LEADER 02364nam 2200637Ia 450 001 9910456128303321 005 20200520144314.0 010 $a1-280-18337-3 010 $a9786610183371 010 $a0-309-50067-2 035 $a(CKB)111069351128630 035 $a(EBL)3375396 035 $a(SSID)ssj0000136697 035 $a(PQKBManifestationID)11150287 035 $a(PQKBTitleCode)TC0000136697 035 $a(PQKBWorkID)10084012 035 $a(PQKB)11603556 035 $a(MiAaPQ)EBC3375396 035 $a(Au-PeEL)EBL3375396 035 $a(CaPaEBR)ebr10038669 035 $a(CaONFJC)MIL18337 035 $a(OCoLC)923256141 035 $a(EXLCZ)99111069351128630 100 $a20030619d2002 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDemographic assessment techniques in complex humanitarian emergencies$b[electronic resource] $esummary of a workshop /$fHolly Reed, rapporteur ; Roundtable on the Demography of Forced Migration, Committee on Population, National Research Council 210 $aWashington, DC $cNational Academy Press$dc2002 215 $a1 online resource (35 p.) 300 $aWorkshop held Sept. 20-21, 2000, under the auspices of the Committee on Population, National Research Council. 311 $a0-309-08497-0 320 $aIncludes bibliographical references (p. 16-17). 327 $a""Front Matter""; ""Preface""; ""Contents""; ""INTRODUCTION""; ""BACKGROUND""; ""ESTIMATING POPULATION SIZE AND STRUCTURE""; ""ESTIMATING MORTALITY RATES""; ""SUMMARY AND FINAL DISCUSSION""; ""NOTES""; ""REFERENCES""; ""Appendix Workshop Agenda and Participants September 20-21, 2000"" 606 $aHumanitarian assistance 606 $aRefugees 606 $aForced migration 606 $aWar relief 606 $aDemography$zDeveloping countries 608 $aElectronic books. 615 0$aHumanitarian assistance. 615 0$aRefugees. 615 0$aForced migration. 615 0$aWar relief. 615 0$aDemography 676 $a363.34 700 $aReed$b Holly$0884669 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910456128303321 996 $aDemographic assessment techniques in complex humanitarian emergencies$92450714 997 $aUNINA LEADER 04351nam 22007335 450 001 9910437607903321 005 20200705130000.0 010 $a1-283-52913-0 010 $a9786613841582 010 $a94-007-4590-7 024 7 $a10.1007/978-94-007-4590-2 035 $a(CKB)2670000000232781 035 $a(EBL)971832 035 $a(OCoLC)804664595 035 $a(SSID)ssj0000737089 035 $a(PQKBManifestationID)11433451 035 $a(PQKBTitleCode)TC0000737089 035 $a(PQKBWorkID)10773713 035 $a(PQKB)10921722 035 $a(DE-He213)978-94-007-4590-2 035 $a(MiAaPQ)EBC971832 035 $a(PPN)168338432 035 $a(EXLCZ)992670000000232781 100 $a20120726d2013 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDNA Repair of Cancer Stem Cells /$fedited by Lesley A Mathews, Stephanie M Cabarcas, Elain Hurt 205 $a1st ed. 2013. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2013. 215 $a1 online resource (179 p.) 300 $aDescription based upon print version of record. 311 $a94-007-9705-2 311 $a94-007-4589-3 320 $aIncludes bibliographical references and index. 327 $aPreface. -1 Introduction to Cancer stem cells.-2 DNA Repair Pathways and Mechanisms.-3 Resistance and DNA repair mechanisms of cancer stem cells: Potential molecular targets for therapy.-4 DNA Repair in Normal Stem Cells.-5 DNA Repair Mechanisms in Glioblastoma Cancer Stem Cells.-6 DNA Repair Mechanisms in Breast Cancer Stem Cells.7 DNA Repair Mechanisms in other Cancer Stem Cell models -- 8 Pancreatic cancer stem cells in tumor progression, metastasis, epithelial-mesenchymal transition and DNA repair.-9 Targeting Cancer Stem Cell Efficient DNA Repair Pathways: Screening for new therapeutics -- 10 The Future of DNA Repair and Cancer Stem Cells. Index. 330 $aThe existence of ?cancer stem cells? (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence.  CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types. . 606 $aMedicine 606 $aMolecular biology 606 $aCancer research 606 $aStem cells 606 $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 615 0$aMedicine. 615 0$aMolecular biology. 615 0$aCancer research. 615 0$aStem cells. 615 14$aBiomedicine, general. 615 24$aMolecular Medicine. 615 24$aCancer Research. 615 24$aStem Cells. 676 $a616.99 676 $a616.99/4071 702 $aMathews$b Lesley A$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCabarcas$b Stephanie M$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHurt$b Elain$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910437607903321 996 $aDNA Repair of Cancer Stem Cells$92531832 997 $aUNINA