LEADER 05516nam 22007214a 450 001 9910457010703321 005 20200520144314.0 010 $a1-282-44109-4 010 $a9786612441097 010 $a981-279-741-6 035 $a(CKB)2550000000002523 035 $a(EBL)477233 035 $a(OCoLC)555905315 035 $a(SSID)ssj0000335702 035 $a(PQKBManifestationID)11268878 035 $a(PQKBTitleCode)TC0000335702 035 $a(PQKBWorkID)10277895 035 $a(PQKB)10063397 035 $a(MiAaPQ)EBC3050894 035 $a(WSP)00002042 035 $a(MiAaPQ)EBC477233 035 $a(Au-PeEL)EBL3050894 035 $a(CaPaEBR)ebr10361801 035 $a(CaONFJC)MIL244109 035 $a(Au-PeEL)EBL477233 035 $a(EXLCZ)992550000000002523 100 $a20090713d2009 uy 0 101 0 $aeng 135 $aurcuu|||uu||| 181 $ctxt 182 $cc 183 $acr 200 00$aChemistry and biology of ellagitannins$b[electronic resource] $ean underestimated class of bioactive plant polyphenols /$feditor, Ste?phane Quideau 210 $aHackensack, NJ $cWorld Scientific$dc2009 215 $a1 online resource (395 p.) 300 $aDescription based upon print version of record. 311 $a981-279-740-8 320 $aIncludes bibliographic references and index. 327 $aPreface; Contents; 1. Ellagitannins Renewed the Concept of Tannins; 1.1 Old and New Concepts of Tannins.; 1.1.1 About the chemical stability of ellagitannins.; 1.1.2 Definition of ellagitannins in the narrow and wider senses; 1.1.3 Stereochemistry of ellagitannins.; 1.1.4 Condensation of dehydroellagitannins with other substances; 1.1.5 Accumulation of an ellagitannin of specific structure in a plant.; 1.2 Distribution of Ellagitannins in the Plant Kingdom.; 1.3 Formation and Classification of Ellagitannins in Plants. 327 $a1.3.1 Oxidative biological transformations from gallotannins to ellagitannins and dehydroellagitannins1.3.2 Regiospecificity of the HHDP group on the glucose core, and its correlation to plant families; 1.3.3 C-glycosidic ellagitannins and complex tannins.; 1.3.3.1 Occurrence of C-glycosidic tannins in plants; 1.3.3.2 Biomimetic synthesis of C-glycosidic ellagitannins; 1.3.4 Oligomerization of ellagitannins leading to pentamers; 1.3.4.1 Oligomers as main components in a plant species; 1.3.4.2 Oligomerization via oxidative C-O and C-C coupling modes; 1.3.4.2.1 The GOG- and GOGOG-type units 327 $a1.3.4.2.2 The DOG and D(OG)2-type units 1.3.4.2.3 The GOD-type unit; 1.3.5 Macrocyclic oligomers; 1.3.6 Structural transformations of ellagitannin oligomers; 1.3.6.1 Isomerization of dimers via Smiles rearrangement; 1.3.6.2 Hydrolysis of ellagitannin oligomers into monomers.; 1.3.7 Seasonal transformations of ellagitannins in a plant; 1.3.8 Production of ellagitannins by tissue cultures; 1.4 Correlation of Ellagitannins of Various Oxidation Stages with Plant Evolution Systems.; 1.4.1 Classification of hydrolyzable tannins based on the oxidation stages of their polyphenolic functions 327 $a1.4.2 Correlation of the oxidation stages with Cronquist's system of plant evolution 1.4.3 Isolation of oxidized ellagitannin oligomers in specific plant orders; 1.5 Main Ellagitannin-Rich Medicinal Plants; 1.6 Properties and Primary Activities of Ellagitannins.; 1.6.1 Reduction, stabilization and precipitation of other substances by tannins, and solubilization of precipitates by excess tannin; 1.6.2 Indexes of tannin binding activity and reversal of tannin biological activities; 1.6.3 Antioxidant activities; 1.7. Biological and Pharmacological Activities 327 $a1.7.1 Antiviral, antimicrobial and immunomodulatory activities 1.7.2 Antitumor activities; 1.7.2.1 Inhibition of mutagenicity of carcinogens; 1.7.2.2 Inhibition of tumor promotion.; 1.7.2.3 Host-mediated antitumor activity.; 1.7.3 Induction of apoptosis.; 1.7.4 Effects on liver functions and others.; 1.7.5 Absorption and metabolism of ellagitannins in animals; 1.8 Bibliography; 2. Structural Diversity and Antimicrobial Activities of Ellagitannins; 2.1 Monomeric Ellagitannins; 2.1.1 Primary ellagitannins (HHDP esters); 2.1.2 Dehydroellagitannins; 2.1.3 Modified dehydroellagitannins 327 $a2.1.4 C-Glycosidic ellagitannins 330 $aThis book is the first of its kind that focuses on the chemistry and biology of ellagitannins, a special class of naturally occurring polyphenols which have so far not received the attention they deserve. These polyphenolic substances are found in many plants, including numerous food sources. They not only exhibit unique structural features that fascinate most chemists who are aware of their existence, but also express remarkable biological activities that have yet to attract the interest of the pharmaceutical industry. This is surprising because ellagitannins have been identified as active pr 606 $aPlant polyphenols 606 $aPlant bioactive compounds 606 $aPhytochemicals 606 $aTannins 608 $aElectronic books. 615 0$aPlant polyphenols. 615 0$aPlant bioactive compounds. 615 0$aPhytochemicals. 615 0$aTannins. 676 $a572.2 701 $aQuideau$b Ste?phane$0994172 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910457010703321 996 $aChemistry and biology of ellagitannins$92443760 997 $aUNINA