LEADER 01724oam 2200493zu 450 001 9910456343603321 005 20210721060144.0 010 $a1-4384-0129-9 035 $a(CKB)111000211284808 035 $a(SSID)ssj0000129290 035 $a(PQKBManifestationID)11139657 035 $a(PQKBTitleCode)TC0000129290 035 $a(PQKBWorkID)10078403 035 $a(PQKB)11574942 035 $a(MiAaPQ)EBC3406929 035 $a(EXLCZ)99111000211284808 100 $a20160829d1997 uy 101 0 $aeng 181 $ctxt 182 $cc 183 $acr 200 10$aConstructing knowledges : the politics of theory-building and pedagogy in composition 210 31$a[Place of publication not identified]$cState University of New York Press$d1997 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-7914-3343-9 606 $aEnglish language$xStudy and teaching$xRhetoric 606 $aEnglish language$xComposition and exercises$xStudy and teaching 606 $aReport writing$xStudy and teaching 606 $aEnglish$2HILCC 606 $aLanguages & Literatures$2HILCC 606 $aEnglish Language$2HILCC 615 0$aEnglish language$xStudy and teaching$xRhetoric 615 0$aEnglish language$xComposition and exercises$xStudy and teaching 615 0$aReport writing$xStudy and teaching 615 7$aEnglish 615 7$aLanguages & Literatures 615 7$aEnglish Language 676 $a808/.042/07 700 $aDobrin$b Sidney I$0976852 801 0$bPQKB 906 $aBOOK 912 $a9910456343603321 996 $aConstructing knowledges : the politics of theory-building and pedagogy in composition$92225369 997 $aUNINA LEADER 03405nam 22006255 450 001 9910254061003321 005 20230810213720.0 010 $a3-658-13234-5 024 7 $a10.1007/978-3-658-13234-7 035 $a(CKB)3710000000616478 035 $a(EBL)4454269 035 $a(SSID)ssj0001653989 035 $a(PQKBManifestationID)16433763 035 $a(PQKBTitleCode)TC0001653989 035 $a(PQKBWorkID)14982956 035 $a(PQKB)11256628 035 $a(DE-He213)978-3-658-13234-7 035 $a(MiAaPQ)EBC4454269 035 $a(PPN)192770985 035 $a(EXLCZ)993710000000616478 100 $a20160317d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAnalysis of Single-Cell Data $eODE Constrained Mixture Modeling and Approximate Bayesian Computation /$fby Carolin Loos 205 $a1st ed. 2016. 210 1$aWiesbaden :$cSpringer Fachmedien Wiesbaden :$cImprint: Springer Spektrum,$d2016. 215 $a1 online resource (108 p.) 225 1 $aBestMasters,$x2625-3615 300 $aDescription based upon print version of record. 311 $a3-658-13233-7 320 $aIncludes bibliographical references. 327 $aModeling and Parameter Estimation for Single-Cell Data -- ODE Constrained Mixture Modeling for Multivariate Data -- Approximate Bayesian Computation Using Multivariate Statistics. 330 $aCarolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information. Contents Modeling and Parameter Estimation for Single-Cell Data ODE Constrained Mixture Modeling for Multivariate Data Approximate Bayesian Computation Using Multivariate Statistics Target Groups Researchers and students in the fields of (bio-)mathematics, statistics, bioinformatics System biologists, biostatisticians, bioinformaticians The Author Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group ?Data-driven Computational Modeling?. 410 0$aBestMasters,$x2625-3615 606 $aBiomathematics 606 $aMathematics$xData processing 606 $aBioinformatics 606 $aMathematical and Computational Biology 606 $aComputational Mathematics and Numerical Analysis 606 $aComputational and Systems Biology 615 0$aBiomathematics. 615 0$aMathematics$xData processing. 615 0$aBioinformatics. 615 14$aMathematical and Computational Biology. 615 24$aComputational Mathematics and Numerical Analysis. 615 24$aComputational and Systems Biology. 676 $a510 700 $aLoos$b Carolin$4aut$4http://id.loc.gov/vocabulary/relators/aut$0755825 906 $aBOOK 912 $a9910254061003321 996 $aAnalysis of single-cell data$91523145 997 $aUNINA