesity and type 2 diabetesDISCUSSION; The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis; DISCUSSION; Fatty acid transport in adipocytes and the development of insulin resistance; DISCUSSION; Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking; DISCUSSION; Lipid storage and mobilization pathways in yeast; DISCUSSION; Cide proteins and the development of obesity; DISCUSSION; General discussion I; Visualizing brown adipose tissue with FDG-PET 327 $aAdiponectin and adiponectin receptors in obesity-linked insulin resistanceDISCUSSION; Anti-inflammatory and antidiabetic roles of PPARy; DISCUSSION; Final Discussion; Nutrition, ageing and lipotoxicity; Contributor Index; Subject Index 330 $aThe potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic ß cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics in 410 0$aNovartis Foundation symposium ;$v286. 606 $aLipids$xMetabolism$vCongresses 606 $aFatty acids$vCongresses 606 $aAdipose tissues$vCongresses 606 $aObesity$vCongresses 606 $aDiabetes$vCongresses 608 $aElectronic books. 615 0$aLipids$xMetabolism 615 0$aFatty acids 615 0$aAdipose tissues 615 0$aObesity 615 0$aDiabetes 676 $a612.397 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144739703321 996 $aFatty acids and lipotoxicity in obesity and diabetes$92198556 997 $aUNINA